Recognition and management of complications during transcatheter aortic valve implantation

In the field of interventional cardiology, transcatheter aortic valve implantation is the newest and most exciting development of recent years. With a growing evidence base for both prognostic and symptomatic benefit, more and more interventionalists are keen to learn the procedure. However, the concomitant risk associated with a technically challenging procedure in a high-risk patient population is significant, and complications can arise suddenly and often unexpectedly. It is essential that new, and even established, operators are meticulously aware of the potential for complications, are able to identify them at an early stage, and manage them quickly and effectively. We have significant experience with transcatheter aortic valve implantation, through the implantation of 260 devices, which brings first-hand experience of most major complications. This article provides insight into the potential for complications, offering advice on effective treatment, recognition, and ultimately, prevention. It also suggests a number of procedural and technical modifications, which might improve outcomes in the future.

[1]  Lukas Altwegg,et al.  Mitral valve injury late after transcatheter aortic valve implantation. , 2009, The Journal of thoracic and cardiovascular surgery.

[2]  A. Cook,et al.  Permanent Pacemaker Insertion After CoreValve Transcatheter Aortic Valve Implantation: Incidence and Contributing Factors (the UK CoreValve Collaborative) , 2011, Circulation.

[3]  EberhardGrube,et al.  Progress and Current Status of Percutaneous Aortic Valve Replacement: Results of Three Device Generations of the CoreValve Revalving System , 2008 .

[4]  U. Gerckens,et al.  Percutaneous aortic valve replacement , 2006 .

[5]  Alain Prat,et al.  Transcatheter aortic valve implantation: early results of the FRANCE (FRench Aortic National CoreValve and Edwards) registry. , 2011, European heart journal.

[6]  E. Tay,et al.  An embolic deflection device for aortic valve interventions. , 2010, JACC. Cardiovascular interventions.

[7]  P. Théroux,et al.  Prognostic significance of newly acquired bundle branch block after aortic valve replacement. , 2004, The American journal of cardiology.

[8]  S. Pocock,et al.  Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. , 2010, The New England journal of medicine.

[9]  M. Forsting,et al.  Silent and Apparent Cerebral Ischemia After Percutaneous Transfemoral Aortic Valve Implantation: A Diffusion-Weighted Magnetic Resonance Imaging Study , 2010, Circulation.

[10]  P. Serruys,et al.  2-year follow-up of patients undergoing transcatheter aortic valve implantation using a self-expanding valve prosthesis. , 2011, Journal of the American College of Cardiology.

[11]  B. Gogas,et al.  Acute coronary occlusion following TAVI , 2011, Catheterization and cardiovascular interventions.

[12]  J. Fajadet,et al.  Thirty-day outcome and vascular complications after transarterial aortic valve implantation using both Edwards Sapien and Medtronic CoreValve bioprostheses in a mixed population. , 2010, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[13]  Lukas Altwegg,et al.  Prevention and management of transcatheter balloon‐expandable aortic valve malposition , 2008, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[14]  Philippe Pibarot,et al.  Usefulness of TEE as the primary imaging technique to guide transcatheter transapical aortic valve implantation. , 2011, JACC. Cardiovascular imaging.

[15]  M. Mack,et al.  United States feasibility study of transcatheter insertion of a stented aortic valve by the left ventricular apex. , 2008, The Annals of thoracic surgery.

[16]  M. Sherif,et al.  Successful percutaneous coronary intervention after implantation of a CoreValve percutaneous aortic valve , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[17]  Jeroen J. Bax,et al.  Noncoronary applications of cardiac multidetector row computed tomography. , 2008, JACC. Cardiovascular imaging.

[18]  Acute left main obstructions following TAVI. , 2010, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[19]  G. Latsios,et al.  Procedural and mid-term results in patients with aortic stenosis treated with implantation of 2 (in-series) CoreValve prostheses in 1 procedure. , 2010, JACC. Cardiovascular interventions.

[20]  J. Webb Coronary obstruction due to transcatheter valve implantation , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[21]  Thomas Walther,et al.  Thirty-Day Results of the SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) Registry: A European Registry of Transcatheter Aortic Valve Implantation Using the Edwards SAPIEN Valve , 2010, Circulation.

[22]  H. Eggebrecht,et al.  Transcatheter aortic valve implantation: first results from a multi-centre real-world registry. , 2011, European heart journal.

[23]  O. Alfieri,et al.  A new technique for vascular access management in transcatheter aortic valve implantation , 2010, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[24]  A. Cheung,et al.  Atrioventricular block after transcatheter balloon expandable aortic valve implantation. , 2008, JACC. Cardiovascular interventions.

[25]  R. Tölg,et al.  Anatomic and procedural predictors of paravalvular aortic regurgitation after implantation of the Medtronic CoreValve bioprosthesis. , 2010, Journal of the American College of Cardiology.

[26]  R. Erbel,et al.  Vascular Access Site Complications after Percutaneous Transfemoral Aortic Valve Implantation , 2009, Herz Kardiovaskuläre Erkrankungen.

[27]  SarahGeisbüsch,et al.  Incidence and Management of CoreValve Dislocation During Transcatheter Aortic Valve Implantation , 2010 .

[28]  Lukas Altwegg,et al.  Percutaneous Transarterial Aortic Valve Replacement in Selected High-Risk Patients With Aortic Stenosis , 2007, Circulation.

[29]  Thomas Felderhoff,et al.  Percutaneous Implantation of the CoreValve Self-Expanding Valve Prosthesis in High-Risk Patients With Aortic Valve Disease: The Siegburg First-in-Man Study , 2006 .

[30]  P. Serruys,et al.  Implantation of two self‐expanding aortic bioprosthetic valves during the same procedure—Insights into valve‐in‐valve implantation (“Russian doll concept”) , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[31]  G. Schuler,et al.  Aortic regurgitation after transcatheter aortic valve implantation: incidence and early outcome. Results from the German transcatheter aortic valve interventions registry , 2011, Heart.

[32]  Susheel Kodali,et al.  ranscatheter Aortic Valve Implantation eview of the Nature , Management , and Avoidance of Procedural Complications , 2022 .

[33]  M. Cotrufo,et al.  Risk factors for pacemaker implantation following aortic valve replacement: a single centre experience , 2003, Heart.

[34]  Mauro Rinaldi,et al.  Aortic valve replacement and mitral valve repair as treatment of complications after percutaneous core valve implantation. , 2009, The Journal of thoracic and cardiovascular surgery.

[35]  Anson Cheung,et al.  Transapical Transcatheter Aortic Valve Implantation in Humans: Initial Clinical Experience , 2006, Circulation.

[36]  R. Cury,et al.  Evaluation of aortic root and valve calcifications by multi-detector computed tomography. , 2009, The Journal of heart valve disease.

[37]  Fabian Nietlispach,et al.  Transcatheter Aortic Valve Implantation: Impact on Clinical and Valve-Related Outcomes , 2009, Circulation.

[38]  P. Serruys,et al.  Procedural and 30-day outcomes following transcatheter aortic valve implantation using the third generation (18 Fr) corevalve revalving system: results from the multicentre, expanded evaluation registry 1-year following CE mark approval. , 2008, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[39]  R. Erbel,et al.  Usefulness of a novel balloon-expandable vascular sheath for facilitated large-bore arterial access for transcatheter aortic valve implantation. , 2011, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[40]  M. Cheitlin Percutaneous Aortic Valve Implantation Retrograde From the Femoral Artery , 2007 .

[41]  P. Serruys,et al.  Vascular complications with transcatheter aortic valve implantation using the 18 Fr Medtronic CoreValve System: the Rotterdam experience. , 2010, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[42]  U. Gerckens,et al.  Iatrogenic dissection of the ascending aorta during TAVI sealed with the corevalve revalving prosthesis , 2011, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[43]  A. Cribier,et al.  Treatment of calcific aortic stenosis with the percutaneous heart valve: mid-term follow-up from the initial feasibility studies: the French experience. , 2006, Journal of the American College of Cardiology.

[44]  Alec Vahanian,et al.  Determinants of significant paravalvular regurgitation after transcatheter aortic valve: implantation impact of device and annulus discongruence. , 2009, JACC. Cardiovascular interventions.

[45]  F. Maisano,et al.  Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis , 2011, Circulation.

[46]  G. Nickenig,et al.  Renal function as predictor of mortality in patients after percutaneous transcatheter aortic valve implantation. , 2010, JACC: Cardiovascular Interventions.

[47]  Y. Castier,et al.  Vascular complications of transfemoral aortic valve implantation with the Edwards SAPIEN prosthesis: incidence and impact on outcome. , 2010, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[48]  Robert H. Anderson,et al.  Early and persistent intraventricular conduction abnormalities and requirements for pacemaking after percutaneous replacement of the aortic valve. , 2008, JACC. Cardiovascular interventions.

[49]  Thierry Carrel,et al.  Risk of acute kidney injury in patients with severe aortic valve stenosis undergoing transcatheter valve replacement. , 2009, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[50]  Pascal Vranckx,et al.  Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium. , 2011, Journal of the American College of Cardiology.

[51]  B. De Bruyne,et al.  Procedural, 30-day and one year outcome following CoreValve or Edwards transcatheter aortic valve implantation: results of the Belgian national registry. , 2011, Interactive cardiovascular and thoracic surgery.