Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice
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T. Steinfeldt | M. Schwemmle | Z. Ruzsics | C. Campos | J. Howard | S. Könen-Waisman | Catalina Alvarez | U. Müller | Shishir Singh | Mateo Murillo-León | Pia Widdershooven | I. Zimmermann | Nahleen Lukes
[1] J. Saeij,et al. Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death , 2017, Current opinion in microbiology.
[2] B. Clough,et al. The Toxoplasma Parasitophorous Vacuole: An Evolving Host-Parasite Frontier. , 2017, Trends in parasitology.
[3] L. Sibley,et al. Toxoplasma Effectors Targeting Host Signaling and Transcription , 2017, Clinical Microbiology Reviews.
[4] J. Howard,et al. The impact of Toxoplasma gondii on the mammalian genome. , 2016, Current opinion in microbiology.
[5] T. Steinfeldt,et al. The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7 , 2015, Cellular microbiology.
[6] Michael S. Behnke,et al. Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii , 2015, PLoS genetics.
[7] H. Ploegh,et al. Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination , 2015, mBio.
[8] J. Boothroyd,et al. The Toxoplasma Pseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases* , 2014, The Journal of Biological Chemistry.
[9] L. Sibley,et al. The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. , 2014, Cell host & microbe.
[10] F. Yarovinsky. Innate immunity to Toxoplasma gondii infection , 2014, Nature Reviews Immunology.
[11] L. Sibley,et al. Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse , 2014, Proceedings of the National Academy of Sciences.
[12] Xing-Quan Zhu,et al. Geographical patterns of Toxoplasma gondii genetic diversity revealed by multilocus PCR-RFLP genotyping , 2013, Parasitology.
[13] T. Steinfeldt,et al. Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse , 2013, eLife.
[14] R. Valdivia,et al. IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins , 2013, PLoS pathogens.
[15] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[16] Michael S. Behnke,et al. The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18 , 2012, PLoS pathogens.
[17] J. Boothroyd,et al. A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins , 2012, PLoS biology.
[18] M. Yaffe,et al. The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response , 2012, PLoS pathogens.
[19] P. Zhou,et al. Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages , 2012, Proceedings of the National Academy of Sciences.
[20] T. Steinfeldt,et al. The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii. , 2011, Current opinion in microbiology.
[21] S. Kaufmann,et al. The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens , 2011, PloS one.
[22] Michael S. Behnke,et al. Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases , 2011, Proceedings of the National Academy of Sciences.
[23] J. Ajioka,et al. Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America. , 2011, International journal for parasitology.
[24] J. Boothroyd,et al. Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence , 2011, Proceedings of the National Academy of Sciences.
[25] Michael S. Behnke,et al. Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. , 2010, Cell host & microbe.
[26] L. Sibley,et al. Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii , 2010, PLoS biology.
[27] J. Boothroyd,et al. Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole , 2010, Cellular microbiology.
[28] J. Ajioka,et al. Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice , 2009, PLoS genetics.
[29] Yang O. Zhao,et al. Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death , 2009, PLoS pathogens.
[30] J. Zerrahn,et al. Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6, in Vivo , 2008, Journal of Biological Chemistry.
[31] L. Sibley,et al. Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens , 2008, Cell Host & Microbe.
[32] J. Zerrahn,et al. Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii , 2008, The EMBO journal.
[33] L. Weiss,et al. The Gamma Interferon (IFN-γ)-Inducible GTP-Binding Protein IGTP Is Necessary for Toxoplasma Vacuolar Disruption and Induces Parasite Egression in IFN-γ-Stimulated Astrocytes , 2008, Infection and Immunity.
[34] R. Gilbert,et al. Ocular Sequelae of Congenital Toxoplasmosis in Brazil Compared with Europe , 2008, PLoS neglected tropical diseases.
[35] C. Su,et al. Population structure and mouse-virulence of Toxoplasma gondii in Brazil. , 2008, International journal for parasitology.
[36] A. Sher,et al. Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). , 2007, Microbes and infection.
[37] J. Howard,et al. Cell-autonomous immunity to Toxoplasma gondii in mouse and man. , 2007, Microbes and infection.
[38] Michael S. Behnke,et al. A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii , 2006, Science.
[39] J. Ajioka,et al. Polymorphic Secreted Kinases Are Key Virulence Factors in Toxoplasmosis , 2006, Science.
[40] S. Martens,et al. The interferon-inducible GTPases. , 2006, Annual review of cell and developmental biology.
[41] U. Koszinowski,et al. Common and Specific Properties of Herpesvirus UL34/UL31 Protein Family Members Revealed by Protein ComplementationAssay , 2006, Journal of Virology.
[42] I. Coppens,et al. Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages , 2006, The Journal of experimental medicine.
[43] J. Zerrahn,et al. Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases , 2005, PLoS pathogens.
[44] D. Dunn,et al. The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage , 2005, Genome Biology.
[45] A. Sher,et al. p47 GTPases Regulate Toxoplasma gondii Survival in Activated Macrophages , 2005, Infection and Immunity.
[46] C. Herrmann,et al. Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases. , 2004, Molecular cell.
[47] M. Demar,et al. Genetic diversity, clonality and sexuality in Toxoplasma gondii. , 2004, International journal for parasitology.
[48] E. Wolf,et al. Mechanisms Regulating the Positioning of Mouse p47 Resistance GTPases LRG-47 and IIGP1 on Cellular Membranes: Retargeting to Plasma Membrane Induced by Phagocytosis1 , 2004, The Journal of Immunology.
[49] T. Lehmann,et al. Variation in the structure of Toxoplasma gondii and the roles of selfing, drift, and epistatic selection in maintaining linkage disequilibria. , 2004, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
[50] M. Grigg,et al. The SRS superfamily of Toxoplasma surface proteins. , 2004, International journal for parasitology.
[51] Harvey T. McMahon,et al. The dynamin superfamily: universal membrane tubulation and fission molecules? , 2004, Nature Reviews Molecular Cell Biology.
[52] S. Parmley,et al. Serotyping of Toxoplasma gondii infections in humans using synthetic peptides. , 2003, The Journal of infectious diseases.
[53] Catherine Li,et al. High-Throughput Growth Assay for Toxoplasma gondii Using Yellow Fluorescent Protein , 2003, Antimicrobial Agents and Chemotherapy.
[54] J. Boothroyd,et al. Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease? , 2002, Current opinion in microbiology.
[55] A. Galarneau,et al. β-Lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein–protein interactions , 2002, Nature Biotechnology.
[56] C. Hunter. Faculty Opinions recommendation of Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. , 2001 .
[57] A. Sher,et al. Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection , 2001, The Journal of experimental medicine.
[58] T. Pennington,et al. Molecular typing of Toxoplasma gondii strains by GRA6 gene sequence analysis. , 2000, International journal for parasitology.
[59] A. Sher,et al. Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP , 2000 .
[60] K. Pfeffer,et al. Two families of GTPases dominate the complex cellular response to IFN-gamma. , 1998, Journal of immunology.
[61] E. Caumes,et al. Toxoplasma gondii-Associated Guillain-Barré Syndrome in an Immunocompetent Patient , 1998, Journal of Clinical Microbiology.
[62] H. Teh,et al. Specific antiviral activity demonstrated by TGTP, a member of a new family of interferon-induced GTPases. , 1998, Journal of immunology.
[63] E. Craig,et al. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. , 1996, Genetics.
[64] L. Sibley,et al. Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. , 1995, The Journal of infectious diseases.
[65] J.,et al. Detection of mycoplasma contamination in cell cultures by a mycoplasma group-specific PCR , 1994, Applied and environmental microbiology.
[66] L. David Sibley,et al. Virulent strains of Toxoplasma gondii comprise a single clonal lineage , 1992, Nature.
[67] J. Dubremetz,et al. Characterization of the protein contents of rhoptries and dense granules of Toxoplasma gondii tachyzoites by subcellular fractionation and monoclonal antibodies. , 1991, Molecular and biochemical parasitology.
[68] L. Jacobs,et al. Antigenic differences between endozoites and cystozoites of Toxoplasma gondii. , 1983, The Journal of parasitology.
[69] M. Sogorb,et al. On the gametogonic cycle of Toxoplasma gondii. , 1971, Revista do Instituto de Medicina Tropical de Sao Paulo.
[70] C. Herrmann,et al. Supplemental data Crystal Structure of IIGP 1 : A Paradigm for Interferon-Inducible p 47 Resistance GTPases , 2009 .
[71] Stephen W Michnick,et al. Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions. , 2002, Nature biotechnology.
[72] A. Sher,et al. Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[73] D. Roos,et al. Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii. , 1994, Methods in cell biology.