First National Workshop on Antibiotic Resistance in Cambodia: Phnom Penh, Cambodia, 16-18 November 2011.

The First National Workshop on Antibiotic Resistance in Cambodia was organised by the Cambodian Ministry of Health with support from several national and international partner institutions. It brought together policy-makers, clinicians, pharmacists, laboratory technicians and other professionals dealing with the problems of bacterial infection and antibiotic resistance across the country. Antibiotic resistance data from starting up and experienced laboratories were presented, showing high rates of resistance in key pathogens to most antibiotics currently available in Cambodia, e.g. 70-90% multidrug resistance and 70-80% decreased ciprofloxacin susceptibility in Salmonella enterica serovar Typhi, 20-40% meticillin resistance rates in Staphylococcus aureus and 30-50% extended-spectrum β-lactamase production in Escherichia coli. A five-point plan was discussed, which included initiatives from government and non-governmental partners, focusing on rational prescribing, clinical practice guidelines, improved laboratory services, infection prevention and enhanced education at all levels. Implementation, however challenging, is a priority given the high levels of resistance seen in key pathogens and the overall health needs in the country.

[1]  E. Petersen Emerging infectious disease. , 1996, Archives of internal medicine.

[2]  N. Day,et al.  Emergence of Community-Associated Methicillin-Resistant Staphylococcus aureus Associated with Pediatric Infection in Cambodia , 2009, PloS one.

[3]  A. Sharma Antimicrobial resistance: no action today, no cure tomorrow. , 2011, Indian journal of medical microbiology.

[4]  L. Lynen,et al.  Bloodstream Infection among Adults in Phnom Penh, Cambodia: Key Pathogens and Resistance Patterns , 2013, PloS one.

[5]  Cathy A Petti,et al.  Laboratory medicine in Africa: a barrier to effective health care. , 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[6]  Tikki Pang,et al.  A study of typhoid fever in five Asian countries: disease burden and implications for controls. , 2008, Bulletin of the World Health Organization.

[7]  D. Socheat,et al.  Counterfeit and substandard antimalarial drugs in Cambodia. , 2006, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[8]  F. Ariey,et al.  CTX-M β-Lactamases in Escherichia coli from Community-acquired Urinary Tract Infections, Cambodia , 2009, Emerging infectious diseases.

[9]  I. Okeke Divining without Seeds: The Case for Strengthening Laboratory Medicine in Africa , 2011 .

[10]  P. Blair,et al.  Emergence of multidrug-resistant Salmonella enterica serovar Typhi with reduced susceptibility to fluoroquinolones in Cambodia. , 2010, Diagnostic microbiology and infectious disease.