Mutations in the Exocyst Component Sec5 Disrupt Neuronal Membrane Traffic, but Neurotransmitter Release Persists

[1]  Y. Kidokoro,et al.  Longitudinal body wall muscles are electrically coupled across the segmental boundary in the third instar larva ofDrosophila melanogaster , 1996, Invertebrate Neuroscience.

[2]  A. Régnier-Vigouroux,et al.  Biogenesis of small synaptic vesicles and synaptic-like microvesicles , 2004, Neurochemical Research.

[3]  Kendal Broadie,et al.  Living synaptic vesicle marker: Synaptotagmin‐GFP , 2002, Genesis.

[4]  C. Rossé,et al.  The exocyst is a Ral effector complex , 2002, Nature Cell Biology.

[5]  C. Yeaman,et al.  Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells , 2001, The Journal of cell biology.

[6]  Benjamin H. White,et al.  A conditional tissue-specific transgene expression system using inducible GAL4 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[7]  Irving E. Vega,et al.  The Exocyst Complex Associates with Microtubules to Mediate Vesicle Targeting and Neurite Outgrowth , 2001, The Journal of Neuroscience.

[8]  V. Malhotra,et al.  Protein Kinase D Regulates the Fission of Cell Surface Destined Transport Carriers from the Trans-Golgi Network , 2001, Cell.

[9]  W. Trimble,et al.  SNARE proteins contribute to calcium cooperativity of synaptic transmission. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[10]  P. Novick,et al.  Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. , 2000, Molecular biology of the cell.

[11]  Thomas C. Südhof,et al.  The Synaptic VesicleCycle Revisited , 2000, Neuron.

[12]  P. Novick,et al.  Ordering the Final Events in Yeast Exocytosis , 2000, The Journal of cell biology.

[13]  T. Südhof,et al.  The synaptic vesicle cycle revisited. , 2000, Neuron.

[14]  R. Scheller,et al.  Mechanisms of synaptic vesicle exocytosis. , 2000, Annual review of cell and developmental biology.

[15]  P. Novick,et al.  Exo84p Is an Exocyst Protein Essential for Secretion* , 1999, The Journal of Biological Chemistry.

[16]  T. Schwarz,et al.  A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. , 1999, Genetics.

[17]  P. Novick,et al.  The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis , 1999, The EMBO journal.

[18]  R. Scheller,et al.  The sec6/8 Complex Is Located at Neurite Outgrowth and Axonal Synapse-Assembly Domains , 1999, The Journal of Neuroscience.

[19]  V. Olkkonen,et al.  SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[20]  W. Huttner,et al.  Synaptic vesicle biogenesis. , 1999, Annual review of cell and developmental biology.

[21]  P. Novick,et al.  Spatial Regulation of Exocytosis: Lessons from Yeast , 1998, The Journal of cell biology.

[22]  R. Scheller,et al.  Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells , 1998, Cell.

[23]  G. Banker,et al.  The Polarized Sorting of Membrane Proteins Expressed in Cultured Hippocampal Neurons Using Viral Vectors , 1998, Neuron.

[24]  Peter Novick,et al.  Sec3p Is a Spatial Landmark for Polarized Secretion in Budding Yeast , 1998, Cell.

[25]  R. Scheller,et al.  Subunit structure of the mammalian exocyst complex. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Philippe Soriano,et al.  The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse. , 1997, Developmental biology.

[27]  P. Novick,et al.  Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae. , 1997, Molecular biology of the cell.

[28]  David R. Kaplan,et al.  Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.

[29]  R. Scheller,et al.  The Mammalian Brain rsec6/8 Complex , 1996, Neuron.

[30]  N. Perrimon,et al.  The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. , 1996, Genetics.

[31]  Richard D Fetter,et al.  Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. I. Fasciclin II Controls Synaptic Stabilization and Growth , 1996, Neuron.

[32]  R. Scheller,et al.  Synaptic vesicle biogenesis, docking, and fusion: a molecular description. , 1996, Physiological reviews.

[33]  B. S. Baker,et al.  The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal. , 1995, Development.

[34]  P. Novick,et al.  Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae , 1995, The Journal of cell biology.

[35]  A. Craig,et al.  Preferential addition of newly synthesized membrane protein at axonal growth cones , 1995, Nature.

[36]  J. Rothman,et al.  Mechanisms of intracellular protein transport , 1994, Nature.

[37]  P. De Camilli,et al.  Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons , 1992, The Journal of cell biology.

[38]  K. Simons,et al.  Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture , 1990, Cell.

[39]  P. Novick,et al.  The Sec15 protein responds to the function of the GTP binding protein, Sec4, to control vesicular traffic in yeast , 1989, The Journal of cell biology.

[40]  R. Kelly,et al.  Constitutive and regulated secretion of proteins. , 1987, Annual review of cell biology.

[41]  M. Poo,et al.  Dissociated neurons from normal and mutant Drosophila larval central nervous system in cell culture , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[42]  R. Schekman,et al.  Order of events in the yeast secretory pathway , 1981, Cell.

[43]  R. Schekman,et al.  Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway , 1980, Cell.

[44]  D. Bray,et al.  Surface movements during the growth of single explanted neurons. , 1970, Proceedings of the National Academy of Sciences of the United States of America.