CSTA plays a role in osteoclast formation and bone resorption by mediating the DAP12/TREM2 pathway.
暂无分享,去创建一个
[1] K. Izumi,et al. Testosterone and Bone Health in Men: A Narrative Review , 2021, Journal of clinical medicine.
[2] E. Lespessailles,et al. Bariatric Surgery and Osteoporosis , 2021, Calcified Tissue International.
[3] Qiangqiang Li,et al. Role of sirtuins in bone biology: Potential implications for novel therapeutic strategies for osteoporosis , 2021, Aging cell.
[4] W. Högler,et al. Mechanisms of Bone Fragility: From Osteogenesis Imperfecta to Secondary Osteoporosis , 2021, International journal of molecular sciences.
[5] H. Takayanagi. RANKL as the master regulator of osteoclast differentiation , 2021, Journal of Bone and Mineral Metabolism.
[6] Zuolin Wang,et al. Trem2 mediated Syk-dependent ROS amplification is essential for osteoclastogenesis in periodontitis microenvironment , 2020, Redox biology.
[7] H. Neumann,et al. A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease‐associated variants on receptor signaling and activation by antibodies against the stalk region , 2020, Glia.
[8] X. Cui,et al. Mechanism of TREM2/DAP12 complex affecting β-amyloid plaque deposition in Alzheimer's disease modeled mice through mediating inflammatory response , 2020, Brain Research Bulletin.
[9] Haiyoung Jung,et al. Molecular Mechanisms and Emerging Therapeutics for Osteoporosis , 2020, International journal of molecular sciences.
[10] B. Grigolo,et al. Learning from Monocyte-Macrophage Fusion and Multinucleation: Potential Therapeutic Targets for Osteoporosis and Rheumatoid Arthritis , 2020, International journal of molecular sciences.
[11] I. Lambrinoudaki,et al. Estrogen and bones after menopause: a reappraisal of data and future perspectives , 2020, Hormones.
[12] Jung-Min Kim,et al. Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy , 2020, Molecular therapy. Methods & clinical development.
[13] A. Qian,et al. F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways , 2020, International journal of biological sciences.
[14] A. Rezapour,et al. Economic burden of osteoporosis in the world: A systematic review , 2020, Medical journal of the Islamic Republic of Iran.
[15] Jennifer J Kelly,et al. Combination therapies in the treatment of osteoporosis. , 2019, Current opinion in endocrinology, diabetes, and obesity.
[16] M. Kverka,et al. Update on Menopausal Hormone Therapy for Fracture Prevention , 2019, Current Osteoporosis Reports.
[17] Z. Ouyang,et al. Glycyrrhizic acid suppresses osteoclast differentiation and postmenopausal osteoporosis by modulating the NF-κB, ERK, and JNK signaling pathways. , 2019, European journal of pharmacology.
[18] A. Qian,et al. Microtubule actin crosslinking factor 1 (MACF1) knockdown inhibits RANKL-induced osteoclastogenesis via Akt/GSK3β/NFATc1 signalling pathway , 2019, Molecular and Cellular Endocrinology.
[19] Ajay Kumar,et al. Interplay of ERα binding and DNA methylation in the intron-2 determines the expression and estrogen regulation of cystatin A in breast cancer cells , 2019, Molecular and Cellular Endocrinology.
[20] Anna Teti,et al. Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions , 2019, Front. Immunol..
[21] F. Uhle,et al. From macrophage to osteoclast – How metabolism determines function and activity , 2018, Cytokine.
[22] S. Inoue,et al. The Sealing Zone in Osteoclasts: A Self-Organized Structure on the Bone , 2018, International journal of molecular sciences.
[23] Junjie Xing,et al. DOK3 Modulates Bone Remodeling by Negatively Regulating Osteoclastogenesis and Positively Regulating Osteoblastogenesis , 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[24] P. Katsimbri. The biology of normal bone remodelling , 2017, European journal of cancer care.
[25] Soo Young Lee,et al. Current Understanding of RANK Signaling in Osteoclast Differentiation and Maturation , 2017, Molecules and cells.
[26] Huaxi Xu,et al. TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway , 2017, Front. Aging Neurosci..
[27] Junfeng Cai,et al. Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling , 2016, Aging Clinical and Experimental Research.
[28] M. B. Humphrey,et al. A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts , 2016, Clinical Reviews in Allergy & Immunology.
[29] B. Komm,et al. The safety and tolerability profile of therapies for the prevention and treatment of osteoporosis in postmenopausal women , 2015, Expert review of clinical pharmacology.
[30] Ju-Young Kim,et al. Massive elimination of multinucleated osteoclasts by eupatilin is due to dual inhibition of transcription and cytoskeletal rearrangement , 2015, Bone reports.
[31] M. Kassem,et al. Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells. , 2015, Stem cell research.
[32] L. Yao,et al. DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis , 2015, Science Signaling.
[33] M. Mazzorana,et al. DAP12 Overexpression Induces Osteopenia and Impaired Early Hematopoiesis , 2013, PloS one.
[34] M. Jurkowska,et al. Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12. , 2013, Human immunology.
[35] J. Cauley,et al. Changes in bone resorption across the menopause transition: effects of reproductive hormones, body size, and ethnicity. , 2013, The Journal of clinical endocrinology and metabolism.
[36] R. Baron,et al. Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation. , 2013, The Journal of clinical investigation.
[37] D. Kelsell,et al. Mutations in CSTA, encoding Cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. , 2011, American journal of human genetics.
[38] H. Takayanagi,et al. Ca2+‐NFATc1 signaling is an essential axis of osteoclast differentiation , 2009, Immunological reviews.
[39] F. Ross. M‐CSF, c‐Fms, and Signaling in Osteoclasts and their Precursors , 2006, Annals of the New York Academy of Sciences.
[40] L. Lanier,et al. TREM2, a DAP12‐Associated Receptor, Regulates Osteoclast Differentiation and Function , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[41] A. Mócsai,et al. The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase , 2004 .
[42] C. Buonsanti,et al. Impaired Differentiation of Osteoclasts in TREM-2–deficient Individuals , 2003, The Journal of experimental medicine.
[43] L. Peltonen,et al. DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features , 2003, The Journal of experimental medicine.
[44] L. Peltonen,et al. Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype. , 2002, American journal of human genetics.
[45] G. V. D. Van der Weijden,et al. Cystatin A in gingival crevicular fluid of periodontal patients. , 1997, Journal of periodontal research.
[46] H. Bernstein,et al. Cystatin a-like immunoreactivity is widely distributed in human brain and accumulates in neuritic plaques of alzheimer disease subjects , 1994, Brain Research Bulletin.