Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

[1]  Mariano J. Alvarez,et al.  Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling , 2011, Development.

[2]  M. Hendrix,et al.  Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells , 2011, The Prostate.

[3]  Jorge S. Reis-Filho,et al.  Microarray-Based Class Discovery for Molecular Classification of Breast Cancer: Analysis of Interobserver Agreement , 2011, Journal of the National Cancer Institute.

[4]  M. Hendrix,et al.  Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype. , 2010, Cancer research.

[5]  V. Band,et al.  Histological, molecular and functional subtypes of breast cancers , 2010, Cancer biology & therapy.

[6]  A. Thompson,et al.  Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS) , 2010, Breast Cancer Research.

[7]  P. Talbot,et al.  Comparison of the toxicity of smoke from conventional and harm reduction cigarettes using human embryonic stem cells. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.

[8]  E. Perez,et al.  Treatment options for patients with triple-negative breast cancer , 2010, Journal of hematology & oncology.

[9]  O. Ashur-Fabian,et al.  Thyroid hormones and cancer: clinical studies of hypothyroidism in oncology. , 2010, Current opinion in endocrinology, diabetes, and obesity.

[10]  D. Fullen,et al.  Expression of the embryonic morphogen Nodal in cutaneous melanocytic lesions , 2010, Modern Pathology.

[11]  B. Vonderhaar,et al.  CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer. , 2010, Cancer research.

[12]  Y-C Lee,et al.  Nodal promotes growth and invasion in human gliomas , 2010, Oncogene.

[13]  M. Gönen,et al.  Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. , 2010, The Journal of clinical investigation.

[14]  M. Lackmann,et al.  Expression of nodal signalling components in cycling human endometrium and in endometrial cancer , 2009, Reproductive biology and endocrinology : RB&E.

[15]  M. Wicha Targeting breast cancer stem cells. , 2009, Breast.

[16]  M. Hendrix,et al.  Development and cancer: at the crossroads of Nodal and Notch signaling. , 2009, Cancer research.

[17]  D. Constam Running the gauntlet: an overview of the modalities of travel employed by the putative morphogen Nodal. , 2009, Current opinion in genetics & development.

[18]  M. Hendrix,et al.  Potential for Cripto-1 in defining stem cell-like characteristics in human malignant melanoma , 2008, Cell cycle.

[19]  Ian O Ellis,et al.  Prognostic significance of Nottingham histologic grade in invasive breast carcinoma. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[20]  E. D. de Vries,et al.  Prognostic versus predictive value of biomarkers in oncology. , 2008, European journal of cancer.

[21]  M. Hendrix,et al.  Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells , 2008, Proceedings of the National Academy of Sciences.

[22]  M. J. van de Vijver,et al.  Immunohistochemical categorisation of ductal carcinoma in situ of the breast , 2007, British Journal of Cancer.

[23]  R. Bast,et al.  American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer. , 2007, Journal of oncology practice.

[24]  M. Shen Nodal signaling: developmental roles and regulation , 2007, Development.

[25]  D. Constam,et al.  The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. , 2006, Developmental cell.

[26]  G. D'aiuto,et al.  Identification of Cripto-1 as a Novel Serologic Marker for Breast and Colon Cancer , 2006, Clinical Cancer Research.

[27]  M. Hendrix,et al.  Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness , 2006, Nature Medicine.

[28]  David Salomon,et al.  Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis , 2005, Oncogene.

[29]  G. Chetrite,et al.  Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer , 2005, The Journal of Steroid Biochemistry and Molecular Biology.

[30]  R. Pedersen,et al.  Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. , 2004, Developmental biology.

[31]  G. Baldwin,et al.  Gastrins, cholecystokinins and gastrointestinal cancer. , 2004, Biochimica et biophysica acta.

[32]  A. Schier Nodal signaling in vertebrate development. , 2003, Annual review of cell and developmental biology.

[33]  B. Moon,et al.  Secretory carcinoma of the breast , 2003, Journal of clinical ultrasound : JCU.

[34]  S. Morrison,et al.  Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[35]  R. Kaaks,et al.  Obesity , Endogenous Hormones , and Endometrial Cancer Risk : A Synthetic Review 1 , 2002 .

[36]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[37]  Shousha,et al.  Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins , 1999, Histopathology.

[38]  G. Chetrite,et al.  Progestins and breast cancer 1 1 Proceedings of the 13th International Symposium of the Journal of Steroid Biochemistry & Molecular Biology “Recent Advances in Steroid Biochemistry & Molecular Biology” Monaco, 25–28 May 1997. , 1998, The Journal of Steroid Biochemistry and Molecular Biology.

[39]  Raj Kumar,et al.  Steroid hormone receptors in cancer development: a target for cancer therapeutics. , 2011, Cancer letters.

[40]  M. Hendrix,et al.  Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention. , 2009, Expert review of dermatology.

[41]  M. Hendrix,et al.  Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression. , 2008, Breast disease.