Facile synthesis of monodisperse porous Cu2O nanospheres on reduced graphene oxide for non-enzymatic amperometric glucose sensing

Abstract In this work, well-defined monodisperse porous Cu 2 O nanospheres were facilely synthesized, using ionic liquid crystal 1-hexadecyl-2,3-dimethylimidazolium bromide ([C 16 MMIm]Br) as a soft template. The as-prepared Cu 2 O nanospheres were successfully anchored on the reduced graphene oxide nanosheets (RGOs) by simple ultrasonication. The RGOs-Cu 2 O nanocomposites showed high electrocatalytic activity toward glucose oxidation. Thus, a non-enzymatic amperometric glucose sensor was constructed with a wide linear range from 0.01 to 6 mM, low detection limit of 0.05 μM ( S/N  = 3), high selectivity (185 μA mM −1 ), and fast response (within 3 s). This strategy opens a new facile and simple chemical route to prepare porous metal oxides supported on RGOs with novel properties.

[1]  Kai Jiang,et al.  One-pot synthesis of graphene–cuprous oxide composite with enhanced photocatalytic activity , 2012 .

[2]  Xujie Yang,et al.  Graphene oxide doped polyaniline for supercapacitors , 2009 .

[3]  Xiaodong Wu,et al.  Graphene oxide--MnO2 nanocomposites for supercapacitors. , 2010, ACS nano.

[4]  S. Gwo,et al.  Facet-dependent and au nanocrystal-enhanced electrical and photocatalytic properties of Au-Cu2O core-shell heterostructures. , 2011, Journal of the American Chemical Society.

[5]  K. Sohn,et al.  SnO2/Graphene Composites with Self‐Assembled Alternating Oxide and Amine Layers for High Li‐Storage and Excellent Stability , 2013, Advanced materials.

[6]  Kai Jiang,et al.  Mesocrystalline Cu2O hollow nanocubes: synthesis and application in non-enzymatic amperometric detection of hydrogen peroxide and glucose , 2012 .

[7]  Zongping Shao,et al.  Fast lithium-ion insertion of TiO2 nanotube and graphene composites , 2013 .

[8]  Wei Chen,et al.  Graphene wrapped Cu2O nanocubes: non-enzymatic electrochemical sensors for the detection of glucose and hydrogen peroxide with enhanced stability. , 2013, Biosensors & bioelectronics.

[9]  Q. Hao,et al.  One-pot synthesis of graphene/SnO2/PEDOT ternary electrode material for supercapacitors , 2013 .

[10]  M. H. Chakrabarti,et al.  Progress in the electrochemical modification of graphene-based materials and their applications , 2013 .

[11]  G. Shen,et al.  Seed-mediated synthesis of copper nanoparticles on carbon nanotubes and their application in nonenzymatic glucose biosensors. , 2012, Analytica chimica acta.

[12]  Chang Ming Li,et al.  Direct growth of flower-like manganese oxide on reduced graphene oxide towards efficient oxygen reduction reaction. , 2013, Chemical communications.

[13]  Jin Zhai,et al.  Hierarchically ordered macro-mesoporous TiO₂-graphene composite films: improved mass transfer, reduced charge recombination, and their enhanced photocatalytic activities. , 2011, ACS nano.

[14]  A. Biswas,et al.  Graphene oxide-based hydrogels to make metal nanoparticle-containing reduced graphene oxide-based functional hybrid hydrogels. , 2012, ACS applied materials & interfaces.

[15]  Huaqiang Cao,et al.  ZnO@graphene composite with enhanced performance for the removal of dye from water , 2011 .

[16]  Jianping Gao,et al.  A facile method to synthesize supported Pd–Au nanoparticles using graphene oxide as the reductant and their extremely high electrocatalytic activity for the electrooxidation of methanol and ethanol , 2013 .

[17]  Mengqiu Jia,et al.  Preparation of graphene/Co3O4 composites by hydrothermal method and their electrochemical properties , 2013 .

[18]  Bei Wang,et al.  FACILE SYNTHESIS AND CHARACTERIZATION OF GRAPHENE NANOSHEETS , 2008 .

[19]  Rong Zhang,et al.  Highly sensitive glucose sensor based on pt nanoparticle/polyaniline hydrogel heterostructures. , 2013, ACS nano.

[20]  Yi Cui,et al.  Solution-processed graphene/MnO2 nanostructured textiles for high-performance electrochemical capacitors. , 2011, Nano letters.

[21]  Abdullah M. Asiri,et al.  A simple route for preparation of highly stable CuO nanoparticles for nonenzymatic glucose detection , 2012 .

[22]  Jianxin Zhang,et al.  Development of magnetic single-enzyme nanoparticles as electrochemical sensor for glucose determination , 2013 .

[23]  Yuping Wu,et al.  Fabrication of a graphene–cuprous oxide composite , 2009 .

[24]  Aicheng Chen,et al.  Nonenzymatic electrochemical glucose sensor based on nanoporous PtPb networks. , 2008, Analytical chemistry.

[25]  K. El-Khatib,et al.  Development of Cu2O/Carbon Vulcan XC-72 as non-enzymatic sensor for glucose determination. , 2011 .

[26]  Yuefei Zhang,et al.  Cuprous oxide nanoparticles dispersed on reduced graphene oxide as an efficient electrocatalyst for oxygen reduction reaction. , 2012, Chemical communications.

[27]  Chun Li,et al.  Flexible graphene films via the filtration of water-soluble noncovalent functionalized graphene sheets. , 2008, Journal of the American Chemical Society.

[28]  Xinhe Bao,et al.  Reduced graphene oxide as a catalyst for hydrogenation of nitrobenzene at room temperature. , 2011, Chemical communications.

[29]  G. Yin,et al.  Cu2O@reduced graphene oxide composite for removal of contaminants from water and supercapacitors , 2011 .

[30]  Yan Li,et al.  In situ growth of copper nanoparticles on multiwalled carbon nanotubes and their application as non-enzymatic glucose sensor materials , 2010 .

[31]  Wei Zhang,et al.  NiO/Graphene Composite for Enhanced Charge Separation and Collection in p-Type Dye Sensitized Solar Cell , 2011 .

[32]  Haiyan Wang,et al.  A novel solvothermal synthesis of Mn3O4/graphene composites for supercapacitors , 2013 .

[33]  Jun Liu,et al.  Glucose oxidase-graphene-chitosan modified electrode for direct electrochemistry and glucose sensing. , 2009, Biosensors & bioelectronics.

[34]  Min Liu,et al.  A novel glucose biosensor based on phosphonic acid-functionalized silica nanoparticles for sensitive detection of glucose in real samples , 2013 .

[35]  S. Stankovich,et al.  Synthesis of graphene-based nanosheets via chemical reduction of exfoliated graphite oxide , 2007 .

[36]  Jinwen Qin,et al.  Graphene-wrapped WO3 nanoparticles with improved performances in electrical conductivity and gas sensing properties , 2011 .

[37]  Jun Chen,et al.  A Leavening Strategy to Prepare Reduced Graphene Oxide Foams , 2012, Advanced materials.

[38]  Jianrong Chen,et al.  Solvothermal synthesis of Cu/Cu2O hollow microspheres for non-enzymatic amperometric glucose sensing , 2012 .

[39]  Hui Yang,et al.  Facile Synthesis, Shape Evolution, and Photocatalytic Activity of Truncated Cuprous Oxide Octahedron Microcrystals with Hollows , 2010 .

[40]  Jiali Zhang,et al.  Reduction of graphene oxide via L-ascorbic acid. , 2010, Chemical communications.

[41]  Feng Li,et al.  High-energy MnO2 nanowire/graphene and graphene asymmetric electrochemical capacitors. , 2010, ACS nano.

[42]  Tong Zhang,et al.  A novel non-enzymatic glucose sensor based on NiO hollow spheres , 2013 .