Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages

[1]  S. Vogel,et al.  Transcriptional regulation of lipopolysaccharide (LPS)-induced Toll-like receptor (TLR) expression in murine macrophages: role of interferon regulatory factors 1 (IRF-1) and 2 (IRF-2) , 2006, Journal of endotoxin research.

[2]  E. Goldsmith,et al.  Determinants That Control the Specific Interactions between TAB1 and p38α , 2006, Molecular and Cellular Biology.

[3]  B. Kwon,et al.  A signal through 4‐1BB ligand inhibits receptor for activation of nuclear factor‐κB ligand (RANKL)‐induced osteoclastogenesis by increasing interferon (IFN)‐beta production , 2006, FEBS letters.

[4]  E. Latz,et al.  Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity , 2006, The EMBO journal.

[5]  Jiahuai Han,et al.  Limiting inflammatory responses during activation of innate immunity , 2005, Nature Immunology.

[6]  J. Dötsch,et al.  Regulation and Signal Transduction of Toll‐Like Receptors in Human Chorioncarcinoma Cell Lines , 2005, American journal of reproductive immunology.

[7]  Seong-Beom Lee,et al.  Differential Activation of the Transcription Factor Cyclic AMP Response Element Binding Protein (CREB) in Macrophages following Infection with Pathogenic and Nonpathogenic Mycobacteria and Role for CREB in Tumor Necrosis Factor Alpha Production , 2005, Infection and Immunity.

[8]  Hye-young Park,et al.  4-1BB-mediated immunotherapy of rheumatoid arthritis , 2004, Nature Medicine.

[9]  J. Bae,et al.  CD137-Deficient Mice Have Reduced NK/NKT Cell Numbers and Function, Are Resistant to Lipopolysaccharide-Induced Shock Syndromes, and Have Lower IL-4 Responses1 , 2004, The Journal of Immunology.

[10]  B. Beutler,et al.  Inferences, questions and possibilities in Toll-like receptor signalling , 2004, Nature.

[11]  Shizuo Akira,et al.  Toll-like receptor signalling , 2004, Nature Reviews Immunology.

[12]  P. Tobias,et al.  Cytoplasmic Domain-mediated Dimerizations of Toll-like Receptor 4 Observed by β-Lactamase Enzyme Fragment Complementation* , 2004, Journal of Biological Chemistry.

[13]  T. Watts,et al.  Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A. Galy,et al.  4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12. , 2003, Cellular immunology.

[15]  Jiahuai Han,et al.  Identification of Lps2 as a key transducer of MyD88-independent TIR signalling , 2003, Nature.

[16]  Jiahuai Han,et al.  Orphan Nuclear Receptor Nur77 Is Involved in Caspase-independent Macrophage Cell Death , 2003, The Journal of experimental medicine.

[17]  Jae-Geun Yoon,et al.  CpG DNA Induces Self and Cross-Hyporesponsiveness of RAW264.7 Cells in Response to CpG DNA and Lipopolysaccharide: Alterations in IL-1 Receptor-Associated Kinase Expression1 , 2003, The Journal of Immunology.

[18]  Jonathan Cohen The immunopathogenesis of sepsis , 2002, Nature.

[19]  W. Cao,et al.  Integrin‐nucleated Toll‐like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling , 2002, FEBS letters.

[20]  N. Suciu-Foca Faculty Opinions recommendation of Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. , 2002 .

[21]  K. Triantafilou,et al.  Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. , 2002, Trends in immunology.

[22]  Z. Lee,et al.  Immune Responses in 4-1BB (CD137)-Deficient Mice1 , 2002, The Journal of Immunology.

[23]  T. Giese,et al.  Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides1 , 2002, The Journal of Immunology.

[24]  Xuetao Cao,et al.  Involvement of ERK, p38 and NF‐κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells , 2002, Immunology.

[25]  E. Bertram,et al.  Temporal Segregation of 4-1BB Versus CD28-Mediated Costimulation: 4-1BB Ligand Influences T Cell Numbers Late in the Primary Response and Regulates the Size of the T Cell Memory Response Following Influenza Infection1 , 2002, The Journal of Immunology.

[26]  K. Takeda,et al.  Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. , 2002, International immunology.

[27]  W. Fiers,et al.  Heterotrimers Formed by Tumor Necrosis Factors of Different Species or Muteins* , 2001, The Journal of Biological Chemistry.

[28]  R. Locksley,et al.  The TNF and TNF Receptor Superfamilies Integrating Mammalian Biology , 2001, Cell.

[29]  T. Ogawa,et al.  Gene Expressions of Toll-Like Receptor 2, But Not Toll-Like Receptor 4, Is Induced by LPS and Inflammatory Cytokines in Mouse Macrophages1 , 2000, The Journal of Immunology.

[30]  L. Tong,et al.  Structural basis for signal transduction by the Toll/interleukin-1 receptor domains , 2000, Nature.

[31]  Ian F. Dunn,et al.  A Lipopolysaccharide-Specific Enhancer Complex Involving Ets, Elk-1, Sp1, and CREB Binding Protein and p300 Is Recruited to the Tumor Necrosis Factor Alpha Promoter In Vivo , 2000, Molecular and Cellular Biology.

[32]  R. Pope,et al.  REGULATION OF TNF-α EXPRESSION IN NORMAL MACROPHAGES: THE ROLE OF C/EBPβ , 2000 .

[33]  S. Akira,et al.  Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression1 , 2000, The Journal of Immunology.

[34]  M. Bachmann,et al.  Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. , 1999, Journal of immunology.

[35]  R. Andreesen,et al.  CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling. , 1998, Journal of immunology.

[36]  C. Janeway,et al.  A human homologue of the Drosophila Toll protein signals activation of adaptive immunity , 1997, Nature.

[37]  Lieping Chen,et al.  Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors , 1997, Nature Medicine.

[38]  Jiahuai Han,et al.  Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation , 1997, Nature.

[39]  N. Copeland,et al.  Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor , 1993, European journal of immunology.

[40]  K. Pollok,et al.  Inducible T cell antigen 4-1BB. Analysis of expression and function. , 1993, Journal of immunology.

[41]  B. Beutler,et al.  Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages. , 1991, Biochimica et biophysica acta.

[42]  S. Akira,et al.  A nuclear factor for IL‐6 expression (NF‐IL6) is a member of a C/EBP family. , 1990, The EMBO journal.

[43]  B. Beutler,et al.  Identity of tumour necrosis factor and the macrophage-secreted factor cachectin , 1985, Nature.

[44]  T. Watts,et al.  TNF/TNFR family members in costimulation of T cell responses. , 2005, Annual review of immunology.

[45]  J. Altman,et al.  In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses , 2002, Nature Immunology.

[46]  C. Janeway,et al.  Innate immune recognition. , 2002, Annual review of immunology.

[47]  野村 文子 Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression , 2001 .

[48]  P. Vassalli,et al.  The pathophysiology of tumor necrosis factors. , 1992, Annual review of immunology.