Graves’ Disease Mechanisms: The Role of Stimulating, Blocking, and Cleavage Region TSH Receptor Antibodies
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[1] M. Giménez-Barcons,et al. Graves’ Disease TSHR-Stimulating Antibodies (TSAbs) Induce the Activation of Immature Thymocytes: A Clue to the Riddle of TSAbs Generation? , 2015, The Journal of Immunology.
[2] I. Pujol-Autonell,et al. How apoptotic β-cells direct immune response to tolerance or to autoimmune diabetes: a review , 2015, Apoptosis.
[3] R. Latif,et al. How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis. , 2013, Journal of autoimmunity.
[4] T. Gudermann,et al. TSH induces metallothionein 1 in thyrocytes via Gq/11- and PKC-dependent signaling. , 2013, Journal of molecular endocrinology.
[5] R. Latif,et al. Antibody Protection Reveals Extended Epitopes on the Human TSH Receptor , 2012, PloS one.
[6] J. Sanders,et al. Thyrotrophin receptor antibody characteristics in a woman with long‐standing Hashimoto's who developed Graves' disease and pretibial myxoedema , 2012, Clinical endocrinology.
[7] R. Latif,et al. Delineating the autoimmune mechanisms in Graves’ disease , 2012, Immunologic research.
[8] P. Pinton,et al. Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging , 2011, Journal of signal transduction.
[9] G. Ning,et al. Impairment of Regulatory Capacity of CD4+CD25+ Regulatory T Cells Mediated by Dendritic Cell Polarization and Hyperthyroidism in Graves’ Disease , 2011, The Journal of Immunology.
[10] R. Núñez Miguel,et al. Crystal structure of the TSH receptor (TSHR) bound to a blocking-type TSHR autoantibody. , 2011, Journal of molecular endocrinology.
[11] T. Ando,et al. Neutral antibodies to the TSH receptor are present in Graves' disease and regulate selective signaling cascades. , 2010, Endocrinology.
[12] T. Tagami,et al. ORIGINAL ARTICLE: Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample , 2010, Clinical endocrinology.
[13] S. Nagata,et al. Autoimmunity and the Clearance of Dead Cells , 2010, Cell.
[14] R. Paschke,et al. The hinge region: an important receptor component for GPHR function , 2010, Trends in Endocrinology & Metabolism.
[15] Hedda Wardemann,et al. B-cell tolerance checkpoints in health and autoimmunity. , 2008, Current opinion in immunology.
[16] B. Zheng,et al. Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis , 2008, Proceedings of the National Academy of Sciences.
[17] M. Niedziela,et al. Expression of Bcl-2 Family Proteins in Thyrocytes from Young Patients with Immune and Nonimmune Thyroid Diseases , 2008, Hormone Research in Paediatrics.
[18] P. Santisteban,et al. Gbetagamma dimers released in response to thyrotropin activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells. , 2008, Molecular endocrinology.
[19] B. Rapoport,et al. The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction. , 2008, Molecular endocrinology.
[20] A. Bossowski,et al. Identification of apoptotic proteins in thyroid gland from patients with Graves' disease and Hashimoto's thyroiditis , 2008, Autoimmunity.
[21] T. Ando,et al. Antibody-induced modulation of TSH receptor post-translational processing. , 2007, The Journal of endocrinology.
[22] Su He Wang,et al. The role of apoptosis in thyroid autoimmunity. , 2007, Thyroid : official journal of the American Thyroid Association.
[23] T. Blundell,et al. Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody. , 2007, Thyroid : official journal of the American Thyroid Association.
[24] J. Franklyn,et al. Tag SNP screening of the PDCD1 gene for association with Graves’ disease , 2007, Clinical endocrinology.
[25] S. Kalled,et al. Treatment of autoimmune hyperthyroidism in a murine model of Graves' disease with tumor necrosis factor-family ligand inhibitors suggests a key role for B cell activating factor in disease pathology. , 2006, Endocrinology.
[26] S. Avignone,et al. Efficacy of rituximab treatment for thyroid-associated ophthalmopathy as a result of intraorbital B-cell depletion in one patient unresponsive to steroid immunosuppression. , 2006, European journal of endocrinology.
[27] Rauf Latif,et al. Thyrotropin receptor-associated diseases: from adenomata to Graves disease. , 2005, The Journal of clinical investigation.
[28] R. N. Miguel,et al. Characteristics of a monoclonal antibody to the thyrotropin receptor that acts as a powerful thyroid-stimulating autoantibody antagonist. , 2005, Thyroid : official journal of the American Thyroid Association.
[29] T. Ando,et al. Monoclonal Antibodies to the Thyrotropin Receptor , 2005, Clinical & developmental immunology.
[30] K. Eguchi,et al. Dissecting linear and conformational epitopes on the native thyrotropin receptor. , 2004, Endocrinology.
[31] T. Blundell,et al. Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: sequence structure and function. , 2004, Thyroid : official journal of the American Thyroid Association.
[32] J. Banga,et al. Dynamics of thyroid-stimulating and -blocking antibodies to the thyrotropin receptor in a murine model of Graves' disease. , 2004, Endocrinology.
[33] T. Ando,et al. A monoclonal thyroid-stimulating antibody. , 2002, The Journal of clinical investigation.
[34] B. Rapoport,et al. Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor. , 2002, The Journal of clinical investigation.
[35] D. Aaronson,et al. A Road Map for Those Who Don't Know JAK-STAT , 2002, Science.
[36] G. Stassi,et al. Autoimmune thyroid disease: new models of cell death in autoimmunity , 2002, Nature Reviews Immunology.
[37] R. Ye. Regulation of nuclear factor κB activation by G‐protein‐coupled receptors , 2001, Journal of leukocyte biology.
[38] J. Klein,et al. The Thyrotropin (Thyroid-Stimulating Hormone) Receptor Is Expressed on Murine Dendritic Cells and on a Subset of CD45RBhigh Lymph Node T Cells: Functional Role for Thyroid-Stimulating Hormone During Immune Activation1 , 2000, The Journal of Immunology.
[39] S. Costagliola,et al. Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. , 2000, The Journal of clinical investigation.
[40] J. Mao,et al. Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[41] C. Spitzweg,et al. Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Thyrotropin Receptor Expression in Graves ’ Orbital Adipose/Connective Tissues: Potential Autoantigen in , 2022 .
[42] A. Nagasaka,et al. Changes in Free Radical Scavengers and Lipid Peroxide in Thyroid Glands of Various Thyroid Disorders , 1997, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[43] K. Burman,et al. Graves' IgG recognizes linear epitopes in the human thyrotropin receptor. , 1992, Biochemical and biophysical research communications.
[44] E. Milgrom,et al. Two-subunit structure of the human thyrotropin receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[45] N. Takasu,et al. Graves' Disease Following Hypothyroidism Due To Hashimoto's Disease: Studies Of Eight Cases , 1990, Clinical endocrinology.
[46] P. Buckland,et al. Analysis of thyrotropin receptors by photoaffinity labelling. Orientation of receptor subunits in the cell membrane. , 1985, The Biochemical journal.
[47] D. Doniach. Autoimmunity , 1965, Current Opinion in Immunology.
[48] R. Latif,et al. Characterization of thyrotropin receptor antibody-induced signaling cascades. , 2009, Endocrinology.