Microangiographic Changes in the Traumatized Brain

The increased use of motorized transportation has caused a sharp rise in the incidence of acute head trauma. The treatment of serious acute head trauma is often unrewarding, and the reasons for poor response to treatment in many instances are not well understood (BENDER 1960, CLARKE & ROWBOTHAM 1963, HUNTER 1960). The purpose of this investigation was to determine if any changes might be demonstrated in the microscopic vessels in the traumatized brain by microangiographic techniques. Human autopsy material was used initially, but because of lack of control over the time interval between death and autopsy and an incomplete knowledge of the exact nature and amplitude of the injuring force, it was decided to concentrate our work on laboratory animals which could be studied under optimal controlled conditions.

[1]  Rockoff Sd,et al.  EXPERIMENTAL HEAD TRAUMA. CEREBRAL ANGIOGRAPHIC OBSERVATIONS IN THE EARLY POST-TRAUMATIC PERIOD. , 1964 .

[2]  A. Margulis,et al.  MICROANGIOGRAPHY IN EXPERIMENTAL CEREBRAL EDEMA IN RATS. , 1964, Radiology.

[3]  A. Ommaya,et al.  EXPERIMENTAL HEAD TRAUMA. CEREBRAL ANGIOGRAPHIC OBSERVATIONS IN THE EARLY POST-TRAUMATIC PERIOD. , 1964, The American journal of roentgenology, radium therapy, and nuclear medicine.

[4]  G. F. Rowbotham,et al.  The Management of Head Injuries , 1963, Postgraduate medical journal.

[5]  R. Sundström,et al.  Local and General Spasm in the Internal Carotid System following Trauma , 1963 .

[6]  G. Gaist,et al.  Angiography in Traumatic Cerebral Lacerations with Special Regard to Some Less Common Aspects , 1963, Acta radiologica: therapy, physics, biology.

[7]  J. Innes,et al.  Craigie's Neuroanatomy of the rat. , 1963 .

[8]  U. SAW NYUNT.  Management of head injuries. , 1961, Burma medical journal.

[9]  A. Hunter.  Basic Considerations in the Conservative Care of Head Injuries , 1960 .

[10]  M. B. Bender.  Recovery from subdural hematoma without surgery. , 1960, Journal of the Mount Sinai Hospital, New York.

[11]  H. W. Magoun,et al.  Functional and Structural Changes in the Monkey's Brain During and After Concussion* , 1945 .

[12]  Joseph P. Evans,et al.  Histologic Studies of the Brain Following Head Trauma: IV. Late Changes: Atrophic Sclerosis of the White Matter , 1944 .

[13]  F. Echlin.  VASOSPASM AND FOCAL CEREBRAL ISCHEMIA: AN EXPERIMENTAL STUDY , 1942 .

[14]  W. Ritchie Russell,et al.  Experimental cerebral concussion , 1940, The Journal of physiology.

[15]  H. Florey.  MICROSCOPICAL OBSERVATIONS ON THE CIRCULATION OF THE BLOOD IN THE CEREBRAL CORTEX , 1925 .