Is dermolipectomy effective in improving insulin action and lowering inflammatory markers in obese women?

Objective  Obesity is a major risk factor for coronary heart disease, and surgical treatment of obese patients as part of a multidisciplinary approach seems to provide faster results than diet therapy. The aim of this study was to evaluate the effect of dermolipectomy on insulin action and inflammatory markers in 20 obese women.

[1]  Andrew R Coggan,et al.  Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. , 2004, The New England journal of medicine.

[2]  D. Kelley Thermodynamics, liposuction, and metabolism. , 2004, The New England journal of medicine.

[3]  S. Bouret,et al.  Minireview: Leptin and development of hypothalamic feeding circuits. , 2004, Endocrinology.

[4]  T. Okura,et al.  Regional Body Composition Changes Exhibit Opposing Effects on Coronary Heart Disease Risk Factors , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[5]  W. Hanif,et al.  Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines. , 2004, Metabolism: clinical and experimental.

[6]  K. Esposito,et al.  Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women. , 2004, British journal of plastic surgery.

[7]  Sung Hee Choi,et al.  Visceral fat thickness measured by ultrasonography can estimate not only visceral obesity but also risks of cardiovascular and metabolic diseases. , 2004, The American journal of clinical nutrition.

[8]  S. Hadjadj,et al.  Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. , 2004, Diabetes.

[9]  J. Wilding Clinical evaluation of anti-obesity drugs. , 2004, Current drug targets.

[10]  D. Collen,et al.  Influence of membrane‐bound tumor necrosis factor (TNF)‐α on obesity and glucose metabolism , 2004, Journal of thrombosis and haemostasis : JTH.

[11]  P. Arner,et al.  Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance. , 2004, The Journal of clinical endocrinology and metabolism.

[12]  S. Bandinelli,et al.  Diverse Effect of Inflammatory Markers on Insulin Resistance and Insulin‐Resistance Syndrome in the Elderly , 2004, Journal of the American Geriatrics Society.

[13]  A. Aljada,et al.  Inflammation: the link between insulin resistance, obesity and diabetes. , 2004, Trends in immunology.

[14]  R. Giacco,et al.  Insulin sensitivity is increased and fat oxidation after a high-fat meal is reduced in normal-weight healthy men with strong familial predisposition to overweight , 2004, International Journal of Obesity.

[15]  M. Desai,et al.  Obesity is associated with macrophage accumulation in adipose tissue. , 2003, The Journal of clinical investigation.

[16]  A. Aljada,et al.  Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. , 2003, Diabetes.

[17]  R. Paschke,et al.  Regulation of adipocytokines and insulin resistance , 2003, Diabetologia.

[18]  C. Bogardus,et al.  Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians. , 2003, Molecular genetics and metabolism.

[19]  G. Davı̀,et al.  Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women. , 2003, The Journal of clinical endocrinology and metabolism.

[20]  C. Mantzoros,et al.  Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. , 2003, Obesity research.

[21]  P. Scherer,et al.  Printed in U.S.A. Copyright © 2003 by The Endocrine Society doi: 10.1210/en.2003-0580 Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis , 2022 .

[22]  R. Garg,et al.  Insulin resistance as a proinflammatory state: mechanisms, mediators, and therapeutic interventions. , 2003, Current drug targets.

[23]  J. Fernández-Real,et al.  Novel interactions of adiponectin with the endocrine system and inflammatory parameters. , 2003, The Journal of clinical endocrinology and metabolism.

[24]  Christopher J. Lyon,et al.  Minireview: adiposity, inflammation, and atherogenesis. , 2003, Endocrinology.

[25]  J. Fernández-Real,et al.  Insulin resistance, inflammation, and serum fatty acid composition. , 2003, Diabetes care.

[26]  B. Penninx,et al.  Visceral adipose tissue cutoffs associated with metabolic risk factors for coronary heart disease in women. , 2003, Diabetes care.

[27]  J. Meyerovitch,et al.  Relation of parental history of coronary heart disease to obesity in young adults , 2003, International Journal of Obesity.

[28]  H. Oba Large-volume tumescent anesthesia for extensive liposuction in oriental patients: lidocaine toxicity and its safe dose level. , 2003, Plastic and reconstructive surgery.

[29]  R. Touchon,et al.  Obesity and the risk for cardiovascular disease. , 2003, Preventive cardiology.

[30]  A. Tremblay,et al.  Metabolic impact of body fat distribution , 2002, Journal of endocrinological investigation.

[31]  E. Martínez-Abundis,et al.  The effects of surgically removing subcutaneous fat on the metabolic profile and insulin sensitivity in obese women after large-volume liposuction treatment. , 2002, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[32]  M. S. Platt,et al.  Deaths associated with liposuction: case reports and review of the literature. , 2002, Journal of forensic sciences.

[33]  G. Yoshino,et al.  Treatment of small dense LDL. , 2002, Journal of atherosclerosis and thrombosis.

[34]  V. Papalois,et al.  Abdominoplasty in a patient with severe obesity. , 2002, International surgery.

[35]  J. Price,et al.  Plasma fatty acids, adiposity, and variance of skeletal muscle insulin resistance in type 2 diabetes mellitus. , 2001, The Journal of clinical endocrinology and metabolism.

[36]  J. Real,et al.  Impact of obesity in primary hyperlipidemias. , 2001, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[37]  E. Bulan,et al.  Improvements in cardiovascular risk profile with large-volume liposuction: a pilot study. , 2001, Plastic and reconstructive surgery.

[38]  F. Grazer,et al.  Perioperative management of cosmetic liposuction. , 2001, Plastic and reconstructive surgery.

[39]  T. Buescher Paraspinous muscle hemorrhage as a potential source of liposuction mortality. , 2000, Plastic and reconstructive surgery.

[40]  H Wedel,et al.  Differentiated long-term effects of intentional weight loss on diabetes and hypertension. , 2000, Hypertension.

[41]  P. Barie,et al.  Large-volume liposuction complicated by retroperitoneal hemorrhage: management principles and implications for the quality improvement process. , 2000, Plastic and reconstructive surgery.

[42]  C. Bouchard,et al.  Gender difference in postprandial lipemia : importance of visceral adipose tissue accumulation. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[43]  P. Zimmet,et al.  Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation , 1998, Diabetic medicine : a journal of the British Diabetic Association.

[44]  D. Altman,et al.  STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT , 1986, The Lancet.

[45]  R. Custódio,et al.  Micro-determination of long-chain fatty acids in plasma and tissues by photometric titration. , 1980, The Analyst.

[46]  A. Beckett,et al.  AKUFO AND IBARAPA. , 1965, Lancet.

[47]  V. Dole,et al.  Microdetermination of long-chain fatty acids in plasma and tissues. , 1960, The Journal of biological chemistry.