Insulin Rescues Retinal Neurons from Apoptosis by a Phosphatidylinositol 3-Kinase/Akt-mediated Mechanism That Reduces the Activation of Caspase-3*
暂无分享,去创建一个
T. Gardner | G. Seigel | Chad E. N. Reiter | E. Wolpert | A. Barber | D. Antonetti | Makoto Nakamura
[1] T. Gardner,et al. Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group. , 2000, Investigative Ophthalmology and Visual Science.
[2] D. Antonetti,et al. Diabetes reduces glutamate oxidation and glutamine synthesis in the retina. The Penn State Retina Research Group. , 2000, Experimental eye research.
[3] S. Aizawa,et al. Role of p53 in DNA strand break‐induced apoptosis in organotypic slice culture from the mouse cerebellum , 2000, Journal of neuroscience research.
[4] D. Kimelman,et al. Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal , 2000, The Journal of Neuroscience.
[5] T. Gardner,et al. Retinal neurodegeneration: early pathology in diabetes , 2000, Clinical & experimental ophthalmology.
[6] C. Culmsee,et al. Roles of Nuclear Factor κB in Neuronal Survival and Plasticity , 2000 .
[7] Lois E. H. Smith,et al. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor , 1999, Nature Medicine.
[8] S. R. Datta,et al. Cellular survival: a play in three Akts. , 1999, Genes & development.
[9] D. Chuang,et al. Involvement of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and p53 in Neuronal Apoptosis: Evidence That GAPDH Is Upregulated by p53 , 1999, The Journal of Neuroscience.
[10] A. Atfi,et al. Insulin Antiapoptotic Signaling Involves Insulin Activation of the Nuclear Factor κB-dependent Survival Genes Encoding Tumor Necrosis Factor Receptor-associated Factor 2 and Manganese-superoxide Dismutase* , 1999, The Journal of Biological Chemistry.
[11] M. Wax,et al. Inhibition of caspase activity in retinal cell apoptosis induced by various stimuli in vitro. , 1999, Investigative ophthalmology & visual science.
[12] M. Bennett. Mechanisms of p53-induced apoptosis. , 1999, Biochemical pharmacology.
[13] David S. Park,et al. Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons , 1999, The Journal of Neuroscience.
[14] F. McCormick,et al. Phosphoinositide 3-OH Kinase (PI3K) and PKB/Akt Delay the Onset of p53-mediated, Transcriptionally Dependent Apoptosis* , 1999, The Journal of Biological Chemistry.
[15] T. Gardner,et al. Vascular Endothelial Growth Factor Induces Rapid Phosphorylation of Tight Junction Proteins Occludin and Zonula Occluden 1 , 1999, The Journal of Biological Chemistry.
[16] E. Kandel,et al. Akt/Protein Kinase B Inhibits Cell Death by Preventing the Release of Cytochrome c from Mitochondria , 1999, Molecular and Cellular Biology.
[17] I. Jou,et al. Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I. , 1999, Journal of neurobiology.
[18] P. Cohen,et al. Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B* , 1999, The Journal of Biological Chemistry.
[19] D. Accili,et al. Insulin Stimulates Phosphorylation of the Forkhead Transcription Factor FKHR on Serine 253 through a Wortmannin-sensitive Pathway* , 1999, The Journal of Biological Chemistry.
[20] G. Seigel,et al. The golden age of retinal cell culture. , 1999, Molecular vision.
[21] Geert J. P. L. Kops,et al. Direct control of the Forkhead transcription factor AFX by protein kinase B , 1999, Nature.
[22] F. Lezoualc’h,et al. Insulin-like Growth Factor-1-mediated Neuroprotection against Oxidative Stress Is Associated with Activation of Nuclear Factor κB* , 1999, The Journal of Biological Chemistry.
[23] J. Tavaré,et al. Sustained phosphorylation and activation of protein kinase B correlates with brain-derived neurotrophic factor and insulin stimulated survival of cerebellar granule cells , 1999, Neuroscience Letters.
[24] C. Heffernan,et al. The role of protein kinase C in laminin-mediated neurite outgrowth. , 1999, Biochemical and biophysical research communications.
[25] Jun-Sub Choi,et al. Necrosis and apoptosis after retinal ischemia: involvement of NMDA-mediated excitotoxicity and p53. , 1999, Investigative ophthalmology & visual science.
[26] R. Freeman,et al. Nerve Growth Factor-Dependent Activation of NF-κB Contributes to Survival of Sympathetic Neurons , 1998, The Journal of Neuroscience.
[27] T. Torgerson,et al. Regulation of NF-κB, AP-1, NFAT, and STAT1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NF-κB p50 , 1998, The Journal of Immunology.
[28] K. Roth,et al. In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system , 1998, Cell Death and Differentiation.
[29] John Calvin Reed,et al. Regulation of cell death protease caspase-9 by phosphorylation. , 1998, Science.
[30] M. Hanson,et al. Cyclic AMP Elevation Is Sufficient to Promote the Survival of Spinal Motor Neurons In Vitro , 1998, The Journal of Neuroscience.
[31] T. Gardner,et al. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. , 1998, The Journal of clinical investigation.
[32] A. Barber,et al. Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group. , 1998, Diabetes.
[33] A. Boulton,et al. R‐Deprenyl and R‐2‐Heptyl‐N‐Methylpropargylamine Prevent Apoptosis in Cerebellar Granule Neurons Induced by Cytosine Arabinoside but Not Low Extracellular Potassium , 1998, Journal of neurochemistry.
[34] A. Atfi,et al. A Role for Nuclear Factor κB in the Antiapoptotic Function of Insulin* , 1998, The Journal of Biological Chemistry.
[35] W. Banks,et al. Transport of Insulin Across the Blood-Brain Barrier: Saturability at Euglycemic Doses of Insulin , 1997, Peptides.
[36] W. Banks,et al. Selective, Physiological Transport of Insulin Across the Blood-Brain Barrier: Novel Demonstration by Species-Specific Radioimmunoassays , 1997, Peptides.
[37] G. Seigel,et al. Inducible apoptosis-promoting activity in retinal cell-conditioned medium. , 1997, Molecular vision.
[38] M. Dragunow,et al. Cycloheximide phase‐shifts, but does not prevent, de novo Krox‐24 protein expression , 1997, Neuroreport.
[39] S. R. Datta,et al. Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery , 1997, Cell.
[40] A. Benoliel,et al. Insulin stimulates haptotactic migration of human epidermal keratinocytes through activation of NF-kappa B transcription factor. , 1997, Journal of cell science.
[41] Ge Zhou,et al. NF-κB-mediated Induction of mdr1b Expression by Insulin in Rat Hepatoma Cells* , 1997, The Journal of Biological Chemistry.
[42] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[43] Hanns Lochmüller,et al. Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons , 1996, The Journal of cell biology.
[44] S. Aizawa,et al. Involvement of p53 in DNA Strand Break‐induced Apoptosis in Postmitotic CNS Neurons , 1996 .
[45] D. Le Roith,et al. Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling? , 1996, Cytokine & growth factor reviews.
[46] G. Seigel,et al. Expression of glial markers in a retinal precursor cell line. , 1996, Molecular vision.
[47] W. Greene,et al. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation , 1996, Molecular and cellular biology.
[48] F. Bertrand,et al. Insulin Activates Nuclear Factor κB in Mammalian Cells through a Raf-1-mediated Pathway (*) , 1995, The Journal of Biological Chemistry.
[49] A. Meyer-Franke,et al. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture , 1995, Neuron.
[50] L. Barbeito,et al. Peroxynitrite‐Induced Cytotoxicity in PC12 Cells: Evidence for an Apoptotic Mechanism Differentially Modulated by Neurotrophic Factors , 1995, Journal of neurochemistry.
[51] T. Torgerson,et al. Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence (*) , 1995, The Journal of Biological Chemistry.
[52] F. Basolo,et al. p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin , 1995, The Journal of cell biology.
[53] A. Hyndman. Identification of a population of amacrine cells rich in insulin receptors. , 1993, Brain research. Developmental brain research.
[54] M. Sendtner,et al. Does oligodendrocyte survival depend on axons? , 1993, Current Biology.
[55] P. Fernyhough,et al. Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones , 1993, Brain Research.
[56] B. Pansky,et al. Preproinsulin mRNA in the rat eye. , 1993, Investigative ophthalmology & visual science.
[57] D. Munoz,et al. Effects of astrocytes, insulin and insulin-like growth factor I on the survival of motoneurons in vitro , 1992, Journal of the Neurological Sciences.
[58] G. Gupta,et al. Modulation of rat brain insulin receptor kinase activity in diabetes , 1992, Neurochemistry International.
[59] J. Wallace,et al. Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency. , 1992, Journal of molecular endocrinology.
[60] S. Rosenzweig,et al. Identification of retinal insulin receptors using site-specific antibodies to a carboxyl-terminal peptide of the human insulin receptor alpha-subunit. Up-regulation of neuronal insulin receptors in diabetes. , 1990, The Journal of biological chemistry.
[61] H. Matsumoto,et al. Release of Immunoreactive Insulin from Rat Brain Synaptosomes Under Depolarizing Conditions , 1990, Journal of neurochemistry.
[62] E. Roberson,et al. Identification of an insulin-like factor in astrocyte conditioned medium , 1988, Brain Research.
[63] G. Chader,et al. Retinal insulin receptors: localization using a polyclonal anti-insulin receptor antibody , 1988, Brain Research.
[64] G. Chader,et al. Retinal insulin receptors. 1. Structural heterogeneity and functional characterization. , 1987, Experimental eye research.
[65] M. Raizada,et al. Insulin Is Released from Rat Brain Neuronal Cells in Culture , 1986, Journal of neurochemistry.
[66] E. Engvall,et al. Substratum-binding neurite-promoting factors: relationships to laminin , 1985, Trends in Neurosciences.
[67] S. Huck. Serum-free medium for cultures of the postnatal mouse cerebellum: Only insulin is essential , 1983, Brain Research Bulletin.
[68] S. Feman,et al. The insulin concentration in human ocular fluids. , 1978, American journal of ophthalmology.
[69] R. Baserga,et al. The role of the IGF-I receptor in apoptosis. , 1997, Vitamins and hormones.
[70] P. Naeser. Insulin receptors in human ocular tissues. Immunohistochemical demonstration in normal and diabetic eyes. , 1997, Upsala journal of medical sciences.
[71] E. Almira,et al. Effect of fasting on insulin binding to hepatocytes and liver plasma membranes from rats. , 1979, Endocrinology.