Photoelectrochemical bioanalysis: the state of the art.

The evolution of photoelectrochemical (PEC) bioanalysis has resulted in substantial progress in its analytical performance and biodetection applications. The aim of this review is to provide a panoramic snapshot of the state of the art in this dynamically developing field, with special emphasis on PEC DNA analysis, immunoassay, enzymatic biosensing and cell-related detection. The future prospects in this area are also evaluated and discussed. This work will serve as a useful source to inform the interested audience of the latest developments and applications in the field of PEC bioanalysis.

[1]  Linlin Tang,et al.  Visible-light-activated photoelectrochemical biosensor for the study of acetylcholinesterase inhibition induced by endogenous neurotoxins. , 2013, Biosensors & bioelectronics.

[2]  Akimitsu Okamoto,et al.  DNA hole transport on an electrode: application to effective photoelectrochemical SNP typing. , 2006, Journal of the American Chemical Society.

[3]  Hongyan Wu,et al.  A photoelectrochemical sensor based on nickel hydroxyl-oxide modified n-silicon electrode for hydrogen peroxide detection in an alkaline solution. , 2013, Biosensors & bioelectronics.

[4]  Jingjing Xu,et al.  Photosynthetic reaction center functionalized nano-composite films: effective strategies for probing and exploiting the photo-induced electron transfer of photosensitive membrane protein. , 2007, Biosensors & bioelectronics.

[5]  Gui Yin,et al.  Phthalocyanine-sensitized graphene-CdS nanocomposites: an enhanced photoelectrochemical immunosensing platform. , 2013, Chemistry.

[6]  Hongwei Song,et al.  Zinc oxide inverse opal electrodes modified by glucose oxidase for electrochemical and photoelectrochemical biosensor. , 2014, Biosensors & bioelectronics.

[7]  Xiangfeng Duan,et al.  Progress, challenge and perspective of heterogeneous photocatalysts. , 2013, Chemical Society reviews.

[8]  Bin Du,et al.  A novel multi-amplification photoelectrochemical immunoassay based on copper(II) enhanced polythiophene sensitized graphitic carbon nitride nanosheet. , 2014, Biosensors & bioelectronics.

[9]  Bing Sun,et al.  Ultrasensitive photoelectrochemical immunoassay of indole-3-acetic acid based on the MPA modified CdS/RGO nanocomposites decorated ITO electrode. , 2014, Biosensors & bioelectronics.

[10]  Serge Cosnier,et al.  Electrogeneration of a biotinylated poly(pyrrole-ruthenium(II)) film for the construction of photoelectrochemical immunosensor. , 2004, Chemical communications.

[11]  Xiaoling Yang,et al.  Photoelectrochemical glucose biosensor incorporating CdS nanoparticles , 2009 .

[12]  Anthony P F Turner,et al.  Biosensors: sense and sensibility. , 2013, Chemical Society reviews.

[13]  Izumi Kubo,et al.  Novel sensors for potassium, calcium and magnesium ions based on a silicon transducer as a light-addressable potentiometric sensor , 1999 .

[14]  Wolfgang J Parak,et al.  Quantum dots on gold: electrodes for photoswitchable cytochrome C electrochemistry. , 2006, Small.

[15]  Jun-Jie Zhu,et al.  Dual-signal amplification strategy for ultrasensitive photoelectrochemical immunosensing of α-fetoprotein. , 2012, Analytical chemistry.

[16]  Peng Wang,et al.  Photoelectrochemistry of free-base-porphyrin-functionalized zinc oxide nanoparticles and their applications in biosensing. , 2011, Chemistry.

[17]  J J Valdes,et al.  Detection of Yersinia pestis using branched DNA. , 1999, Molecular and cellular probes.

[18]  Teruaki Katsube,et al.  Novel type cholinesterase sensor based on SPV measurement technique , 2000 .

[19]  Fei Wang,et al.  Study on acetylcholinesterase inhibition induced by endogenous neurotoxin with an enzyme-semiconductor photoelectrochemical system. , 2009, Chemical communications.

[20]  J. W. Parce,et al.  The light-addressable potentiometric sensor: principles and biological applications. , 1994, Annual review of biophysics and biomolecular structure.

[21]  Wei-Wei Zhao,et al.  The coupling of localized surface plasmon resonance-based photoelectrochemistry and nanoparticle size effect: towards novel plasmonic photoelectrochemical biosensing. , 2012, Chemical communications.

[22]  G. Luo,et al.  Photoelectrochemistry as a novel strategy for DNA hybridization detection. , 2000, The Analyst.

[23]  Joseph Wang Electrochemical glucose biosensors. , 2008, Chemical reviews.

[24]  Qingyun Cai,et al.  Highly sensitive and selective photoelectrochemical biosensor platform for polybrominated diphenyl ether detection using the quantum dots sensitized three-dimensional, macroporous ZnO nanosheet photoelectrode. , 2014, Biosensors & bioelectronics.

[25]  Wei-Wei Zhao,et al.  Acetylcholine esterase antibodies on BiOI nanoflakes/TiO2 nanoparticles electrode: a case of application for general photoelectrochemical enzymatic analysis. , 2013, Analytical chemistry.

[26]  Thomas E Mallouk,et al.  Design and development of photoanodes for water-splitting dye-sensitized photoelectrochemical cells. , 2013, Chemical Society reviews.

[27]  Frank E. Osterloh,et al.  Inorganic nanostructures for photoelectrochemical and photocatalytic water splitting. , 2013, Chemical Society reviews.

[28]  Michael Holzinger,et al.  Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: application to the determination of thrombin and anti-cholera toxin antibody. , 2013, Biosensors & bioelectronics.

[29]  M. Grätzel Photoelectrochemical cells : Materials for clean energy , 2001 .

[30]  Xizeng Feng,et al.  Label-free biosensor: a novel phage-modified Light Addressable Potentiometric Sensor system for cancer cell monitoring. , 2007, Biosensors & bioelectronics.

[31]  Y. Ci,et al.  Photoelectric behavior of mammalian cells and its bioanalytical applications , 1998 .

[32]  Wei-Wei Zhao,et al.  Highly sensitive photoelectrochemical immunoassay with enhanced amplification using horseradish peroxidase induced biocatalytic precipitation on a CdS quantum dots multilayer electrode. , 2012, Analytical chemistry.

[33]  J. W. Parce,et al.  Detection of cell-affecting agents with a silicon biosensor. , 1989, Science.

[34]  Itamar Willner,et al.  Self-assembly of semiconductor quantum-dots on electrodes for photoelectrochemical biosensing , 2007, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[35]  K Dill,et al.  Detection of plasmids using DNA and RNA probes and the light-addressable potentiometric sensor. , 1997, Journal of biochemical and biophysical methods.

[36]  Atsushi Ikeda,et al.  Photoelectrochemical sensor with porphyrin-deposited electrodes for determination of nucleotides in water. , 2009, Organic letters.

[37]  Dong Han,et al.  Zinc oxide nanoparticles/glucose oxidase photoelectrochemical system for the fabrication of biosensor. , 2009, Journal of colloid and interface science.

[38]  Guang-Li Wang,et al.  Dopamine sensitized nanoporous TiO2 film on electrodes: photoelectrochemical sensing of NADH under visible irradiation. , 2009, Biosensors & bioelectronics.

[39]  Wei-Wei Zhao,et al.  In situ modification of a semiconductor surface by an enzymatic process: a general strategy for photoelectrochemical bioanalysis. , 2013, Analytical chemistry.

[40]  Jacqueline K Barton,et al.  DNA charge transport: conformationally gated hopping through stacked domains. , 2004, Journal of the American Chemical Society.

[41]  Wei-Wei Zhao,et al.  Cell surface carbohydrates evaluation via a photoelectrochemical approach. , 2012, Chemical communications.

[42]  Itamar Willner,et al.  Electrochemical control of the photocurrent direction in intercalated DNA/CdS nanoparticle systems. , 2005, Angewandte Chemie.

[43]  Jing Wang,et al.  Energy transfer between CdS quantum dots and Au nanoparticles in photoelectrochemical detection. , 2011, Chemical communications.

[44]  Qingyun Cai,et al.  Label-free photoelectrochemical immunosensor based on CdTe/CdS co-sensitized TiO2 nanotube array structure for octachlorostyrene detection. , 2013, Biosensors & bioelectronics.

[45]  Xiaoru Zhang,et al.  A new strategy for photoelectrochemical DNA biosensor using chemiluminescence reaction as light source. , 2011, Biosensors & bioelectronics.

[46]  Yongping Luo,et al.  Plasmon-induced enhancement in analytical performance based on gold nanoparticles deposited on TiO2 film. , 2009, Analytical chemistry.

[47]  Jing-Juan Xu,et al.  Label-free photoelectrochemical immunoassay for alpha-fetoprotein detection based on TiO(2)/CdS hybrid. , 2009, Biosensors & bioelectronics.

[48]  W. Vastarella,et al.  Enzyme/semiconductor nanoclusters combined systems for novel amperometric biosensors. , 2005, Talanta.

[49]  Xiaoru Zhang,et al.  A new photoelectrochemical biosensors based on DNA conformational changes and isothermal circular strand-displacement polymerization reaction. , 2013, Biosensors & bioelectronics.

[50]  H Merrick,et al.  A silicon sensor-based filtration immunoassay using biotin-mediated capture. , 1990, Journal of immunological methods.

[51]  Chi Zhang,et al.  A new approach to light up the application of semiconductor nanomaterials for photoelectrochemical biosensors: using self-operating photocathode as a highly selective enzyme sensor. , 2014, Biosensors & bioelectronics.

[52]  Bing Sun,et al.  A new strategy for methylated DNA detection based on photoelectrochemical immunosensor using Bi2S3 nanorods, methyl bonding domain protein and anti-his tag antibody. , 2014, Biosensors & bioelectronics.

[53]  Harry O. Finklea,et al.  Photoelectrochemistry: Introductory Concepts. , 1983 .

[54]  Xiaoli Zhu,et al.  Hemoglobin-based hydrogen peroxide biosensor tuned by the photovoltaic effect of nano titanium dioxide. , 2005, Analytical chemistry.

[55]  Itamar Willner,et al.  Plugging into enzymes with light: photonic "wiring" of enzymes with electrodes for photobiofuel cells. , 2010, Small.

[56]  Ming Xu,et al.  Photoelectrochemical detection of glutathione by IrO2-hemin-TiO2 nanowire arrays. , 2013, Nano letters.

[57]  Yan Li,et al.  Cell-based biosensors based on light-addressable potentiometric sensors for single cell monitoring. , 2005, Biosensors & bioelectronics.

[58]  Jinghong Li,et al.  Biofunctional titania nanotubes for visible-light-activated photoelectrochemical biosensing. , 2010, Analytical chemistry.

[59]  Itamar Willner,et al.  Electrochemical, photoelectrochemical, and piezoelectric analysis of tyrosinase activity by functionalized nanoparticles. , 2008, Analytical chemistry.

[60]  L. Peter,et al.  Dynamic aspects of semiconductor photoelectrochemistry , 1990 .

[61]  Xiaoru Zhang,et al.  Aptamer based photoelectrochemical cytosensor with layer-by-layer assembly of CdSe semiconductor nanoparticles as photoelectrochemically active species. , 2011, Biosensors & bioelectronics.

[62]  Shouzhuo Yao,et al.  Photoelectrochemical detection of pentachlorophenol with a multiple hybrid CdSe(x)Te(1-x)/TiO2 nanotube structure-based label-free immunosensor. , 2010, Analytical chemistry.

[63]  Guang-Li Wang,et al.  Selective detection of trace amount of Cu2+ using semiconductor nanoparticles in photoelectrochemical analysis. , 2010, Nanoscale.

[64]  Liang-Hong Guo,et al.  Label-free and selective photoelectrochemical detection of chemical DNA methylation damage using DNA repair enzymes. , 2013, Analytical chemistry.

[65]  Yang Li,et al.  Ultrasensitive determination of cysteine based on the photocurrent of nafion-functionalized CdS-MV quantum dots on an ITO electrode. , 2011, Small.

[66]  M Zanella,et al.  Photoelectrochemical signal chain based on quantum dots on gold--sensitive to superoxide radicals in solution. , 2008, Biosensors & bioelectronics.

[67]  V T Kung,et al.  Detection of antibody to the PreS2 sequence of the hepatitis B virus envelope protein using an immuno-ligand assay with a silicon sensor detection system. , 1991, Journal of immunological methods.

[68]  Kim R. Rogers,et al.  Rapid detection of anticholinesterase insecticides by a reusable light addressable potentiometric biosensor , 1993 .

[69]  Wei-Wei Zhao,et al.  Ultrasensitive photoelectrochemical biosensing based on biocatalytic deposition , 2011 .

[70]  Akimitsu Okamoto,et al.  Photostimulated hole transport through a DNA duplex immobilized on a gold electrode. , 2004, Journal of the American Chemical Society.

[71]  E. Sheldon,et al.  Picogram quantitation of total DNA using DNA-binding proteins in a silicon sensor-based system. , 1990, Analytical biochemistry.

[72]  Xie Quan,et al.  Photoelectrochemical immunoassay for microcystin-LR based on a fluorine-doped tin oxide glass electrode modified with a CdS-graphene composite , 2012, Microchimica Acta.

[73]  I. Willner,et al.  Semiconductor quantum dots for bioanalysis. , 2008, Angewandte Chemie.

[74]  Qing Huang,et al.  Improved sensitivity of polychlorinated-biphenyl-orientated porous-ZnO surface photovoltage sensors from chemisorption-formed ZnO-CuPc composites , 2014, Scientific Reports.

[75]  Teruaki Katsube,et al.  Integrated biosensor employing a surface photovoltage technique , 1994 .

[76]  Jing-Juan Xu,et al.  A Label-Free Photoelectrochemical Immunosensor Based on Water-Soluble CdS Quantum Dots , 2009 .

[77]  Chun-hui Huang,et al.  Photoelectric behavior of supercoiled DNA and its applications in molecular biology , 1998 .

[78]  Michael J. Schöning,et al.  Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS? , 2001 .

[79]  Qin Xu,et al.  A novel photoelectrochemical sensor for the organophosphorus pesticide dichlofenthion based on nanometer-sized titania coupled with a screen-printed electrode. , 2011, Analytical chemistry.

[80]  Minmin Liang,et al.  Photoelectrochemical DNA sensor for the rapid detection of DNA damage induced by styrene oxide and the Fenton reaction. , 2007, Environmental science & technology.

[81]  M. Mascini,et al.  Electrochemical nucleic acid-based biosensors: Concepts, terms, and methodology (IUPAC Technical Report) , 2010 .

[82]  Qingming Shen,et al.  ZnO/CdS Hierarchical Nanospheres for Photoelectrochemical Sensing of Cu2+ , 2011 .

[83]  Jing Wang,et al.  Immunogold labeling-induced synergy effect for amplified photoelectrochemical immunoassay of prostate-specific antigen. , 2012, Chemical communications.

[84]  Sanghamitra Chatterjee,et al.  Nanomaterials based electrochemical sensors for biomedical applications. , 2013, Chemical Society reviews.

[85]  Huangxian Ju,et al.  Chemiluminescence excited photoelectrochemistry using graphene-quantum dots nanocomposite for biosensing. , 2012, Chemical communications.

[86]  Chunhai Fan,et al.  Functional nanoprobes for ultrasensitive detection of biomolecules: an update. , 2014, Chemical Society reviews.

[87]  G. S. Wilson,et al.  Electrochemical Biosensors: Recommended Definitions and Classification , 1999, Biosensors & bioelectronics.

[88]  Stephen G. Weber,et al.  Photoelectrochemical sensor for catalase activity based on the in situ generation and detection of substrate , 1993 .

[89]  Hiroshi Iwasaki,et al.  Portable light-addressable potentiometric sensor (LAPS) for multisensor applications , 2003 .

[90]  Xiaoru Zhang,et al.  Low-toxic Ag2S quantum dots for photoelectrochemical detection glucose and cancer cells. , 2014, Biosensors & bioelectronics.

[91]  Alexander J. Cowan,et al.  Long-lived charge separated states in nanostructured semiconductor photoelectrodes for the production of solar fuels. , 2013, Chemical Society reviews.

[92]  Lan-sun Zheng,et al.  Semiconductor@metal-organic framework core-shell heterostructures: a case of ZnO@ZIF-8 nanorods with selective photoelectrochemical response. , 2013, Journal of the American Chemical Society.

[93]  Itamar Willner,et al.  Controlling the direction of photocurrents by means of CdS nanoparticles and cytochrome c-mediated biocatalytic cascades. , 2006, Chemical communications.

[94]  Serge Cosnier,et al.  Photoelectrochemical immunosensor for label-free detection and quantification of anti-cholera toxin antibody. , 2006, Journal of the American Chemical Society.

[95]  Minmin Liang,et al.  Photoelectrochemical detection of oxidative DNA damage induced by Fenton reaction with low concentration and DNA-associated Fe2+. , 2008, The journal of physical chemistry. B.

[96]  Wei-Wei Zhao,et al.  In situ enzymatic ascorbic acid production as electron donor for CdS quantum dots equipped TiO2 nanotubes: a general and efficient approach for new photoelectrochemical immunoassay. , 2012, Analytical chemistry.

[97]  Shuxian Dong,et al.  A TiO2-Au-polymer hybrid system for the photoelectrochemical immunoassay of SirT1. , 2014, Journal of materials chemistry. B.

[98]  Xiaoru Zhang,et al.  Photoelectrochemical biosensor for detection of adenosine triphosphate in the extracts of cancer cells. , 2010, Chemical communications.

[99]  K. Dill,et al.  Determination of dissociation constant and concentration of an anti-DNA antibody by using the light-addressable potentiometric sensor. , 1996, Journal of biochemical and biophysical methods.

[100]  Meng Li,et al.  A visible light photoelectrochemical sensor for tumor marker detection using tin dioxide quantum dot-graphene as labels. , 2013, The Analyst.

[101]  Wei Zhang,et al.  A novel design of multifunctional integrated cell-based biosensors for simultaneously detecting cell acidification and extracellular potential. , 2009, Biosensors & bioelectronics.

[102]  Bing Sun,et al.  DNA methyltransferase activity assay based on visible light-activated photoelectrochemical biosensor. , 2014, Biosensors & bioelectronics.

[103]  Zhiqiang Gao,et al.  An ultrasensitive photoelectrochemical nucleic acid biosensor , 2005, Nucleic acids research.

[104]  Xiaoru Zhang,et al.  A new signal-on photoelectrochemical biosensor based on a graphene/quantum-dot nanocomposite amplified by the dual-quenched effect of bipyridinium relay and AuNPs. , 2012, Chemistry.

[105]  Xiaoli Zhu,et al.  Electrochemical study of the effect of nano-zinc oxide on microperoxidase and its application to more sensitive hydrogen peroxide biosensor preparation. , 2007, Biosensors & bioelectronics.

[106]  E Artacho,et al.  Absence of dc-conductivity in lambda-DNA. , 2000, Physical review letters.

[107]  Shenguang Ge,et al.  A novel microfluidic origami photoelectrochemical sensor based on CdTe quantum dots modified molecularly imprinted polymer and its highly selective detection of S-fenvalerate , 2013 .

[108]  Jing Wang,et al.  Exciton-plasmon interactions between CdS quantum dots and Ag nanoparticles in photoelectrochemical system and its biosensing application. , 2012, Analytical chemistry.

[109]  Qingyun Cai,et al.  A photoelectrochemical immunosensor for tris(2,3-dibromopropyl) isocyanurate detection with a multiple hybrid CdTe/Au-TiO2 nanotube arrays. , 2013, The Analyst.

[110]  Huangxian Ju,et al.  Low-potential photoelectrochemical biosensing using porphyrin-functionalized TiO₂ nanoparticles. , 2010, Analytical chemistry.

[111]  Wei-Wei Zhao,et al.  Photoelectrochemical DNA biosensors. , 2014, Chemical reviews.

[112]  Zhao Yue,et al.  Quantum-dot-based photoelectrochemical sensors for chemical and biological detection. , 2013, ACS applied materials & interfaces.

[113]  Itamar Willner,et al.  Photoelectrochemical Biosensors Without External Irradiation: Probing Enzyme Activities and DNA Sensing Using Hemin/G-Quadruplex-Stimulated Chemiluminescence Resonance Energy Transfer (CRET) Generation of Photocurrents , 2012 .

[114]  Kewei Wang,et al.  Highly sensitive visible light activated photoelectrochemical biosensing of organophosphate pesticide using biofunctional crossed bismuth oxyiodide flake arrays. , 2012, Biosensors & bioelectronics.

[115]  Xiaoru Zhang,et al.  Photoelectrochemically active species and photoelectrochemical biosensors , 2013 .

[116]  Huiqiong Zhou,et al.  Enhanced Photoelectrochemical Detection of Bioaffinity Reactions by Vertically Oriented Au Nanobranches Complexed with a Biotinylated Polythiophene Derivative , 2009, Sensors.

[117]  Hui Ma,et al.  A Photoelectric Method for Analyzing NO‐Induced Apoptosis in Cultured Neuronal Cells , 2000 .

[118]  Junwei Di,et al.  ZnS nanoparticles electrodeposited onto ITO electrode as a platform for fabrication of enzyme-based biosensors of glucose. , 2013, Materials science & engineering. C, Materials for biological applications.

[119]  Meicheng Yang,et al.  A photoelectrochemical immunosensor based on Au-doped TiO2 nanotube arrays for the detection of α-synuclein. , 2010, Chemistry.

[120]  Qingming Shen,et al.  Graphene-CdS nanocomposites: facile one-step synthesis and enhanced photoelectrochemical cytosensing. , 2012, Chemistry.

[121]  Yongping Luo,et al.  Switching the direction of plasmon-induced photocurrents by cytochrome c at Au-TiO(2) nanocomposites. , 2009, Chemical communications.

[122]  Liang-Hong Guo,et al.  Detection and mechanistic investigation of halogenated benzoquinone induced DNA damage by photoelectrochemical DNA sensor , 2010, Analytical and bioanalytical chemistry.

[123]  Xiaoru Zhang,et al.  A new photoelectrochemical aptasensor for the detection of thrombin based on functionalized graphene and CdSe nanoparticles multilayers. , 2011, Chemical communications.

[124]  Bing Sun,et al.  Photoelectrochemical biosensing platform for microRNA detection based on in situ producing electron donor from apoferritin-encapsulated ascorbic acid. , 2014, Biosensors & bioelectronics.

[125]  Hong-Yuan Chen,et al.  Progress in the studies of photoelectrochemical sensors , 2009 .

[126]  T. G. Drummond,et al.  Electrochemical DNA sensors , 2003, Nature Biotechnology.

[127]  Meng Xiong,et al.  Photoelectrochemical bioanalysis: A mini review , 2014 .

[128]  Dong Zheng,et al.  Quantitative photoelectrochemical detection of biological affinity reaction: biotin-avidin interaction. , 2004, Analytical chemistry.

[129]  Gianaurelio Cuniberti,et al.  Charge transport in DNA-based devices , 2004, cond-mat/0403640.

[130]  Guang-Li Wang,et al.  A photoelectrochemical sensor based on CdS-polyamidoamine nano-composite film for cell capture and detection. , 2010, Biosensors & bioelectronics.

[131]  Tadao Takada,et al.  Relationship between charge transfer and charge recombination determines photocurrent efficiency through DNA films. , 2007, Angewandte Chemie.

[132]  Marc M Greenberg,et al.  Quantification of 8-oxodGuo lesions in double-stranded DNA using a photoelectrochemical DNA sensor. , 2012, Analytical chemistry.

[133]  Xiaoling Yang,et al.  Self-assembled CNTs/CdS/dehydrogenase hybrid-based amperometric biosensor triggered by photovoltaic effect. , 2008, Biosensors & bioelectronics.

[134]  Huangxian Ju,et al.  Visible light induced photoelectrochemical biosensing based on oxygen-sensitive quantum dots. , 2012, Analytica chimica acta.

[135]  I. Willner,et al.  Nucleic acid/quantum dots (QDs) hybrid systems for optical and photoelectrochemical sensing. , 2013, ACS applied materials & interfaces.

[136]  Jaebeom Lee,et al.  Exciton-plasmon interactions in molecular spring assemblies of nanowires and wavelength-based protein detection. , 2007, Nature materials.

[137]  J. W. Parce,et al.  Light-addressable potentiometric sensor for biochemical systems. , 1988, Science.

[138]  Huimin Zhao,et al.  Fabrication of graphene quantum dots/silicon nanowires nanohybrids for photoelectrochemical detection of microcystin-LR , 2014 .

[139]  Fei Xiao,et al.  Photoelectrochemical Immunosensor Array Based on Thioglycolic Acid Capped CdS Quantum Dots for Multiplexed Detection of Veterinary Drug Residues , 2012 .

[140]  Zhihui Dai,et al.  Using graphene-based plasmonic nanocomposites to quench energy from quantum dots for signal-on photoelectrochemical aptasensing. , 2013, Analytical chemistry.

[141]  Roberto Pilloton,et al.  A biosensor for the detection of triazine and phenylurea herbicides designed using Photosystem II coupled to a screen-printed electrode. , 2002, Biotechnology and bioengineering.

[142]  Kazuhito Tanabe,et al.  Photocurrent response after enzymatic treatment of DNA duplexes immobilized on gold electrodes: electrochemical discrimination of 5-methylcytosine modification in DNA. , 2008, Organic & biomolecular chemistry.

[143]  Xiaoling Yang,et al.  Immobilization of horseradish peroxidase in three-dimensional macroporous TiO2 matrices for biosensor applications , 2009 .

[144]  Lo Gorton,et al.  Photoelectrocatalytic oxidation of NADH with electropolymerized Toluidine Blue O , 2007 .

[145]  Antonia Mallardi,et al.  Development of a novel enzyme/semiconductor nanoparticles system for biosensor application , 2002 .

[146]  Jinou Zheng,et al.  Ultrasensitive all-carbon photoelectrochemical bioprobes for zeptomole immunosensing of tumor markers by an inexpensive visible laser light. , 2013, Analytical chemistry.

[147]  Wei-Wei Zhao,et al.  Ultrasensitive photoelectrochemical sensing of Pb2+ based on allosteric transition of G-Quadruplex DNAzyme , 2013 .

[148]  C A Grimes,et al.  A photoelectrochemical immunosensor for benzo[a]pyrene detection amplified by bifunctional gold nanoparticles. , 2011, Chemical communications.

[149]  Itamar Willner,et al.  Electrochemical, photoelectrochemical, and surface plasmon resonance detection of cocaine using supramolecular aptamer complexes and metallic or semiconductor nanoparticles. , 2009, Analytical chemistry.

[150]  I. Karube,et al.  BIOSENSORS BASED ON LIGHT-ADDRESSABLE POTENTIOMETRIC SENSORS FOR UREA, PENICILLIN AND GLUCOSE , 1998 .

[151]  Yoko Yamada,et al.  Photoelectrochemical deoxyribonucleic acid sensing on a nanostructured TiO2 electrode , 2005 .

[152]  Deniz Baş,et al.  Quantitative Photoelectrochemical Detection of Biotin Conjugated CdSe/ZnS Quantum Dots on the Avidin Immobilized ITO Electrodes , 2009 .

[153]  Lei Ge,et al.  A paper-based photoelectrochemical immunoassay for low-cost and multiplexed point-of-care testing. , 2013, Chemical communications.

[154]  Jian-Rong Zhang,et al.  A new signal amplification strategy of photoelectrochemical immunoassay for highly sensitive interleukin-6 detection based on TiO2/CdS/CdSe dual co-sensitized structure. , 2014, Biosensors & bioelectronics.

[155]  Shengchao Zhu,et al.  Photoelectrochemical sensor for the rapid detection of in situ DNA damage induced by enzyme-catalyzed fenton reaction. , 2008, Environmental science & technology.

[156]  Bing Sun,et al.  Signal-on photoelectrochemical biosensor for microRNA detection based on Bi2S3 nanorods and enzymatic amplification. , 2014, Biosensors & bioelectronics.

[157]  Jing-Juan Xu,et al.  Distance-dependent quenching and enhancing of electrochemiluminescence from a CdS:Mn nanocrystal film by Au nanoparticles for highly sensitive detection of DNA. , 2009, Chemical communications.

[158]  Itamar Willner,et al.  Photoelectrochemistry with Controlled DNA-Cross-Linked CdS Nanoparticle Arrays This research is supported by The U.S.-Israel Binational Science Foundation. The Max Planck Research Award for International Cooperation (I.W.) is gratefully acknowledged. , 2001, Angewandte Chemie.

[159]  J. Hall,et al.  Rapid detection and identification of biological and chemical agents by immunoassay, gene probe assay and enzyme inhibition using a silicon-based biosensor. , 2000, Biosensors & bioelectronics.

[160]  Jinghong Li,et al.  Enhanced photoelectrochemical method for linear DNA hybridization detection using Au-nanopaticle labeled DNA as probe onto titanium dioxide electrode. , 2008, Biosensors & bioelectronics.

[161]  Chao Li,et al.  Selective photoelectrochemical detection of DNA with high-affinity metallointercalator and tin oxide nanoparticle electrode. , 2006, Analytical chemistry.

[162]  R. Frese,et al.  Evaluation of a biohybrid photoelectrochemical cell employing the purple bacterial reaction centre as a biosensor for herbicides , 2014, Biosensors & bioelectronics.

[163]  Guoqiang Sun,et al.  Paper-based photoelectrochemical immunosensing based on CdS QD sensitized multidimensional porous ZnO spheres promoted by carbon nanotubes. , 2013, Chemical communications.

[164]  Zhiyong Tang,et al.  Photoelectrochemical sensing of glucose based on quantum dot and enzyme nanocomposites , 2011 .

[165]  Kazuhito Tanabe,et al.  Electrochemical evaluation of alternating duplex-triplex conversion effect on the anthraquinone-photoinjected hole transport through DNA duplex immobilized on a gold electrode. , 2006, Journal of the American Chemical Society.

[166]  Shuyan Niu,et al.  Ultrasensitive photoelectrochemical immunoassay of antibody against tumor-associated carbohydrate antigen amplified by functionalized graphene derivates and enzymatic biocatalytic precipitation. , 2014, Biosensors & bioelectronics.

[167]  Guohua Zhao,et al.  A Visible‐Light Driven Photoelectrochemical Aptasensor for Endocrine Disrupting Chemicals Bisphenol A with High Sensitivity and Specificity , 2013 .

[168]  Itamar Willner,et al.  Acetylcholine esterase-labeled CdS nanoparticles on electrodes: photoelectrochemical sensing of the enzyme inhibitors. , 2003, Journal of the American Chemical Society.

[169]  Shusheng Zhang,et al.  A new strategy of photoelectrochemical analysis without an external light source based on isoluminol chemiluminescence probe. , 2010, Chemical communications.

[170]  Yu Qin,et al.  Functional nanoprobes for ultrasensitive detection of biomolecules. , 2010, Chemical Society reviews.

[171]  Zhihui Dai,et al.  Quantum dots sensitized titanium dioxide decorated reduced graphene oxide for visible light excited photoelectrochemical biosensing at a low potential. , 2014, Biosensors & bioelectronics.

[172]  Huangxian Ju,et al.  Signal amplification using functional nanomaterials for biosensing. , 2012, Chemical Society reviews.

[173]  Yan Zhang,et al.  TiO2–graphene complex nanopaper for paper-based label-free photoelectrochemical immunoassay , 2013 .

[174]  F Lisdat,et al.  Light-controlled bioelectrochemical sensor based on CdSe/ZnS quantum dots. , 2011, Analytical chemistry.

[175]  Jinghong Li,et al.  Label-free photoelectrochemical strategy for hairpin DNA hybridization detection on titanium dioxide electrode , 2006 .