Sorting Nexins: New Determinants for the Development of Hypertension

Cite this article: Yang J, Armando I, Jones JE, Zeng C, Jose PA, et al. (2014) Sorting Nexins: New Determinants for the Development of Hypertension. Ann Clin Exp Hypertension 2(1): 1008. *Corresponding authors Van Anthony M. Villar, Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, 20 Penn St., Suite S003C, Baltimore, MD 21201, USA, E-mail: vvillar@medicine. umaryland.edu

[1]  Martin Fussenegger,et al.  An overview of the diverse roles of G-protein coupled receptors (GPCRs) in the pathophysiology of various human diseases. , 2013, Biotechnology advances.

[2]  J. Garvin,et al.  Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs. , 2013, American journal of physiology. Renal physiology.

[3]  Tanya M. Teslovich,et al.  Discovery and refinement of loci associated with lipid levels , 2013, Nature Genetics.

[4]  Michael E. Feigin Harnessing the genome for characterization of G‐protein coupled receptors in cancer pathogenesis , 2013, The FEBS journal.

[5]  V. A. Villar,et al.  Renal Dopamine Receptors, Oxidative Stress, and Hypertension , 2013, International journal of molecular sciences.

[6]  Foreman,et al.  The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. , 2013, JAMA.

[7]  K. Currie,et al.  Regulation of Ca(V)2 calcium channels by G protein coupled receptors. , 2013, Biochimica et biophysica acta.

[8]  T. Nakagawa,et al.  β1-Adrenergic Receptor Recycles Via a Membranous Organelle, Recycling Endosome, by Binding with Sorting Nexin27 , 2013, The Journal of Membrane Biology.

[9]  Xue-feng Wang,et al.  Expression pattern of sorting nexin 25 in temporal lobe epilepsy: A study on patients and pilocarpine-induced rats , 2013, Brain Research.

[10]  V. A. Villar,et al.  Novel role of sorting nexin 5 in renal D1 dopamine receptor trafficking and function: implications for hypertension , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  F. Di Sole,et al.  Chronic regulation of the renal Na(+)/H(+) exchanger NHE3 by dopamine: translational and posttranslational mechanisms. , 2013, American journal of physiology. Renal physiology.

[12]  S. Lipton,et al.  Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction via modulation of glutamate receptor recycling in Down syndrome , 2013, Nature Medicine.

[13]  D. Hwang,et al.  Disruption of Sorting Nexin 5 Causes Respiratory Failure Associated with Undifferentiated Alveolar Epithelial Type I Cells in Mice , 2013, PloS one.

[14]  P. A. Friedman,et al.  Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking. , 2013, Molecular endocrinology.

[15]  V. A. Villar,et al.  D5 dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1 , 2013, Hypertension Research.

[16]  Richard J. Johnson,et al.  Impaired pressure natriuresis is associated with interstitial inflammation in salt-sensitive hypertension , 2013, Current opinion in nephrology and hypertension.

[17]  B. Paw,et al.  Snx3 regulates recycling of the transferrin receptor and iron assimilation. , 2013, Cell metabolism.

[18]  V. A. Villar,et al.  Sorting Nexin 1 Loss Results in D5 Dopamine Receptor Dysfunction in Human Renal Proximal Tubule Cells and Hypertension in Mice* , 2012, The Journal of Biological Chemistry.

[19]  Michael E. Hall,et al.  Hypertension: physiology and pathophysiology. , 2012, Comprehensive Physiology.

[20]  R. Teasdale,et al.  SNX5 is essential for efficient macropinocytosis and antigen processing in primary macrophages , 2012, Biology Open.

[21]  S. Mu,et al.  The Kidney and Hypertension: Pathogenesis of Salt-Sensitive Hypertension , 2012, Current Hypertension Reports.

[22]  R. Harris,et al.  Dopamine, the Kidney, and Hypertension , 2012, Current Hypertension Reports.

[23]  T. Coffman,et al.  The kidney and hypertension: novel insights from transgenic models , 2012, Current opinion in nephrology and hypertension.

[24]  H. Korswagen,et al.  Sorting nexins provide diversity for retromer-dependent trafficking events , 2011, Nature Cell Biology.

[25]  C. Burd,et al.  Physiology and Pathology of Endosome‐to‐Golgi Retrograde Sorting , 2011, Traffic.

[26]  L. Johannes,et al.  The SNXy flavours of endosomal sorting , 2011, Nature Cell Biology.

[27]  V. A. Villar,et al.  Dopamine and renal function and blood pressure regulation. , 2011, Comprehensive Physiology.

[28]  Tien Yin Wong,et al.  Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians , 2011, Nature Genetics.

[29]  Yuguang Shi,et al.  SNX25 regulates TGF-β signaling by enhancing the receptor degradation. , 2011, Cellular signalling.

[30]  Benjamin E. L. Lauffer,et al.  SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signaling receptors , 2011, Nature Cell Biology.

[31]  S. Khundmiri,et al.  Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells. , 2011, American journal of physiology. Cell physiology.

[32]  W. Hong,et al.  Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-d-Aspartate Receptor 2C (NR2C) , 2011, Molecular and Cellular Biology.

[33]  P. Jose,et al.  Dopamine Receptors: Important Antihypertensive Counterbalance Against Hypertensive Factors , 2011, Hypertension.

[34]  W. Schlegel Signal transduction via G protein coupled receptors: a personal outlook , 2010, Journal of receptor and signal transduction research.

[35]  N. Mochizuki,et al.  Structural characteristics of BAR domain superfamily to sculpt the membrane. , 2010, Seminars in cell & developmental biology.

[36]  B. Egan,et al.  US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008. , 2010, JAMA.

[37]  Y. Namkung,et al.  Sorting nexin‐25 interacts with D1 and D2 dopamine receptors to regulate receptor expression and signaling , 2010 .

[38]  P. Michael Conn,et al.  Trafficking of G-protein-coupled receptors to the plasma membrane: insights for pharmacoperone drugs , 2010, Trends in Endocrinology & Metabolism.

[39]  F. Cappuccio,et al.  Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies , 2009, BMJ : British Medical Journal.

[40]  Kozo Nakamura,et al.  Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor. , 2009, Arthritis and rheumatism.

[41]  B. Grant,et al.  Pathways and mechanisms of endocytic recycling , 2009, Nature Reviews Molecular Cell Biology.

[42]  H. Liu,et al.  The Phox Domain of Sorting Nexin 5 Lacks Phosphatidylinositol 3-Phosphate (PtdIns(3)P) Specificity and Preferentially Binds to Phosphatidylinositol 4,5-Bisphosphate (PtdIns(4,5)P2)*♦ , 2009, The Journal of Biological Chemistry.

[43]  Andrew D. Johnson,et al.  Genome-wide association study of blood pressure and hypertension , 2009, Nature Genetics.

[44]  A. Banday,et al.  Dopamine receptors and hypertension , 2008, Current hypertension reports.

[45]  Jack T. H. Wang,et al.  A role for SNX5 in the regulation of macropinocytosis , 2008, BMC Cell Biology.

[46]  T. Wassmer,et al.  The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport. , 2008, Molecular biology of the cell.

[47]  O. Poirot,et al.  Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3. , 2008, American journal of physiology. Renal physiology.

[48]  P. Cullen Endosomal sorting and signalling: an emerging role for sorting nexins , 2008, Nature Reviews Molecular Cell Biology.

[49]  V. A. Villar,et al.  Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. , 2008, The Journal of clinical investigation.

[50]  A. Rodgers,et al.  Global burden of blood-pressure-related disease, 2001 , 2008, The Lancet.

[51]  Jiyeon Lee,et al.  Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes* , 2008, Journal of Biological Chemistry.

[52]  R. Felder,et al.  Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice. , 2008, American journal of physiology. Heart and circulatory physiology.

[53]  J. Bonifacino,et al.  Functional architecture of the retromer cargo-recognition complex , 2007, Nature.

[54]  J. Pankow,et al.  Five common gene variants identify elevated genetic risk for coronary heart disease , 2007, Genetics in Medicine.

[55]  C. T. Morgan,et al.  Absence of mutations in NR2E1 and SNX3 in five patients with MMEP (microcephaly, microphthalmia, ectrodactyly, and prognathism) and related phenotypes , 2007, BMC Medical Genetics.

[56]  Heather N. Spalding,et al.  Sorting nexin‐25, a novel member of the dopamine receptor signalplex, up‐regulates D1 and D2 dopamine receptor expression in HEK293 cells , 2007 .

[57]  R. Gainetdinov,et al.  Physiological roles of G protein-coupled receptor kinases and arrestins. , 2007, Annual review of physiology.

[58]  T. Wassmer,et al.  A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer , 2006, Journal of Cell Science.

[59]  W. Parks,et al.  Sorting Nexin 1 Down-Regulation Promotes Colon Tumorigenesis , 2006, Clinical Cancer Research.

[60]  J. Bonifacino,et al.  Interchangeable but Essential Functions of SNX1 and SNX2 in the Association of Retromer with Endosomes and the Trafficking of Mannose 6-Phosphate Receptors , 2006, Molecular and Cellular Biology.

[61]  R. Teasdale,et al.  Visualisation of macropinosome maturation by the recruitment of sorting nexins , 2006, Journal of Cell Science.

[62]  Edgar Jacoby,et al.  The 7 TM G‐Protein‐Coupled Receptor Target Family , 2006, ChemMedChem.

[63]  Cheol‐Hee Kim,et al.  Snx5, as a Mind bomb‐binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish , 2006, FEBS letters.

[64]  Stephen Magill,et al.  Inhibitory regulation of EGF receptor degradation by sorting nexin 5. , 2006, Biochemical and biophysical research communications.

[65]  S. Knuutila,et al.  Amplified, lost, and fused genes in 11q23–25 amplicon in acute myeloid leukemia, an array‐CGH study , 2006, Genes, chromosomes & cancer.

[66]  T. Magnuson,et al.  An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. , 2005, Molecular biology of the cell.

[67]  A. Notkins,et al.  The IA-2 interactome , 2005, Diabetologia.

[68]  A. Hounslow,et al.  Determinants of the endosomal localization of sorting nexin 1. , 2005, Molecular biology of the cell.

[69]  Pascal Reynier,et al.  Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors. , 2005, The Journal of clinical endocrinology and metabolism.

[70]  D. Sibley,et al.  Interaction of Angiotensin II Type 1 and D5 Dopamine Receptors in Renal Proximal Tubule Cells , 2005, Hypertension.

[71]  Bryan L Roth,et al.  Mining the Receptorome* , 2005, Journal of Biological Chemistry.

[72]  K. Reynolds,et al.  Global burden of hypertension: analysis of worldwide data , 2005, The Lancet.

[73]  A. Aviv,et al.  Urinary potassium excretion and sodium sensitivity in blacks. , 2005, Hypertension.

[74]  B. Ersbøll,et al.  A Library of 7TM Receptor C-terminal Tails , 2004, Journal of Biological Chemistry.

[75]  R. Teasdale,et al.  Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation , 2004, Journal of Cell Science.

[76]  Judith Klumperman,et al.  Sorting Nexin-1 Mediates Tubular Endosome-to-TGN Transport through Coincidence Sensing of High- Curvature Membranes and 3-Phosphoinositides , 2004, Current Biology.

[77]  J. Blangero,et al.  Principal Component for Metabolic Syndrome Risk Maps to Chromosome 4p in Mexican Americans: The San Antonio Family Heart Study , 2004, Human biology.

[78]  M. Roberts,et al.  Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin. , 2004, Molecular biology of the cell.

[79]  Norio Ohkoshi,et al.  Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration. , 2004, Molecular biology of the cell.

[80]  A. Aviv,et al.  Urinary Potassium Excretion and Sodium Sensitivity in Blacks , 2004 .

[81]  P. Soares-da-Silva,et al.  Dopamine acutely decreases type 3 Na(+)/H(+) exchanger activity in renal OK cells through the activation of protein kinases A and C signalling cascades. , 2004, European journal of pharmacology.

[82]  P. Soares-da-Silva,et al.  Distinct Signalling Cascades Downstream to Gsα Coupled Dopamine D1-like NHE3 Inhibition in Rat and Opossum Renal Epithelial Cells , 2004, Cellular Physiology and Biochemistry.

[83]  B. Peter,et al.  BAR Domains as Sensors of Membrane Curvature: The Amphiphysin BAR Structure , 2004, Science.

[84]  T. Schwartz,et al.  Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post‐endocytotic receptor targeting , 2004, FEBS letters.

[85]  D. Sibley,et al.  D5 Dopamine Receptor Knockout Mice and Hypertension , 2004, Journal of receptor and signal transduction research.

[86]  M. Katsuki,et al.  Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice. , 2003, American journal of hypertension.

[87]  H. Osswald,et al.  Dopamine D3 receptor mRNA and renal response to D3 receptor activation in spontaneously hypertensive rats. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.

[88]  Jack E. Dixon,et al.  Sorting out the cellular functions of sorting nexins , 2003, Nature Reviews Molecular Cell Biology.

[89]  D. Sibley,et al.  Mice Lacking D5 Dopamine Receptors Have Increased Sympathetic Tone and Are Hypertensive , 2002, The Journal of Neuroscience.

[90]  R. Teasdale,et al.  The Phox Homology (PX) Domain-dependent, 3-Phosphoinositide-mediated Association of Sorting Nexin-1 with an Early Sorting Endosomal Compartment Is Required for Its Ability to Regulate Epidermal Growth Factor Receptor Degradation* , 2002, The Journal of Biological Chemistry.

[91]  C. Schwartz,et al.  Sorting nexin 3 (SNX3) is disrupted in a patient with a translocation t(6;13)(q21;q12) and microcephaly, microphthalmia, ectrodactyly, prognathism (MMEP) phenotype , 2002, Journal of medical genetics.

[92]  R. Felder,et al.  Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4. , 2002, Kidney international.

[93]  C. Haft,et al.  Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1. , 2002, Molecular biology of the cell.

[94]  S. Emr,et al.  Endosomal localization and function of sorting nexin 1 , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[95]  R. Cantor,et al.  Genome Scan for Blood Pressure in Dutch Dyslipidemic Families Reveals Linkage to a Locus on Chromosome 4p , 2001, Hypertension.

[96]  D. Grandy,et al.  Adrenergic and Endothelin B Receptor-Dependent Hypertension in Dopamine Receptor Type-2 Knockout Mice , 2001, Hypertension.

[97]  L. Karlsson,et al.  A large family of endosome-localized proteins related to sorting nexin 1. , 2001, The Biochemical journal.

[98]  A. Roberts,et al.  Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases* , 2001, The Journal of Biological Chemistry.

[99]  A. Davidson,et al.  Self-assembly and binding of a sorting nexin to sorting endosomes. , 2001, Journal of cell science.

[100]  S. Ferguson,et al.  Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. , 2001, Pharmacological reviews.

[101]  N. Fineberg,et al.  Salt Sensitivity, Pulse Pressure, and Death in Normal and Hypertensive Humans , 2001, Hypertension.

[102]  P. Doris,et al.  Renal proximal tubule sodium transport and genetic mechanisms of essential hypertension , 2000, Journal of hypertension.

[103]  R. Felder,et al.  C001: Differential expression and regulation of dopamine-1(d1) and dopamine-5(d-5) receptor function in human kidney , 2000 .

[104]  S. Kajigaya,et al.  SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein. , 1999, Biochemical and biophysical research communications.

[105]  D. Haft,et al.  Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors , 1998, Molecular and Cellular Biology.

[106]  R. Felder,et al.  Effects of costimulation of dopamine D1- and D2-like receptors on renal function. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

[107]  D. Accili,et al.  Disruption of the dopamine D3 receptor gene produces renin-dependent hypertension. , 1998, The Journal of clinical investigation.

[108]  O. Moe Sodium-hydrogen exchange in renal epithelia: mechanisms of acute regulation , 1997, Current opinion in nephrology and hypertension.

[109]  R. Kurten,et al.  Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1 , 1996, Science.

[110]  D. Sibley,et al.  Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension. , 1996, The Journal of clinical investigation.

[111]  P. Hansell,et al.  The effect of dopamine receptor blockade on natriuresis is dependent on the degree of hypervolemia. , 1991, Kidney international.

[112]  R. Felder,et al.  Intrarenal dopamine acts at the dopamine‐1 receptor to control renal function , 1988, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

[113]  D. Sibley,et al.  Lack of renal dopamine D5 receptors promotes hypertension. , 2011, Journal of the American Society of Nephrology : JASN.

[114]  W. Elliott US Trends in Prevalence, Awareness, Treatment, and Control of Hypertension, 1988-2008 , 2011 .

[115]  D. Sibley,et al.  D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

[116]  F. Maxfield,et al.  Endocytic recycling , 2004, Nature Reviews Molecular Cell Biology.

[117]  M. von Zastrow Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway. , 2003, Life sciences.

[118]  A. Aperia Intrarenal dopamine: a key signal in the interactive regulation of sodium metabolism. , 2000, Annual review of physiology.

[119]  M. Lokhandwala,et al.  An impairment of renal tubular DA-1 receptor function as the causative factor for diminished natriuresis to volume expansion in spontaneously hypertensive rats. , 1992, Clinical and experimental hypertension. Part A, Theory and practice.