Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
暂无分享,去创建一个
Q. Tong | Shaday Michán | L. Goodyear | Y. Manabe | J. Carmona | Keyun Chen | O. Palacios | Jack Lee Ward Iii
[1] Ling Liu,et al. Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti‐aging and metabolic effects of sirtuins , 2009, Proteomics.
[2] Takashi Nakagawa,et al. SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle , 2009, Cell.
[3] P. Puigserver,et al. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity , 2009, Nature.
[4] S. Farmer,et al. Obesity: Be cool, lose weight , 2009, Nature.
[5] E. Verdin,et al. A New Splice Variant of the Mouse SIRT3 Gene Encodes the Mitochondrial Precursor Protein , 2009, PloS one.
[6] G. Remuzzi,et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. , 2009, The Journal of clinical investigation.
[7] David P. Carney,et al. Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3 , 2009, Protein science : a publication of the Protein Society.
[8] A. Sureda,et al. Antioxidant regulatory mechanisms in neutrophils and lymphocytes after intense exercise , 2009, Journal of sports sciences.
[9] Ian R. Lanza,et al. Endurance Exercise as a Countermeasure for Aging , 2008, Diabetes.
[10] C. Steegborn,et al. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. , 2008, Journal of molecular biology.
[11] Shiwei Song,et al. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis , 2008, Proceedings of the National Academy of Sciences.
[12] C. Deng,et al. SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression , 2008, International journal of biological sciences.
[13] G. López-Lluch,et al. Mitochondrial biogenesis and healthy aging , 2008, Experimental Gerontology.
[14] N. Sundaresan,et al. SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70 , 2008, Molecular and Cellular Biology.
[15] E. Hoffman,et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. , 2008, Developmental cell.
[16] W. C. Hallows,et al. Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase. , 2008, The Biochemical journal.
[17] J. N. Spelbrink,et al. The human SIRT3 protein deacetylase is exclusively mitochondrial. , 2008, The Biochemical journal.
[18] L. Guarente. Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins? , 2008, Cell.
[19] S. Gygi,et al. An AMPK-FOXO Pathway Mediates Longevity Induced by a Novel Method of Dietary Restriction in C. elegans , 2007, Current Biology.
[20] Eric Verdin,et al. Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation , 2007, Molecular and Cellular Biology.
[21] Dudley Lamming,et al. Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival , 2007, Cell.
[22] N. Fujii,et al. Skeletal Muscle Adaptation to Exercise Training , 2007, Diabetes.
[23] David Sinclair,et al. Sirtuins in mammals: insights into their biological function. , 2007, The Biochemical journal.
[24] P. Puigserver,et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α , 2007, The EMBO journal.
[25] L. Guarente,et al. Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction. , 2006, Genes & development.
[26] P. Shiels,et al. Altered sirtuin expression is associated with node-positive breast cancer , 2006, British Journal of Cancer.
[27] F. Alt,et al. SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells , 2006, Cell.
[28] Eric Verdin,et al. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 , 2006, Proceedings of the National Academy of Sciences.
[29] W. C. Hallows,et al. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases , 2006, Proceedings of the National Academy of Sciences.
[30] B. Spiegelman,et al. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. , 2006, Endocrine reviews.
[31] D. Kelly,et al. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. , 2006, The Journal of clinical investigation.
[32] T. Ben-Hur,et al. Nutritional Status, Cognition, and Survival , 2005, Journal of Biological Chemistry.
[33] G. Muscat,et al. Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease. , 2005, The international journal of biochemistry & cell biology.
[34] Izumi Horikawa,et al. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. , 2005, Molecular biology of the cell.
[35] Q. Tong,et al. SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes* , 2005, Journal of Biological Chemistry.
[36] L. Guarente,et al. Calorie Restriction— the SIR2 Connection , 2005, Cell.
[37] C. Franceschi,et al. A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. , 2005, Genomics.
[38] J. Apfeld,et al. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. , 2004, Genes & development.
[39] E. Verdin,et al. Sirtuins: Sir2-related NAD-dependent protein deacetylases , 2004, Genome Biology.
[40] David Carling,et al. Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade , 2003 .
[41] N. Ruderman,et al. Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. , 2003, Diabetes.
[42] G. Shulman,et al. Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle* , 2002, The Journal of Biological Chemistry.
[43] G. Shulman,et al. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[44] A. Feinberg,et al. SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[45] E. Verdin,et al. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase , 2002, The Journal of cell biology.
[46] G. Shulman,et al. Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis. , 2001, American journal of physiology. Endocrinology and metabolism.
[47] Marc Montminy,et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 , 2001, Nature.
[48] D J Campbell,et al. AMP-activated protein kinase, super metabolic regulator. , 2001, Biochemical Society transactions.
[49] O. Ljungqvist,et al. Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle. , 2000, Biochemical and biophysical research communications.
[50] V. Mootha,et al. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1 , 1999, Cell.
[51] Christophe Person,et al. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells , 1998, Nature.
[52] D. Hardie,et al. Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. , 1997, The American journal of physiology.
[53] K. Clément,et al. Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women. , 2008, The Journal of clinical endocrinology and metabolism.
[54] L. Kubin,et al. Journal of Applied Physiology publishes original papers that deal with diverse area of research in applied , 2008 .
[55] G. Passarino,et al. Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13. , 2007, Genomics.
[56] D. Sinclair,et al. Sirtuins: a conserved key unlocking AceCS activity. , 2007, Trends in biochemical sciences.
[57] D. Hardie,et al. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. , 2005, Cell metabolism.
[58] M. McCarty. Chronic activation of AMP-activated kinase as a strategy for slowing aging. , 2004, Medical hypotheses.
[59] Jiandie D. Lin,et al. An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[60] V. Ogryzko,et al. Immunoaffinity purification of mammalian protein complexes. , 2003, Methods in enzymology.
[61] Jiandie D. Lin,et al. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. , 2002, Nature.