Systemic interleukin 10 administration inhibits brain tumor necrosis factor production in mice.

[1]  G. Fantuzzi,et al.  Role of the hypothalamus-pituitary-adrenal axis in the regulation of TNF production in mice. Effect of stress and inhibition of endogenous glucocorticoids. , 1995, Journal of immunology.

[2]  L. Shapiro,et al.  A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. , 1995, Journal of immunology.

[3]  P. Ghezzi,et al.  lnterleukin-10 Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor and Interleukin-1β Production in the Brain without Affecting the Activation of the Hypothalamus-Pituitary-Adrenal Axis , 1995 .

[4]  G. Fantuzzi,et al.  Independent down-regulation of central and peripheral tumor necrosis factor production as a result of lipopolysaccharide tolerance in mice , 1995, Infection and immunity.

[5]  T. Marunouchi,et al.  Production of interleukin-10 by mouse glial cells in culture. , 1994, Biochemical and biophysical research communications.

[6]  B. Fleischer,et al.  Interleukin‐10 prevents experimental allergic encephalomyelitis in rats , 1994, European journal of immunology.

[7]  W. Banks,et al.  Murine tumor necrosis factor alpha is transported from blood to brain in the mouse , 1993, Journal of Neuroimmunology.

[8]  W. Fiers,et al.  Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia , 1993, The Journal of experimental medicine.

[9]  K. Mohler,et al.  Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. , 1992, Journal of immunology.

[10]  A. Mantovani,et al.  Differential sensitivity of in vivo TNF and IL-6 production to modulation by anti-inflammatory drugs in mice. , 1992, International journal of immunopharmacology.

[11]  C G Figdor,et al.  Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes , 1991, The Journal of experimental medicine.

[12]  J. M. Lipton,et al.  Central administration of the peptide α-MSH inhibits inflammation in the skin , 1991, Peptides.

[13]  R. Clark,et al.  An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis , 1990, The Journal of experimental medicine.

[14]  C. Blatteis.  Neuromodulative actions of cytokines. , 1990, The Yale journal of biology and medicine.

[15]  A. Cerami,et al.  The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis , 1990, The Journal of experimental medicine.

[16]  L. F. Fajardo,et al.  Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. , 1987, Science.

[17]  J. Stitt,et al.  Differences in endogenous pyrogen fevers induced by iv and icv routes in rabbits. , 1985, Journal of applied physiology.

[18]  D. Goeddel,et al.  Human tumor necrosis factor. Production, purification, and characterization. , 1985, The Journal of biological chemistry.

[19]  L. Jacobs,et al.  Intrathecal interferon reduces exacerbations of multiple sclerosis. , 1981, Science.

[20]  T. Haley,et al.  Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. , 1957, British journal of pharmacology and chemotherapy.

[21]  P. Ghezzi,et al.  Proinflammatory cytokines as pathogenetic mediators in the central nervous system: brain-periphery connections. , 1995, Neuroimmunomodulation.

[22]  G. Fantuzzi,et al.  Chlorpromazine specifically inhibits peripheral and brain TNF production, and up-regulates IL-10 production, in mice. , 1994, Immunology.