Ubiquitin-Proteasome System: Promising Therapeutic Targets in Autoimmune and Neurodegenerative Diseases
暂无分享,去创建一个
A. Palotás | K. Venkataraman | A. Rizvanov | S. Khaiboullina | E. Bulatov | H. J. dos Reis | Mookambeswaran Vijayalakshmi
[1] Robert H. Brown,et al. CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia , 2016, Nature Communications.
[2] A. Ciulli,et al. Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases , 2015, PloS one.
[3] A. Ciulli,et al. Targeting Cullin–RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation , 2015, The Biochemical journal.
[4] T. Spector,et al. Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus , 2015, The Lancet.
[5] T. Spector,et al. UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases , 2015, American journal of human genetics.
[6] W. Lems,et al. Proteasome inhibitors as experimental therapeutics of autoimmune diseases , 2015, Arthritis Research & Therapy.
[7] N. Jha,et al. Tau phosphorylation, molecular chaperones, and ubiquitin E3 ligase: clinical relevance in Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.
[8] P. Grandi,et al. Biophysical Studies on Interactions and Assembly of Full-size E 3 Ubiquitin Ligase SUPPRESSOR OF CYTOKINE SIGNALING 2 ( SOCS 2 )-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 ( RBX 2 ) * , 2015 .
[9] V. Negi,et al. Immunoglobulin-like transcripts 6 (ILT6) polymorphism influences the anti-Ro60/52 autoantibody status in south Indian SLE patients , 2014, Lupus.
[10] Steven P. Gygi,et al. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization , 2013, Nature.
[11] K. Ozato,et al. Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus , 2012, International journal of rheumatology.
[12] Y. Shintani,et al. FBL2 Regulates Amyloid Precursor Protein (APP) Metabolism by Promoting Ubiquitination-Dependent APP Degradation and Inhibition of APP Endocytosis , 2012, The Journal of Neuroscience.
[13] G. Schett,et al. Refractory SLE patients respond to the proteasome inhibitor bortezomib , 2012 .
[14] T. Muchamuel,et al. Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody-secreting cells. , 2012, Arthritis and rheumatism.
[15] Y. Nomura,et al. Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: possible involvement of HRD1, a novel molecule related to endoplasmic reticulum stress, in Alzheimer's disease. , 2012, Journal of pharmacological sciences.
[16] G. van Loo,et al. Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease. , 2011, Biochemical Society transactions.
[17] P. Gregersen,et al. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus , 2011, Nature Genetics.
[18] H. Anders,et al. Mdm 2 Promotes Systemic Lupus Erythematosus and Lupus Nephritis , 2011 .
[19] Rudi Beyaert,et al. Expression, biological activities and mechanisms of action of A20 (TNFAIP3). , 2010, Biochemical pharmacology.
[20] C. Liu,et al. The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. , 2010, Immunity.
[21] N. Hattori,et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy , 2010, The Journal of cell biology.
[22] R. Youle,et al. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy , 2008, The Journal of cell biology.
[23] David Altshuler,et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus , 2008, Nature Genetics.
[24] Hiderou Yoshida,et al. ER stress and diseases , 2007, The FEBS journal.