Astronautically Phased Mission System (APMS) has the characteristics of sophisticated system structure, complex mission profile and varied system working modes and states. For these characteristics, this paper analyses the mission profile and reliability features (sequential, correlate and dynamic) of APMS, and proposes a method of reliability synthetic modeling considering multi-feature for APMS. Applying event tree method to build baseline model for describing the sequential feature of APMS with mission profile as a main line, and then choosing some methods from dynamic fault tree, BDD, Markov chain, Petri net or Bayes network to model the initial event and intermediate event based on the events' reliability features, for describing the correlation and dynamic feature. Finally, the mission reliability model of APMS will be built by model synthesized.