Neural Plasticity and Proliferation in the Generation of Antidepressant Effects: Hippocampal Implication
暂无分享,去创建一个
Elena Castro | F. Pilar-Cuéllar | R. Vidal | Á. Díaz | E. Castro | S. dos Anjos | Jesús Pascual-Brazo | R. Linge | V. Vargas | Helena Blanco | B. Martínez-Villayandre | Á. Pazos | E. Valdizán | Elsa M. Valdizán | Fuencisla Pilar-Cuéllar | Alvaro Díaz | Rebeca Vidal | Severiano dos Anjos | Jesús Pascual-Brazo | Raquel Linge | Veronica Vargas | Helena Blanco | Beatriz Martínez-Villayandre | Ángel Pazos | A. Díaz | Beatriz Martínez-Villayandre
[1] A. Daszuta,et al. Serotonergic reinnervation reverses lesion‐induced decreases in PSA‐nCAM labeling and proliferation of hippocampal cells in adult rats , 2000, Hippocampus.
[2] M. Austin,et al. The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder , 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[3] J. Malberg,et al. Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs. , 2005, Current pharmaceutical design.
[4] Nanxin Li,et al. mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists , 2010, Science.
[5] Jane Sun,et al. Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin. , 2008, Cellular signalling.
[6] H. Praag,et al. Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice , 2010, Brain Research.
[7] Eric J. Nestler,et al. Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus , 2000, The Journal of Neuroscience.
[8] Mikko Sairanen,et al. Brain-Derived Neurotrophic Factor and Antidepressant Drugs Have Different But Coordinated Effects on Neuronal Turnover, Proliferation, and Survival in the Adult Dentate Gyrus , 2005, The Journal of Neuroscience.
[9] Jens Frahm,et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[10] T. Prentice. World Health Report , 2013 .
[11] M. Barrot,et al. Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy , 2008, Biological Psychiatry.
[12] R. Loewith,et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive , 2004, Nature Cell Biology.
[13] J. Price,et al. Low glial numbers in the amygdala in major depressive disorder , 2002, Biological Psychiatry.
[14] Guang Chen,et al. In Vivo Evidence in the Brain for Lithium Inhibition of Glycogen Synthase Kinase-3 , 2004, Neuropsychopharmacology.
[15] R. Duman,et al. Gene Profile of Electroconvulsive Seizures: Induction of Neurotrophic and Angiogenic Factors , 2003, The Journal of Neuroscience.
[16] René Hen,et al. Hippocampal Neurogenesis: Regulation by Stress and Antidepressants , 2006, Biological Psychiatry.
[17] M. Sasvári-Székely,et al. Peripheral vascular endothelial growth factor level is associated with antidepressant treatment response: results of a preliminary study. , 2013, Journal of affective disorders.
[18] J. O'Donnell,et al. Animal models of depression and neuroplasticity: assessing drug action in relation to behavior and neurogenesis. , 2012, Methods in molecular biology.
[19] F. Goodwin,et al. Changes in lymphocyte beta-adrenergic receptors in depression and mania , 1979, Psychiatry Research.
[20] Changsu Han,et al. Low plasma BDNF is associated with suicidal behavior in major depression , 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[21] P. Riederer,et al. Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder , 2003, Journal of Neural Transmission.
[22] C. Stewart,et al. Ketamine pre-treatment dissociates the effects of electroconvulsive stimulation on mossy fibre sprouting and cellular proliferation in the dentate gyrus , 2005, Brain Research.
[23] I. Izquierdo,et al. Phosphorylated cAMP Response Element-Binding Protein as a Molecular Marker of Memory Processing in Rat Hippocampus: Effect of Novelty , 2000, The Journal of Neuroscience.
[24] D. Pandey,et al. A novel 5-HT2A receptor antagonist exhibits antidepressant-like effects in a battery of rodent behavioural assays: Approaching early-onset antidepressants , 2010, Pharmacology Biochemistry and Behavior.
[25] Hui-ling Wang,et al. Brain-derived neurotrophic factor (BDNF) infusion restored astrocytic plasticity in the hippocampus of a rat model of depression , 2011, Neuroscience Letters.
[26] M. Rasenick,et al. Chronic Electroconvulsive Treatment Augments Coupling of the GTP‐Binding Protein Gs to the Catalytic Moiety of Adenylyl Cyclase in a Manner Similar to That Seen with Chronic Antidepressant Drugs , 1991, Journal of neurochemistry.
[27] J. Hagan,et al. The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats , 2008, Neuropharmacology.
[28] D. Melton,et al. A molecular mechanism for the effect of lithium on development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[29] Rajeev Rajendran,et al. 5-HT2A/2C receptor blockade regulates progenitor cell proliferation in the adult rat hippocampus , 2008, Neuroscience Letters.
[30] R. Duman,et al. Role of 5-HT 2 A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus , 1999 .
[31] R. Duman,et al. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice , 2008, Brain Research.
[32] C. Ouimet,et al. Altered dendritic spine density in animal models of depression and in response to antidepressant treatment , 2001, Synapse.
[33] M. Zhuo,et al. Induction of Neuronal Vascular Endothelial Growth Factor Expression by cAMP in the Dentate Gyrus of the Hippocampus Is Required for Antidepressant-Like Behaviors , 2009, The Journal of Neuroscience.
[34] A. Pillai,et al. Long-Term Continuous Corticosterone Treatment Decreases VEGF Receptor-2 Expression in Frontal Cortex , 2011, PloS one.
[35] G. Kempermann. Adult Hippocampal Neurogenesis , 2010 .
[36] B. Roth,et al. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗ ∗ See accompanying Editorial, in this issue. , 1999, Biological Psychiatry.
[37] Nanxin Li,et al. VEGF regulates antidepressant effects of lamotrigine , 2012, European Neuropsychopharmacology.
[38] Yan Chen Shang,et al. Mammalian Target of Rapamycin: Hitting the Bull's-Eye for Neurological Disorders , 2010, Oxidative medicine and cellular longevity.
[39] Y. Lecrubier,et al. Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder , 2011, International clinical psychopharmacology.
[40] Neural plasticity to stress and antidepressant treatment , 1999, Biological Psychiatry.
[41] B. Jacobs,et al. 5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus , 2002, Brain Research.
[42] S. O’Mara,et al. Age-related declines in delayed non-match-to-sample performance (DNMS) are reversed by the novel 5HT6 receptor antagonist SB742457 , 2012, Neuropharmacology.
[43] Chunjie Zhao,et al. Wnt Signaling Mutants Have Decreased Dentate Granule Cell Production and Radial Glial Scaffolding Abnormalities , 2004, The Journal of Neuroscience.
[44] G. Aghajanian,et al. 5-HT2A Receptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex , 1997, The Journal of Neuroscience.
[45] J. Ávila,et al. GSK3 inhibitors and disease. , 2009, Mini reviews in medicinal chemistry.
[46] N. Sonenberg,et al. Upstream and downstream of mTOR. , 2004, Genes & development.
[47] A. Serretti,et al. A glycogen synthase kinase 3-β promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression , 2004, Neuroscience Letters.
[48] A. Schene,et al. Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies , 2007, Molecular Psychiatry.
[49] Susan C. Cook,et al. Chronic stress alters dendritic morphology in rat medial prefrontal cortex. , 2004, Journal of neurobiology.
[50] B. McEwen,et al. Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats , 2011, Psychopharmacology.
[51] M. Takeichi,et al. The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones , 1996, The Journal of cell biology.
[52] P. Houghton,et al. mTORC1 Signaling Can Regulate Growth Factor Activation of p44/42 Mitogen-activated Protein Kinases through Protein Phosphatase 2A* , 2008, Journal of Biological Chemistry.
[53] T. Jay,et al. The Prefrontal Cortex as a Key Target of the Maladaptive Response to Stress , 2007, The Journal of Neuroscience.
[54] A. Placentino,et al. VEGF serum levels in depressed patients during SSRI antidepressant treatment , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[55] M. Joëls,et al. Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible , 2004, The European journal of neuroscience.
[56] P. Salinas,et al. Signalling in neural development: WNTS in the vertebrate nervous system: from patterning to neuronal connectivity , 2005, Nature Reviews Neuroscience.
[57] A. Zangen,et al. Resilience to Chronic Stress Is Mediated by Hippocampal Brain-Derived Neurotrophic Factor , 2011, The Journal of Neuroscience.
[58] L. Acsády,et al. Structural basis of the cholinergic and serotonergic modulation of GABAergic neurons in the hippocampus , 1999, Neurochemistry International.
[59] D. S. Cowen,et al. Age-dependent decline in hippocampal neurogenesis is not altered by chronic treatment with fluoxetine , 2008, Brain Research.
[60] J. Linde,et al. Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders , 2008, Brain Research Bulletin.
[61] J. Azorin,et al. Relation between lymphocyte β-adrenergic responsivity and the severity of depressive disorders , 1994, Biological Psychiatry.
[62] L. San,et al. Altered 5-HT2A and 5-HT4 Postsynaptic Receptors and Their Intracellular Signalling Systems IP3 and cAMP in Brains from Depressed Violent Suicide Victims , 2004, Neuropsychobiology.
[63] E. Nestler,et al. Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens , 2001, The Journal of Neuroscience.
[64] I. Lucki,et al. Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects , 2005, Brain Research.
[65] E. Klein,et al. Antidepressants and prolonged stress in rats modulate CAM-L1, laminin, and pCREB, implicated in neuronal plasticity , 2005, Neurobiology of Disease.
[66] M. Roh,et al. In Vivo Regulation of Glycogen Synthase Kinase-3β (GSK3β) by Serotonergic Activity in Mouse Brain , 2004, Neuropsychopharmacology.
[67] R. Duman,et al. Chronic Antidepressant Administration Alters the Subcellular Distribution of Cyclic AMP‐Dependent Protein Kinase in Rat Frontal Cortex , 1989, Journal of neurochemistry.
[68] G. Wegener,et al. Electroconvulsive seizures stimulate the vegf pathway via mTORC1 , 2012, Synapse.
[69] R. Duman,et al. Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus , 1999, Neuroscience Letters.
[70] M. Millan,et al. Mechanisms Contributing to the Phase-Dependent Regulation of Neurogenesis by the Novel Antidepressant, Agomelatine, in the Adult Rat Hippocampus , 2009, Neuropsychopharmacology.
[71] Hilmar Bading,et al. Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity , 2001, Nature Neuroscience.
[72] B. Czéh,et al. Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex , 2004, Biological Psychiatry.
[73] R. Duman,et al. Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus , 2008, Proceedings of the National Academy of Sciences.
[74] T. Madsen,et al. Chronic electroconvulsive seizure up-regulates β-catenin expression in rat hippocampus: role in adult neurogenesis , 2003, Biological Psychiatry.
[75] E. Nestler,et al. Regulation of Neurogenesis in Adult Mouse Hippocampus by cAMP and the cAMP Response Element-Binding Protein , 2002, The Journal of Neuroscience.
[76] F. Lee,et al. Variant Brain-Derived Neurotrophic Factor Val66Met Polymorphism Alters Vulnerability to Stress and Response to Antidepressants , 2012, The Journal of Neuroscience.
[77] J. Beaulieu,et al. Selective deletion of forebrain glycogen synthase kinase 3β reveals a central role in serotonin-sensitive anxiety and social behaviour , 2012, Philosophical Transactions of the Royal Society B: Biological Sciences.
[78] R. Duman,et al. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[79] L. Devi,et al. Serotonin receptor activation leads to neurite outgrowth and neuronal survival. , 2005, Brain research. Molecular brain research.
[80] F. Holsboer,et al. Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. , 2001, The American journal of pathology.
[81] U. Moens,et al. What turns CREB on? , 2004, Cellular signalling.
[82] T. Mikami,et al. Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice , 2012, Neuroscience.
[83] P. Blier,et al. Pharmacological Blockade of 5-HT7 Receptors as a Putative Fast Acting Antidepressant Strategy , 2011, Neuropsychopharmacology.
[84] A. Wesołowska,et al. Anxiolytic-like and antidepressant-like effects produced by the selective 5-HT6 receptor antagonist SB-258585 after intrahippocampal administration to rats , 2007, Behavioural pharmacology.
[85] K. Lieb,et al. The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: A pilot study , 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[86] M. Riva,et al. Neuronal plasticity: A link between stress and mood disorders , 2009, Psychoneuroendocrinology.
[87] L. Zimmer,et al. 5-HT7 receptor antagonists as a new class of antidepressants. , 2007, Drug news & perspectives.
[88] M. Vilaró,et al. Reduced signal transduction by 5‐HT4 receptors after long‐term venlafaxine treatment in rats , 2010, British journal of pharmacology.
[89] R. Yoshimura,et al. Serum levels of brain‐derived neurotrophic factor in comorbidity of depression and alcohol dependence , 2009, Human psychopharmacology.
[90] J Mao,et al. Axin and Frat1 interact with Dvl and GSK, bridging Dvl to GSK in Wnt‐mediated regulation of LEF‐1 , 1999, The EMBO journal.
[91] J. Morrison,et al. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex , 2004, Neuroscience.
[92] R. Hen,et al. Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal , 2008, Biological Psychiatry.
[93] Yunchun Chen,et al. Citalopram alleviates chronic stress induced depression-like behaviors in rats by activating GSK3β signaling in dorsal hippocampus , 2012, Brain Research.
[94] K. Yoshimoto,et al. Effect of long-lasting serotonin depletion on environmental enrichment-induced neurogenesis in adult rat hippocampus and spatial learning , 2005, Neuroscience.
[95] R. Hen,et al. Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells , 2008, The Journal of Neuroscience.
[96] J. Crespo,et al. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. , 2002, Molecular cell.
[97] J. Sanes,et al. Expression of Multiple Cadherins and Catenins in the Chick Optic Tectum , 1998, Molecular and Cellular Neuroscience.
[98] R. Belmaker,et al. Role of GSK3β in behavioral abnormalities induced by serotonin deficiency , 2008, Proceedings of the National Academy of Sciences.
[99] C. McDougle,et al. Synergistic Action of 5-HT2A Antagonists and Selective Serotonin Reuptake Inhibitors in Neuropsychiatric Disorders , 2003, Neuropsychopharmacology.
[100] J. Sweeney,et al. Subsensitivity of adenylyl cyclase-coupled receptors on mononuclear leukocytes from drug-free inpatients with a major depressive episode , 1997, Biological Psychiatry.
[101] V. Pérez,et al. A double-blind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder , 2011, The international journal of neuropsychopharmacology.
[102] David V Schaffer,et al. PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation , 2007, Developmental neurobiology.
[103] R. Nusse,et al. Convergence of Wnt, ß-Catenin, and Cadherin Pathways , 2004, Science.
[104] E. Castrén,et al. Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects , 2003, The Journal of Neuroscience.
[105] J. Siuciak,et al. Antidepressant-Like Effect of Brain-derived Neurotrophic Factor (BDNF) , 1997, Pharmacology Biochemistry and Behavior.
[106] Jennifer M. Mitchell,et al. Modulation of Anxiety-Like Behavior and Morphine Dependence in CREB-Deficient Mice , 2004, Neuropsychopharmacology.
[107] R. Duman,et al. Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications , 2008, Biological Psychiatry.
[108] Nanxin Li,et al. Signaling pathways underlying the rapid antidepressant actions of ketamine , 2012, Neuropharmacology.
[109] J. Schildkraut,et al. The catecholamine hypothesis of affective disorders: a review of supporting evidence. , 1965, The American journal of psychiatry.
[110] J. Blendy. The Role of CREB in Depression and Antidepressant Treatment , 2006, Biological Psychiatry.
[111] B. Tabakoff,et al. Forskolin-stimulated platelet adenylyl cyclase activity is lower in persons with major depression , 1997, Biological Psychiatry.
[112] S. Henriksen,et al. 5-HT7 Receptor Inhibition and Inactivation Induce Antidepressantlike Behavior and Sleep Pattern , 2005, Biological Psychiatry.
[113] R. Duman,et al. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[114] R. Nosheny,et al. Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex , 2008, Neuroscience Letters.
[115] E. Stamatakou,et al. Wnt Regulates Axon Behavior through Changes in Microtubule Growth Directionality: A New Role for Adenomatous Polyposis Coli , 2008, The Journal of Neuroscience.
[116] Changlian Zhu,et al. Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain , 2012, Molecular and Cellular Neuroscience.
[117] B. Doble,et al. GSK-3 is a master regulator of neural progenitor homeostasis , 2009, Nature Neuroscience.
[118] T. Hagg,et al. Serotonin 1A receptor agonist increases species- and region-selective adult CNS proliferation, but not through CNTF , 2012, Neuropharmacology.
[119] J. Guan,et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. , 2009, Molecular biology of the cell.
[120] J. Davis,et al. Beta adrenergic receptor function in depression and the effect of antidepressant drugs. , 2009, Acta pharmacologica et toxicologica.
[121] Margit Burmeister,et al. A BDNF Coding Variant is Associated with the NEO Personality Inventory Domain Neuroticism, a Risk Factor for Depression , 2003, Neuropsychopharmacology.
[122] R. Neve,et al. Effects of cyclic adenosine monophosphate response element binding protein overexpression in the basolateral amygdala on behavioral models of depression and anxiety , 2004, Biological Psychiatry.
[123] Kenji Hashimoto,et al. Brain‐derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions , 2010, Psychiatry and clinical neurosciences.
[124] J Galceran,et al. Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. , 2000, Development.
[125] Abbas F. Sadikot,et al. Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action , 2007, Neuron.
[126] Jordan Grafman,et al. The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex , 2009, Behavioural Brain Research.
[127] Bruce S. McEwen,et al. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons , 1992, Brain Research.
[128] J. Price,et al. Neurocircuitry of Mood Disorders , 2010, Neuropsychopharmacology.
[129] Y. Ahn,et al. The effect of MK-801 on mTOR/p70S6K and translation-related proteins in rat frontal cortex , 2008, Neuroscience Letters.
[130] L. Parada,et al. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF , 2009, Molecular Neurodegeneration.
[131] P. Arlotta,et al. Conditional Knock-Out of β-Catenin in Postnatal-Born Dentate Gyrus Granule Neurons Results in Dendritic Malformation , 2007, The Journal of Neuroscience.
[132] G. Debonnel,et al. Selective Serotonin Reuptake Inhibitors Potentiate the Rapid Antidepressant-Like Effects of Serotonin4 Receptor Agonists in the Rat , 2010, PloS one.
[133] T. Ban. Pharmacotherapy of depression: a historical analysis , 2001, Journal of Neural Transmission.
[134] Abraham Weizman,et al. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on β-catenin in mouse hippocampus , 2004, Biological Psychiatry.
[135] M. J. Kim,et al. Fluoxetine enhances cell proliferation and prevents apoptosis in dentate gyrus of maternally separated rats , 2001, Molecular Psychiatry.
[136] G. Merlo,et al. Activation of the Wnt–βCatenin Pathway in a Cell Population on the Surface of the Forebrain Is Essential for the Establishment of Olfactory Axon Connections , 2007, The Journal of Neuroscience.
[137] F. Taneli,et al. Effect of treatment on serum brain–derived neurotrophic factor levels in depressed patients , 2005, European Archives of Psychiatry and Clinical Neuroscience.
[138] Jörg Stappert,et al. β‐catenin is a target for the ubiquitin–proteasome pathway , 1997 .
[139] W. Birchmeier,et al. Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly , 2003, Neuron.
[140] R. Hen,et al. Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants , 2003, Science.
[141] C. Sandi,et al. Role of the Amygdala in Antidepressant Effects on Hippocampal Cell Proliferation and Survival and on Depression-like Behavior in the Rat , 2010, PloS one.
[142] R. Hu. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) , 2003 .
[143] R. Duman,et al. Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment , 2006, Hippocampus.
[144] A. Frasch,et al. Regulation of Hippocampal Gene Expression Is Conserved in Two Species Subjected to Different Stressors and Antidepressant Treatments , 2006, Biological Psychiatry.
[145] Zhen Yan,et al. The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission , 2011, Nature Reviews Neuroscience.
[146] B. Luikart,et al. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment , 2008, Neuron.
[147] H. Manji,et al. Generation and behavioral characterization of β-catenin forebrain-specific conditional knock-out mice , 2008, Behavioural Brain Research.
[148] J. Herbert,et al. The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids , 2005, Neuroscience.
[149] M. Galloway,et al. Repeated Unpredictable Stress and Antidepressants Differentially Regulate Expression of the Bcl-2 Family of Apoptotic Genes in Rat Cortical, Hippocampal, and Limbic Brain Structures , 2008, Neuropsychopharmacology.
[150] Lauren M. Bylsma,et al. A meta-analysis of emotional reactivity in major depressive disorder. , 2008, Clinical psychology review.
[151] E. Domenici,et al. Chronic Social Stress Inhibits Cell Proliferation in the Adult Medial Prefrontal Cortex: Hemispheric Asymmetry and Reversal by Fluoxetine Treatment , 2007, Neuropsychopharmacology.
[152] M. Takeichi,et al. Cadherin Regulates Dendritic Spine Morphogenesis , 2002, Neuron.
[153] A. Bortolozzi,et al. RNAi-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis , 2013, Translational Psychiatry.
[154] J. Heitman,et al. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast , 1991, Science.
[155] G. MacQueen,et al. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression , 1998, The Lancet.
[156] R. Malenka,et al. Beta-catenin is critical for dendritic morphogenesis. , 2003, Nature neuroscience.
[157] A. Wesołowska,et al. The selective 5-HT(6) receptor antagonist SB-399885 enhances anti-immobility action of antidepressants in rats. , 2008, European journal of pharmacology.
[158] A. Eisch,et al. Adult neurogenesis: implications for psychiatry. , 2002, Progress in brain research.
[159] H. Manji,et al. β-Catenin Overexpression in the Mouse Brain Phenocopies Lithium-Sensitive Behaviors , 2007, Neuropsychopharmacology.
[160] A. Caspi,et al. Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene , 2003, Science.
[161] James C. Overholser,et al. Cellular changes in the postmortem hippocampus in major depression , 2004, Biological Psychiatry.
[162] Paul J Carlson,et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. , 2006, Archives of general psychiatry.
[163] Shaohui Wang,et al. Mammalian target of rapamycin Hitting the bull ’ seye for neurological disorders , 2014 .
[164] S. Russo,et al. Structural and synaptic plasticity in stress-related disorders , 2011, Reviews in the neurosciences.
[165] Han-Ting Zhang. Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs. , 2009, Current pharmaceutical design.
[166] T. Force,et al. Activation of β-catenin Signaling Pathways by Classical G-Protein-Coupled Receptors: Mechanisms and Consequences in Cycling and Non-cycling Cells , 2006, Cell cycle.
[167] Harley I Kornblum,et al. Endogenous Wnt Signaling Maintains Neural Progenitor Cell Potency , 2009, Stem cells.
[168] R. Shelton,et al. Noradrenergic antidepressants: does chronic treatment increase or decrease nuclear CREB-P? , 2002, Journal of Neural Transmission.
[169] Guang Chen,et al. Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors , 2008, Biological Psychiatry.
[170] T. Palmer,et al. Vascular niche for adult hippocampal neurogenesis , 2000, The Journal of comparative neurology.
[171] E. Nestler,et al. The many faces of CREB , 2005, Trends in Neurosciences.
[172] M. Joëls,et al. Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression , 2005, The European journal of neuroscience.
[173] M. Barrot,et al. Essential role of brain-derived neurotrophic factor in adult hippocampal function. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[174] T. Perera,et al. Cognitive Role of Neurogenesis in Depression and Antidepressant Treatment , 2008, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[175] A. Wesołowska. Potential role of the 5-HT_6 receptor in depression and anxiety: an overview of preclinical data , 2010, Pharmacological reports : PR.
[176] T. Madsen,et al. Electroconvulsive seizure restores neurogenesis and hippocampus‐dependent fear memory after disruption by irradiation , 2008, The European journal of neuroscience.
[177] Ping Wu,et al. Hippocampal CA3 calcineurin activity participates in depressive‐like behavior in rats , 2011, Journal of neurochemistry.
[178] R. Mostany,et al. Long‐term treatment with fluoxetine induces desensitization of 5‐HT4 receptor‐dependent signalling and functionality in rat brain , 2009, Journal of neurochemistry.
[179] K. Neve,et al. Sensitization of adenylate cyclase by Gαi/o-coupled receptors , 2005 .
[180] H. Delacroix,et al. Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT1A and 5-HT1B receptors disruption in mice , 2012, Neuroscience Letters.
[181] J. Price,et al. Glial reduction in the subgenual prefrontal cortex in mood disorders. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[182] A. L. Garcia-Garcia,et al. Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex , 2011, European Neuropsychopharmacology.
[183] R. Jope,et al. Blocked Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3α/β Impairs In Vivo Neural Precursor Cell Proliferation , 2009, Biological Psychiatry.
[184] E. Nestler,et al. A molecular and cellular theory of depression. , 1997, Archives of general psychiatry.
[185] Ronald S Duman,et al. Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment , 2003, Neuropsychopharmacology.
[186] Nanxin Li,et al. Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress , 2012, Proceedings of the National Academy of Sciences.
[187] J. Guimón,et al. Cyclic AMP-mediated signaling components are upregulated in the prefrontal cortex of depressed suicide victims , 2001, Brain Research.
[188] H. Yokoo,et al. Lithium: potential therapeutics against acute brain injuries and chronic neurodegenerative diseases. , 2005, Journal of pharmacological sciences.
[189] J. Sweeney,et al. Blunted beta-adrenergic responsivity of peripheral blood mononuclear cells in endogenous depression. Isoproterenol dose-response studies. , 1988, Archives of general psychiatry.
[190] M. Austin,et al. Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stress , 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[191] Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR signaling pathway , 2012, Psychopharmacology.
[192] D. Zald,et al. Reconsidering anhedonia in depression: Lessons from translational neuroscience , 2011, Neuroscience & Biobehavioral Reviews.
[193] J. Csernansky,et al. Hippocampal atrophy in recurrent major depression. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[194] C. Pittenger,et al. Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms , 2008, Neuropsychopharmacology.
[195] J. Lucas,et al. Spatial learning deficit in transgenic mice that conditionally over‐express GSK‐3β in the brain but do not form tau filaments , 2002, Journal of neurochemistry.
[196] D. S. Cowen,et al. Serotonin and neuronal growth factors – a convergence of signaling pathways , 2007, Journal of neurochemistry.
[197] R. Duman,et al. Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression , 2002, The Journal of Neuroscience.
[198] F. Pilar-Cuéllar,et al. Subchronic treatment with fluoxetine and ketanserin increases hippocampal brain‐derived neurotrophic factor, β‐catenin and antidepressant‐like effects , 2012, British journal of pharmacology.
[199] K. Maiese,et al. Vital elements of the Wnt-Frizzled signaling pathway in the nervous system. , 2005, Current neurovascular research.
[200] J. Kunz,et al. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. , 1994, Molecular biology of the cell.
[201] R. Moon,et al. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. , 1996, Genes & development.
[202] G. MacQueen,et al. G Protein‐Coupled Cyclic AMP Signaling in Postmortem Brain of Subjects with Mood Disorders , 1999, Journal of neurochemistry.
[203] E. Klann,et al. mTOR signaling: At the crossroads of plasticity, memory and disease , 2010, Trends in Neurosciences.
[204] Rene Hen,et al. Adult hippocampal neurogenesis in depression , 2007, Nature Neuroscience.
[205] Y. Hata,et al. Interaction of Synaptic Scaffolding Molecule and β-Catenin , 2002, The Journal of Neuroscience.
[206] Fred H. Gage,et al. Wnt signalling regulates adult hippocampal neurogenesis , 2005, Nature.
[207] J. Kunz,et al. Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression , 1993, Cell.
[208] P. Roig,et al. Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin‐induced diabetic mice: reversion by antidepressant treatment , 2006, The European journal of neuroscience.
[209] R. Neve,et al. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect , 2001, Biological Psychiatry.
[210] M. Egan,et al. The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function , 2003, Cell.
[211] F. Pilar-Cuéllar,et al. Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT₄ receptor agonist RS67333. , 2012, The international journal of neuropsychopharmacology.
[212] P. Penzes,et al. Dendritic spine pathology in neuropsychiatric disorders , 2011, Nature Neuroscience.
[213] T. Maeda,et al. Nutrient-dependent Multimerization of the Mammalian Target of Rapamycin through the N-terminal HEAT Repeat Region* , 2006, Journal of Biological Chemistry.
[214] H. Okano,et al. β‐Catenin Signaling Promotes Proliferation of Progenitor Cells in the Adult Mouse Subventricular Zone , 2007, Stem cells.
[215] Ronald S Duman,et al. Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models , 2011, Neuropsychopharmacology.
[216] H. Manji,et al. Signaling networks in the pathophysiology and treatment of mood disorders. , 2002, Journal of psychosomatic research.
[217] J. Stephenson. World health report. , 2004, Lancet.
[218] Grigori Enikolopov,et al. Fluoxetine targets early progenitor cells in the adult brain. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[219] M. Pedersen,et al. Decreased Hippocampal Neurogenesis Following Olfactory Bulbectomy is Reversed by Repeated Citalopram Administration , 2006, Cellular and Molecular Neurobiology.
[220] F. Drago,et al. Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: Behavioral and neurochemical studies in rats , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[221] B. Franke,et al. Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity , 2010, Molecular Psychiatry.
[222] M. Popoli,et al. Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview , 2006, Pharmacological Reviews.
[223] Á. Pazos,et al. Adenylate cyclase activity in postmortem brain of suicide subjects: reduced response to β-adrenergic stimulation , 2003, Biological Psychiatry.
[224] R. Jope,et al. Mood stabilizers, glycogen synthase kinase-3β and cell survival , 2002, Molecular Psychiatry.
[225] H. Braak,et al. Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. , 2003, The American journal of pathology.
[226] Andrew Lemire,et al. Electroconvulsive Seizures Regulate Gene Expression of Distinct Neurotrophic Signaling Pathways , 2004, The Journal of Neuroscience.
[227] R. Nusse,et al. Convergence of Wnt, beta-catenin, and cadherin pathways. , 2004, Science.
[228] Thomas Michaelis,et al. Alterations of neuroplasticity in depression: the hippocampus and beyond , 2004, European Neuropsychopharmacology.
[229] R. Duman,et al. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat , 2004, Biological Psychiatry.
[230] R. Nusse,et al. The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.
[231] J. Woodgett,et al. Glycogen Synthase Kinase-3β Haploinsufficiency Mimics the Behavioral and Molecular Effects of Lithium , 2004, The Journal of Neuroscience.
[232] R. Duman,et al. mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade. , 2012, The international journal of neuropsychopharmacology.
[233] Jing Wang,et al. Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex. , 2008, Learning & memory.
[234] J. Sweatt,et al. Deficiency in the Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3 Increases Sensitivity to Mood Disturbances , 2010, Neuropsychopharmacology.
[235] M. Drew,et al. Dentate gyrus neurogenesis and depression. , 2007, Progress in brain research.
[236] Christophe Bernard,et al. Vulnerability to Depression: From Brain Neuroplasticity to Identification of Biomarkers , 2011, The Journal of Neuroscience.
[237] Adam M. Campbell,et al. Preclinical research on stress, memory, and the brain in the development of pharmacotherapy for depression , 2004, European Neuropsychopharmacology.
[238] L. Staib,et al. Hippocampal volume reduction in major depression. , 2000, The American journal of psychiatry.
[239] A. Malafosse,et al. Protein levels of β-catenin and activation state of glycogen synthase kinase-3β in major depression. A study with postmortem prefrontal cortex. , 2012, Journal of affective disorders.
[240] D. Ginty,et al. Function and Regulation of CREB Family Transcription Factors in the Nervous System , 2002, Neuron.
[241] S. Mathew,et al. Glutamate modulators as novel interventions for mood disorders. , 2005, Revista brasileira de psiquiatria.
[242] J. Price,et al. Neural circuits underlying the pathophysiology of mood disorders , 2012, Trends in Cognitive Sciences.
[243] R. Mostany,et al. A role for nuclear β-catenin in SNRI antidepressant-induced hippocampal cell proliferation , 2008, Neuropharmacology.
[244] E. Smeraldi,et al. Gene-gene interaction of glycogen synthase kinase 3-β and serotonin transporter on human antidepressant response to sleep deprivation. , 2012, Journal of affective disorders.
[245] J. Cryan,et al. Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: A role for hippocampal cell proliferation , 2013, Neuroscience.
[246] Yogesh K. Dwivedi,et al. Differential and brain region-specific regulation of Rap-1 and Epac in depressed suicide victims. , 2006, Archives of general psychiatry.
[247] H. Manji,et al. The Mood‐Stabilizing Agent Valproate Inhibits the Activity of Glycogen Synthase Kinase‐3 , 2000, Journal of neurochemistry.
[248] C. Nemeroff,et al. Lithium, but Not Fluoxetine or the Corticotropin-Releasing Factor Receptor 1 Receptor Antagonist R121919, Increases Cell Proliferation in the Adult Dentate Gyrus , 2011, Journal of Pharmacology and Experimental Therapeutics.
[249] A. Gingras,et al. A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[250] C. Siao,et al. Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior , 2006, Science.
[251] R. Duman,et al. A Neurotrophic Model for Stress-Related Mood Disorders , 2006, Biological Psychiatry.
[252] Nobumasa Kato,et al. Gene expression profiling of major depression and suicide in the prefrontal cortex of postmortem brains , 2008, Neuroscience Research.
[253] P. Hedlund,et al. The 5-HT7 receptor is involved in allocentric spatial memory information processing , 2009, Behavioural Brain Research.
[254] M. Héry,et al. Serotonin-Induced Increases in Adult Cell Proliferation and Neurogenesis are Mediated Through Different and Common 5-HT Receptor Subtypes in the Dentate Gyrus and the Subventricular Zone , 2004, Neuropsychopharmacology.
[255] S. Stahl. The serotonin-7 receptor as a novel therapeutic target. , 2010, The Journal of clinical psychiatry.
[256] J. Thome,et al. cAMP Response Element-Mediated Gene Transcription Is Upregulated by Chronic Antidepressant Treatment , 2000, The Journal of Neuroscience.
[257] Eric J. Nestler,et al. New approaches to antidepressant drug discovery: beyond monoamines , 2006, Nature Reviews Neuroscience.
[258] N. Sonenberg,et al. Mechanisms governing the control of mRNA translation , 2010, Physical biology.
[259] Zhi-qiang Zhou,et al. Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test , 2013, Upsala journal of medical sciences.
[260] R. Vidal,et al. Long-Term Fluoxetine Treatment Modulates Cannabinoid Type 1 Receptor-Mediated Inhibition of Adenylyl Cyclase in the Rat Prefrontal Cortex through 5-Hydroxytryptamine1A Receptor-Dependent Mechanisms , 2010, Molecular Pharmacology.
[261] E. Palazidou. The neurobiology of depression. , 2012, British medical bulletin.
[262] A. Wesołowska,et al. Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression , 2007, Neuropharmacology.
[263] G. Griebel,et al. Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression , 2004, Molecular Psychiatry.
[264] C. Bramham,et al. Chronic Fluoxetine Treatment Induces Brain Region-Specific Upregulation of Genes Associated with BDNF-Induced Long-Term Potentiation , 2007, Neural plasticity.
[265] Shao-Jun Tang,et al. Roles of Glutamate Receptors and the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Activity-dependent Dendritic Protein Synthesis in Hippocampal Neurons* , 2006, Journal of Biological Chemistry.
[266] A. Shaywitz,et al. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. , 1999, Annual review of biochemistry.