Growth Factor Receptor Signaling and Metastasis of Oral Cancer

[1]  C. Dawson,et al.  Desmosomes: a role in cancer? , 2007, British Journal of Cancer.

[2]  Edward S. Kim,et al.  Epidermal growth factor receptor inhibitor-associated cutaneous toxicities: an evolving paradigm in clinical management. , 2007, The oncologist.

[3]  Jill M. Siegfried,et al.  Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer , 2007, Molecular Cancer Therapeutics.

[4]  J. Grandis,et al.  Selective Inhibition of ADAM Metalloproteases as a Novel Approach for Modulating ErbB Pathways in Cancer , 2007, Clinical Cancer Research.

[5]  Chih‐Chung Lin,et al.  TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-κB/p300 binding in human tracheal smooth muscle cells , 2007 .

[6]  M. Mahoney,et al.  Decreased Plakophilin-1 Expression Promotes Increased Motility in Head and Neck Squamous Cell Carcinoma Cells , 2007, Cell communication & adhesion.

[7]  Eun Ju Lee,et al.  The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses Proliferation and Invasion of Human Oral Squamous Carcinoma Cells via p53 Independent and MMP, uPAR Dependent Mechanism , 2007, Annals of the New York Academy of Sciences.

[8]  Jennifer L Hunt,et al.  Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting , 2006, Clinical Cancer Research.

[9]  G. Christofori,et al.  Hepatocyte growth factor induces cell scattering through MAPK/Egr‐1‐mediated upregulation of Snail , 2006, The EMBO journal.

[10]  T. Yoshizaki,et al.  Prognostic value of cell motility activation factors in patients with tongue squamous cell carcinoma. , 2006, Human pathology.

[11]  D. Bottaro,et al.  Targeting the c-Met Signaling Pathway in Cancer , 2006, Clinical Cancer Research.

[12]  R. Nicholson,et al.  Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells , 2006, Breast Cancer Research and Treatment.

[13]  Ansgar Schmidt,et al.  Differential expression of desmosomal plakophilins in various types of carcinomas: correlation with cell type and differentiation. , 2006, Human pathology.

[14]  Li‐Wha Wu,et al.  Amphiregulin as a tumor promoter for oral squamous cell carcinoma: involvement of cyclooxygenase 2. , 2006, Oral oncology.

[15]  Yaoh-Shiang Lin,et al.  Squamous cell carcinoma of the buccal mucosa: An aggressive cancer requiring multimodality treatment , 2006, Head & neck.

[16]  S. Moon,et al.  Expression of hepatocyte growth factor and c-Met in hypopharyngeal squamous cell carcinoma , 2006, Acta oto-laryngologica.

[17]  J. Kim,et al.  Prognostic value of activated Akt expression in oral squamous cell carcinoma , 2005, Journal of Clinical Pathology.

[18]  H. Lane,et al.  ERBB receptors and cancer: the complexity of targeted inhibitors , 2005, Nature Reviews Cancer.

[19]  R. Rawal,et al.  Activation of MMP‐2 and MMP‐9 in patients with oral squamous cell carcinoma , 2005, Journal of surgical oncology.

[20]  A. Margulis,et al.  E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs. , 2005, Cancer research.

[21]  K. Green,et al.  Regulation of desmosome assembly and adhesion. , 2004, Seminars in cell & developmental biology.

[22]  R. Kramer,et al.  Overexpression of c-met in oral SCC promotes hepatocyte growth factor-induced disruption of cadherin junctions and invasion. , 2004, International journal of oncology.

[23]  J. Jacobs,et al.  Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. , 2004, The New England journal of medicine.

[24]  Tony Hunter,et al.  Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. , 2003, Cancer cell.

[25]  K. Nakashiro,et al.  Gefitinib ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, mediates the inhibition of lymph node metastasis in oral cancer cells. , 2003, Cancer letters.

[26]  J. Grandis,et al.  Epidermal Growth Factor Receptor-stimulated Activation of Phospholipase Cγ-1 Promotes Invasion of Head and Neck Squamous Cell Carcinoma , 2003 .

[27]  M. Satoh,et al.  Expression of E-cadherin, α-catenin, and β-catenin in the process of lymph node metastasis in oral squamous cell carcinoma , 2003, British Journal of Cancer.

[28]  Alfonso Bellacosa,et al.  The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. , 2003, Cancer research.

[29]  Elaine Fuchs,et al.  Sticky Business Orchestrating Cellular Signals at Adherens Junctions , 2003, Cell.

[30]  Sufang Liu,et al.  Expression of e-cadherin and beta-catenin in human esophageal squamous cell carcinoma: relationships with prognosis. , 2003, World journal of gastroenterology.

[31]  M. Stack,et al.  Loss of adhesion‐regulated proteinase production is correlated with invasive activity in oral squamous cell carcinoma , 2002, Cancer.

[32]  M. Hendrix,et al.  Elevated focal adhesion kinase expression facilitates oral tumor cell invasion , 2002, Cancer.

[33]  J. Piffkó,et al.  Gains and losses of adhesion molecules (CD44, E‐cadherin, and β‐catenin) during oral carcinogenesis and tumour progression , 2002, The Journal of pathology.

[34]  Z. Chen,et al.  A lymph node metastatic mouse model reveals alterations of metastasis‐related gene expression in metastatic human oral carcinoma sublines selected from a poorly metastatic parental cell line , 2002, Cancer.

[35]  Simon C Watkins,et al.  Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in lamellipodia during EGF-induced motility. , 2002, The international journal of biochemistry & cell biology.

[36]  R. DePinho,et al.  STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. , 2002, Immunity.

[37]  I. Lorimer Mutant epidermal growth factor receptors as targets for cancer therapy. , 2002, Current cancer drug targets.

[38]  S. Giordano,et al.  MET receptor is overexpressed but not mutated in oral squamous cell carcinomas , 2001, Journal of cellular physiology.

[39]  M. Hoque,et al.  Role of HGF/c‐met system in invasion and metastasis of oral squamous cell carcinoma cells in vitro and its clinical significance , 2001, International journal of cancer.

[40]  Y. Yarden,et al.  Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.

[41]  P. Speight,et al.  Metalloproteinase expression in normal and malignant oral keratinocytes: stimulation of MMP-2 and -9 by scatter factor. , 2000, European journal of oral sciences.

[42]  M. Nakamura,et al.  Hepatocyte growth factor upregulates E1AF that induces oral squamous cell carcinoma cell invasion by activating matrix metalloproteinase genes. , 2000, Carcinogenesis.

[43]  H. Modjtahedi,et al.  Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase‐9 expression and in vitro invasion , 2000, International journal of cancer.

[44]  Seong-Doo Hong,et al.  Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential. , 2000, Oral oncology.

[45]  H. Modjtahedi,et al.  Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells. , 2000, Cancer research.

[46]  L. Kornberg,et al.  Focal adhesion kinase expression in oral cancers , 1998, Head & neck.

[47]  L. Norton,et al.  The Epidermal Growth Factor Receptor Modulates the Interaction of E-cadherin with the Actin Cytoskeleton* , 1998, The Journal of Biological Chemistry.

[48]  J. Grandis,et al.  Downmodulation of TGF‐α protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells , 1998, Journal of cellular biochemistry.

[49]  Y. Sasaguri,et al.  The significance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity. , 1996, European journal of cancer. Part B, Oral oncology.

[50]  W. Cance,et al.  Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. , 1995, Cancer research.

[51]  T. Noumi,et al.  Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters. , 1995, Oncogene.

[52]  K. Matsumoto,et al.  Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. , 1994, The Journal of biological chemistry.

[53]  S. Poulsen,et al.  Immunoreactive transforming growth factor alpha and epidermal growth factor in oral squamous cell carcinomas , 1993, The Journal of pathology.

[54]  Mahlon D. Johnson,et al.  Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[55]  R. Todd,et al.  TGF-α and EGF-receptor mRNAs in human oral cancer , 1989 .

[56]  Y. Hiraishi,et al.  Immunohistochemical expression of EGFR and p-EGFR in oral squamous cell carcinomas , 2008, Pathology & Oncology Research.

[57]  김진 The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent mechanism , 2007 .

[58]  A. Berdal,et al.  Altered plakoglobin expression at mRNA and protein levels correlates with clinical outcome in patients with oropharynx squamous carcinomas. , 2004, Human pathology.