Engraftment of gene–modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

[1]  J. Ihle,et al.  Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells , 1994 .

[2]  M. Hatzoglou,et al.  Expression of the neomycin-resistance (neo) gene induces alterations in gene expression and metabolism. , 1994, Human gene therapy.

[3]  J. Ihle,et al.  Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients , 1993, The Lancet.

[4]  S. Orkin,et al.  Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells. , 1993, Blood.

[5]  D. Harrison.  Competitive repopulation in unirradiated normal recipients [editorial; comment] , 1993 .

[6]  P. Quesenberry,et al.  Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice. , 1993, Blood.

[7]  R. Blaese.  Development of Gene Therapy for Immunodeficiency: Adenosine Deaminase Deficiency , 1993, Pediatric Research.

[8]  A. Keating,et al.  Hematopoietic stem cells engraft in untreated transplant recipients. , 1993, Experimental hematology.

[9]  D. Valerio,et al.  Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[10]  D. Kohn,et al.  Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow. , 1992, The Journal of clinical investigation.

[11]  J. Wagner,et al.  Transplantation of umbilical cord blood after myeloablative therapy: analysis of engraftment. , 1992, Blood.

[12]  J. Kurtzberg,et al.  Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency. , 1990, The Journal of clinical investigation.

[13]  K. Weinberg,et al.  Severe combined immunodeficiency due to a specific defect in the production of interleukin-2. , 1990, The New England journal of medicine.

[14]  I. Lemischka,et al.  Clonal and systemic analysis of long-term hematopoiesis in the mouse. , 1990, Genes & development.

[15]  A. Miller,et al.  Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines. , 1989, Blood.

[16]  D. Hartl,et al.  Genetic applications of an inverse polymerase chain reaction. , 1988, Genetics.

[17]  D. Kemp,et al.  A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences. , 1988, Nucleic acids research.

[18]  H. Vonmelchner,et al.  The expression of neomycin phosphotransferase in human promyelocytic leukemia cells (HL60) delays their differentiation. , 1988 .

[19]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[20]  R. Kobayashi,et al.  Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase. , 1987, The New England journal of medicine.

[21]  A. Miller,et al.  Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production , 1986, Molecular and cellular biology.

[22]  David A. Williams,et al.  Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse , 1984, Nature.

[23]  S. Gull,et al.  A three-dimensional model of the fluid dynamics of radio-trail sources , 1984, Nature.

[24]  E. Gelfand,et al.  Severe combined immunodeficiency and adenosine deaminase deficiency. , 1973, The New England journal of medicine.

[25]  E. Giblett,et al.  Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. , 1972, Lancet.

[26]  R. Bassin,et al.  Isolation of murine sarcoma virus‐transormed mouse cells which are negative for leukemia virus from agar suspension cultures , 1970 .

[27]  D. Kohn,et al.  Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer. , 1994, Blood cells.

[28]  M. Hershfield,et al.  Enzyme Replacement Therapy with Polyethylene Glycol-Adenosine Deaminase in Adenosine Deaminase Deficiency: Overview and Case Reports of Three Patients, Including Two Now Receiving Gene Therapy , 1993, Pediatric Research.

[29]  H. Broxmeyer,et al.  Human umbilical cord blood as a source of transplantable hematopoietic stem and progenitor cells. , 1992, Current topics in microbiology and immunology.

[30]  D. Kohn,et al.  Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells. , 1990, Human gene therapy.