Socioeconomic inequalities in cervical precancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia and Zimbabwe: analysis of Population-Based HIV Impact Assessment surveys

Objectives We examined age, residence, education and wealth inequalities and their combinations on cervical precancer screening probabilities for women. We hypothesised that inequalities in screening favoured women who were older, lived in urban areas, were more educated and wealthier. Design Cross-sectional study using Population-Based HIV Impact Assessment data. Setting Ethiopia, Malawi, Rwanda, Tanzania, Zambia and Zimbabwe. Differences in screening rates were analysed using multivariable logistic regressions, controlling for age, residence, education and wealth. Inequalities in screening probability were estimated using marginal effects models. Participants Women aged 25–49 years, reporting screening. Outcome measures Self-reported screening rates, and their inequalities in percentage points, with differences of 20%+ defined as high inequality, 5%–20% as medium, 0%–5% as low. Results The sample size of participants ranged from 5882 in Ethiopia to 9186 in Tanzania. The screening rates were low in the surveyed countries, ranging from 3.5% (95% CI 3.1% to 4.0%) in Rwanda to 17.1% (95% CI 15.8% to 18.5%) and 17.4% (95% CI 16.1% to 18.8%) in Zambia and Zimbabwe. Inequalities in screening rates were low based on covariates. Combining the inequalities led to significant inequalities in screening probabilities between women living in rural areas aged 25–34 years, with a primary education level, from the lowest wealth quintile, and women living in urban areas aged 35–49 years, with the highest education level, from the highest wealth quintile, ranging from 4.4% in Rwanda to 44.6% in Zimbabwe. Conclusions Cervical precancer screening rates were inequitable and low. No country surveyed achieved one-third of the WHO’s target of screening 70% of eligible women by 2030. Combining inequalities led to high inequalities, preventing women who were younger, lived in rural areas, were uneducated, and from the lowest wealth quintile from screening. Governments should include and monitor equity in their cervical precancer screening programmes.

[1]  Paul Kawale,et al.  Cervical cancer prevention in Africa: A policy analysis , 2022, Journal of cancer policy.

[2]  Eleazar. Ndabarora,et al.  Uptake of Cervical Cancer Screening and Associated Factors Among Women Attending Outpatient Services in Rwamagana Hospital, Rwanda , 2021, Rwanda Journal of Medicine and Health Sciences.

[3]  E. Idemudia,et al.  Determinants and levels of cervical Cancer screening uptake among women of reproductive age in South Africa: evidence from South Africa Demographic and health survey data, 2016 , 2021, BMC Public Health.

[4]  M. Bayati,et al.  Global socioeconomic inequality in the burden of communicable and non-communicable diseases and injuries: an analysis on global burden of disease study 2019 , 2021, BMC Public Health.

[5]  P. Bracke,et al.  Cervical cancer screening programs and their context-dependent effect on inequalities in screening uptake: a dynamic interplay between public health policy and welfare state redistribution , 2021, International Journal for Equity in Health.

[6]  S. Yaya,et al.  Factors associated with and socioeconomic inequalities in breast and cervical cancer screening among women aged 15–64 years in Botswana , 2021, PloS one.

[7]  M. Fitch,et al.  Knowledge, utilization and barriers of cervical cancer screening among women attending selected district hospitals in Kigali - Rwanda. , 2021, Canadian oncology nursing journal = Revue canadienne de nursing oncologique.

[8]  M. Egger,et al.  Cervical Cancer Screening Cascade for women living with HIV: A cohort study from Zimbabwe , 2021, PLOS global public health.

[9]  Miquel Duran-Frigola,et al.  Cervical cancer screening outcomes in Zambia, 2010-19: a cohort study. , 2021, The Lancet. Global health.

[10]  A. Binagwaho,et al.  Screen, Notify, See, and Treat: Initial Results of Cervical Cancer Screening and Treatment in Rwanda , 2021, JCO global oncology.

[11]  A. Obse,et al.  Explaining socioeconomic disparities and gaps in the use of antenatal care services in 36 countries in sub-Saharan Africa , 2021, Health policy and planning.

[12]  Y. Woo,et al.  Achieving equity in cervical cancer screening in low- and middle-income countries (LMICs): Strengthening health systems using a systems thinking approach. , 2021, Preventive medicine.

[13]  Zhifei He,et al.  Socioeconomic Determinants of Maternal HealthCare Utilisation in Zambia: 1997-2014 , 2021, Inquiry : a journal of medical care organization, provision and financing.

[14]  U. Kluge,et al.  Tanzanian women´s knowledge about Cervical Cancer and HPV and their prevalence of positive VIA cervical screening results. Data from a Prevention and Awareness Campaign in Northern Tanzania, 2017 – 2019 , 2020, Global health action.

[15]  F. Bray,et al.  Estimates of the global burden of cervical cancer associated with HIV , 2020, The Lancet. Global health.

[16]  A. Ayenew,et al.  Uptake of cervical cancer screening service and associated factors among age-eligible women in Ethiopia: systematic review and meta-analysis , 2020, Infectious Agents and Cancer.

[17]  Michael Ekholuenetale,et al.  Prevalence and determinants of cervical cancer awareness among women of reproductive age: evidence from Benin and Zimbabwe population-based data , 2020, Applied Cancer Research.

[18]  P. Bracke,et al.  Never and under cervical cancer screening in Switzerland and Belgium: trends and inequalities , 2020, BMC Public Health.

[19]  A. Longatto-Filho,et al.  Universal cervical cancer control through a right to health lens: refocusing national policy and programmes on underserved women , 2020, BMC International Health and Human Rights.

[20]  A. Pulkki-Brännström,et al.  Socioeconomic inequalities in women’s access to health care: has Ecuadorian health reform been successful? , 2020, International Journal for Equity in Health.

[21]  Paul Kawale,et al.  “It is big because it’s ruining the lives of many people in Malawi”: Women’s attitudes and beliefs about cervical cancer , 2020, Preventive medicine reports.

[22]  Khorshed Alam,et al.  Wealth-related inequalities of women’s knowledge of cervical cancer screening and service utilisation in 18 resource-constrained countries: evidence from a pooled decomposition analysis , 2020, International Journal for Equity in Health.

[23]  Richard D Moore,et al.  Cervical cancer risk in women living with HIV across four continents: A multicohort study , 2020, International journal of cancer.

[24]  Jie Jiang,et al.  Women’s knowledge of and attitudes toward cervical cancer and cervical cancer screening in Zanzibar, Tanzania: a cross-sectional study , 2019, BMC Cancer.

[25]  J. Kampen,et al.  Knowledge, attitudes and practices of cervical cancer prevention among Zambian women and men , 2019, BMC Public Health.

[26]  A. Amberbir,et al.  Early experiences in integrating cervical cancer screening and treatment into HIV services in Zomba Central Hospital, Malawi , 2018, Malawi medical journal : the journal of Medical Association of Malawi.

[27]  Jane J. Kim,et al.  Evidence‐based policy choices for efficient and equitable cervical cancer screening programs in low‐resource settings , 2017, Cancer medicine.

[28]  S. Resch,et al.  The health and economic impact of scaling cervical cancer prevention in 50 low‐ and lower‐middle‐income countries , 2017, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[29]  S. Yaya,et al.  Wealth, education and urban–rural inequality and maternal healthcare service usage in Malawi , 2016, BMJ Global Health.

[30]  J. Stringer,et al.  Implementation and Operational Research: Age Distribution and Determinants of Invasive Cervical Cancer in a “Screen-and-Treat” Program Integrated With HIV/AIDS Care in Zambia , 2015, Journal of acquired immune deficiency syndromes.

[31]  B. Chi,et al.  Population-Level Scale-Up of Cervical Cancer Prevention Services in a Low-Resource Setting: Development, Implementation, and Evaluation of the Cervical Cancer Prevention Program in Zambia , 2015, PloS one.

[32]  Magnus Lindelow,et al.  Analyzing Health Equity Using Household Survey Data: A Guide to Techniques and Their Implementation , 2007 .

[33]  F. Davidoff,et al.  SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): Revised Publication Guidelines from a Detailed Consensus Process. , 2015, The Permanente journal.

[34]  Faye S. Taxman,et al.  Lessons from the Field , 2024, Cactus and Succulent Journal.

[35]  W. Ross Ethics Approval , 1994, Journal of the Royal College of Physicians of London.