Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin.

[1]  M. Wolf,et al.  Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. , 2008, The New England journal of medicine.

[2]  T. Littlewood,et al.  Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration , 2008, Circulation research.

[3]  M. Emmett What does serum fibroblast growth factor 23 do in hemodialysis patients? , 2008, Kidney international.

[4]  M. de Vernejoul,et al.  Bone mass does not correlate with the serum fibroblast growth factor 23 in hemodialysis patients. , 2008, Kidney international.

[5]  L. Liaw,et al.  Osteopontin: A Multifunctional Molecule Regulating Chronic Inflammation and Vascular Disease , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[6]  Jason R. Stubbs,et al.  PHOSPHORUS METABOLISM AND MANAGEMENT IN CHRONIC KIDNEY DISEASE: Role of Fibroblast Growth Factor 23 in Phosphate Homeostasis and Pathogenesis of Disordered Mineral Metabolism in Chronic Kidney Disease , 2007, Seminars in dialysis.

[7]  P. Raggi,et al.  Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. , 2007, Kidney international.

[8]  C. Giachelli,et al.  Mechanisms of vascular calcification. , 2007, Advances in chronic kidney disease.

[9]  K. Hruska,et al.  Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy. , 2007, Journal of the American Society of Nephrology : JASN.

[10]  T. Strom,et al.  DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis , 2006, Nature Genetics.

[11]  Brian J. Bennett,et al.  Osteoprotegerin Inactivation Accelerates Advanced Atherosclerotic Lesion Progression and Calcification in Older ApoE−/− Mice , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[12]  P. Price,et al.  The Elastic Lamellae of Devitalized Arteries Calcify When Incubated in Serum: Evidence for a Serum Calcification Factor , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[13]  A. Ooshima,et al.  Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism. , 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[14]  M. Somerman,et al.  Regulation of Cementoblast Gene Expression by Inorganic Phosphate In Vitro , 2006, Calcified Tissue International.

[15]  M. Pfeffer,et al.  Relation Between Serum Phosphate Level and Cardiovascular Event Rate in People With Coronary Disease , 2005, Circulation.

[16]  P. Raggi,et al.  Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. , 2005, Kidney international.

[17]  G. Beck,et al.  Relationship of phosphorus and calcium-phosphorus product with mortality in CKD. , 2005, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[18]  M. McKee,et al.  Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro. , 2005, Cardiovascular research.

[19]  C. Giachelli,et al.  Mitigation of Ectopic Calcification in Osteopontin-Deficient Mice by Exogenous Osteopontin , 2005, Calcified Tissue International.

[20]  P. Orlik,et al.  An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. , 2005, Human molecular genetics.

[21]  B. Kestenbaum,et al.  Serum phosphate levels and mortality risk among people with chronic kidney disease. , 2005, Journal of the American Society of Nephrology : JASN.

[22]  Z. Massy,et al.  Uremia accelerates both atherosclerosis and arterial calcification in apolipoprotein E knockout mice. , 2004, Journal of the American Society of Nephrology : JASN.

[23]  M. Razzaque,et al.  Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. , 2004, Matrix biology : journal of the International Society for Matrix Biology.

[24]  C. Ohlsson,et al.  Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. , 2004, Endocrinology.

[25]  E. Ritz,et al.  Overview: increased cardiovascular risk in patients with minor renal dysfunction: an emerging issue with far-reaching consequences. , 2004, Journal of the American Society of Nephrology : JASN.

[26]  Y. Takeuchi,et al.  Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. , 2004, The Journal of clinical investigation.

[27]  B. Gallimore,et al.  Characterization of a mouse model of chronic uremia , 2004, Urological Research.

[28]  H. Liapis,et al.  Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia. , 2003, Kidney international.

[29]  G. London,et al.  Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. , 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[30]  K. Hruska,et al.  BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. , 2003, Journal of the American Society of Nephrology : JASN.

[31]  Sharon M Moe,et al.  Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells. , 2002, Kidney international.

[32]  R. Guldberg,et al.  Inactivation of the Osteopontin Gene Enhances Vascular Calcification of Matrix Gla Protein–deficient Mice , 2002, The Journal of experimental medicine.

[33]  M. Bahner,et al.  Advanced Coronary and Carotid Arteriopathy in Young Adults With Childhood-Onset Chronic Renal Failure , 2002, Circulation.

[34]  P. Raggi,et al.  Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. , 2002, Kidney international.

[35]  P. Raggi,et al.  Phosphorus restriction and control of coronary calcification as assessed by electron beam tomography , 2002, Current opinion in nephrology and hypertension.

[36]  K. Hruska,et al.  Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7. , 2002, Kidney international.

[37]  P. Raggi,et al.  Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease? , 2002, Journal of the American College of Cardiology.

[38]  Sharon M Moe,et al.  Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins. , 2002, Kidney international.

[39]  R. Aebersold,et al.  Smooth Muscle Cell Phenotypic Transition Associated With Calcification: Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers , 2001, Circulation research.

[40]  J. Blacher,et al.  Arterial Calcifications, Arterial Stiffness, and Cardiovascular Risk in End-Stage Renal Disease , 2001, Hypertension.

[41]  A. Lusis,et al.  New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. , 2001, Physiological genomics.

[42]  C. Stehman-Breen,et al.  Risk factors and mortality associated with calciphylaxis in end-stage renal disease. , 2001, Kidney international.

[43]  A. Evan,et al.  Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[44]  J. Skepper,et al.  Apoptosis Regulates Human Vascular Calcification In Vitro: Evidence for Initiation of Vascular Calcification by Apoptotic Bodies , 2000, Circulation research.

[45]  M. McKee,et al.  Phosphate regulation of vascular smooth muscle cell calcification. , 2000, Circulation research.

[46]  E. Moran,et al.  Phosphate is a specific signal for induction of osteopontin gene expression. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[47]  C. Giachelli,et al.  Phosphorylation of Osteopontin Is Required for Inhibition of Vascular Smooth Muscle Cell Calcification* , 2000, The Journal of Biological Chemistry.

[48]  R. Elashoff,et al.  Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. , 2000, The New England journal of medicine.

[49]  P. Weissberg,et al.  Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. , 1999, Circulation.

[50]  P. Eskildsen,et al.  Bone mineral density and biochemical markers of bone turnover in patients with predialysis chronic renal failure. , 1999, Kidney international.

[51]  M D McKee,et al.  Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. , 1999, Circulation research.

[52]  A. Disney,et al.  Cutaneous necrosis from calcific uremic arteriolopathy. , 1998, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[53]  R. Foley,et al.  Cardiovascular disease and mortality in ESRD. , 1998, Journal of nephrology.

[54]  F. Port,et al.  Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. , 1998, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[55]  W. Bloembergen Cardiac disease in chronic uremia: epidemiology. , 1997, Advances in renal replacement therapy.

[56]  M. Fishbein,et al.  Genetic determination of cartilaginous metaplasia in mouse aorta. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[57]  C. Alpers,et al.  Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. , 1993, The Journal of clinical investigation.

[58]  L. Ibels,et al.  Arterial calcification and pathology in uremic patients undergoing dialysis. , 1979, The American journal of medicine.