1 Self-Sensing Surface Plasmon Resonance for the Detection of Metallic Nanoparticles

Surface plasmon resonance (SPR) is an established technique for label free sensing of bio-molecular species, including time-dependent reaction analysis. Unlike previous research by other workers, who have used gold or silver nanoparticles to enhance sensitivity by inducing LSPR, this study involves the theoretical development of a Localised SPR (LSPR) system where a glass prism is considered with multilayer films to enable the detection of metallic nanoparticles. Silver nanoparticles with a volume concentration 0.25 % can be clearly detected from both amplitude and phase, according to the results of these simulations. The model presented is rigorous in that it accounts for the effect of the Cr or Ti adhesion layers together with a graphene layer at the metal-sensing interface. This enables the direct detection of the presence of nanoparticles from their plasmonic amplitude and phase (self-sensing). Our model also demonstrates that the sensitivity of the sensors can be significantly improved with the introduction of graphene layers.

[1]  S. Maier.  Plasmonics: Fundamentals and Applications , 2007 .

[2]  R. Karlsson,et al.  Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors. , 1997, Journal of immunological methods.

[3]  Kyung Min Byun,et al.  Investigation on an application of silver substrates for sensitive surface plasmon resonance imaging detection. , 2010, Journal of the Optical Society of America. A, Optics, image science, and vision.

[4]  Rui Hu,et al.  Nanoparticle enhanced surface plasmon resonance biosensing: application of gold nanorods. , 2009, Optics express.

[5]  C. Du,et al.  Localized surface plasmon resonance-based hybrid Au–Ag nanoparticles for detection of Staphylococcus aureus enterotoxin B , 2009 .

[6]  Dakai Liang,et al.  Applications of optical fiber SPR sensor for measuring of temperature and concentration of liquids , 2005, International Conference on Optical Fibre Sensors.

[7]  Richard P Van Duyne,et al.  Metal-organic framework thin film for enhanced localized surface plasmon resonance gas sensing. , 2010, Analytical chemistry.

[8]  Xiaowei Guo.  Surface plasmon resonance based biosensor technique: A review , 2012, Journal of biophotonics.

[9]  Xiaohua Huang,et al.  Noble metals on the nanoscale: optical and photothermal properties and some applications in imaging, sensing, biology, and medicine. , 2008, Accounts of chemical research.

[10]  Tadatsugu Minami,et al.  Present status of transparent conducting oxide thin-film development for Indium-Tin-Oxide (ITO) substitutes , 2008 .

[11]  Craig A. Poland,et al.  Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. , 2008, Nature nanotechnology.

[12]  U. Krull,et al.  Localized surface plasmon resonance: nanostructures, bioassays and biosensing--a review. , 2011, Analytica chimica acta.

[13]  Rui Hu,et al.  Size dependence of Au NP-enhanced surface plasmon resonance based on differential phase measurement , 2013 .

[14]  E. Kretschmann,et al.  Notizen: Radiative Decay of Non Radiative Surface Plasmons Excited by Light , 1968 .

[15]  Anshi Xu,et al.  Fabry-Pérot-based surface plasmon resonance sensors. , 2012, Optics letters.

[16]  H. Ming,et al.  Review of surface plasmon resonance and localized surface plasmon resonance sensor , 2012 .

[17]  E. Palik.  Handbook of Optical Constants of Solids , 1997 .

[18]  G. Palleschi,et al.  Enzyme inhibition-based biosensors for food safety and environmental monitoring. , 2006, Biosensors & bioelectronics.

[19]  S. Sreedhar,et al.  Silver nano-entities through ultrafast double ablation in aqueous media for surface enhanced Raman scattering and photonics applications , 2013 .

[20]  Stefano Borini,et al.  Optical constants of graphene layers in the visible range , 2009 .

[21]  D. Roy,et al.  Surface Plasmon Resonance Studies of Gold and Silver Nanoparticles Linked to Gold and Silver Substrates by 2-Aminoethanethiol and 1,6-Hexanedithiol , 2001 .

[22]  Chunhai Fan,et al.  Graphene on Au(111): a highly conductive material with excellent adsorption properties for high-resolution bio/nanodetection and identification. , 2010, Chemphyschem : a European journal of chemical physics and physical chemistry.

[23]  Jiří Homola,et al.  Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison , 1999 .

[24]  R. Schasfoort,et al.  Handbook of surface plasmon resonance , 2008 .

[25]  N. Miura,et al.  Recent advancements in surface plasmon resonance immunosensors for detection of small molecules of biomedical, food and environmental interest , 2007 .

[26]  Jeffrey N. Anker,et al.  Gas sensing with high-resolution localized surface plasmon resonance spectroscopy. , 2010, Journal of the American Chemical Society.

[27]  Andre K. Geim,et al.  Electric Field Effect in Atomically Thin Carbon Films , 2004, Science.

[28]  BIOSENSORS BASED ON SURFACE PLASMON RESONANCE PHENOMENON: A THEORETICAL REVIEW , 2011 .

[29]  Agustín Costa-García,et al.  Recent Advances in Electrochemical Enzyme Immunoassays , 2005 .

[30]  M. Maglione,et al.  Guided-wave electro-optic characterization of BaTiO3 thin films using the prism coupling technique. , 2013, Optics letters.

[31]  A. Rasooly,et al.  Biosensors and Biodetection , 2017, Methods in Molecular Biology.

[32]  Frances S. Ligler,et al.  Optical biosensors : today and tomorrow , 2008 .

[33]  Yukari Sato,et al.  Mediatorless Superoxide Dismutase Sensors Using Cytochrome c‐Modified Electrodes: Xanthine Oxidase Incorporated Polyion Complex Membrane for Enhanced Activity and In Vivo Analysis , 2001 .

[34]  Jaeyoung Lee,et al.  Nanoparticle-enhanced surface plasmon resonance detection of proteins at attomolar concentrations: comparing different nanoparticle shapes and sizes. , 2012, Analytical chemistry.