Texture based classification of the severity of mitral regurgitation

Clinically, the severity of valvular regurgitation is assessed by manual tracing of the regurgitant jet in the respective chambers. This work presents a computer-aided diagnostic (CAD) system for the assessment of the severity of mitral regurgitation (MR) based on image processing that does not require the intervention of the radiologist or clinician. Eight different texture feature sets from the regurgitant area (selected through an arbitrary criterion) have been used in the present approach. First order statistics have been used initially, however, observing their limitations, the other texture features such as spatial gray level difference matrix, gray level difference statistics, neighborhood gray tone difference matrix, statistical feature matrix, Laws' textures energy measure, fractal dimension texture analysis and Fourier power spectrum have additionally been used. For the classification task a supervised classifier i.e., support vector machine has been used in the present approach. The classification accuracy has been improved significantly by using these texture features in combination, in comparison to when fed individually as input to the classifier. The classification accuracy of 95.65±1.09, 95.65±1.09 and 95.36±1.13 has been obtained in apical two chamber, apical four chamber and parasternal long axis views, respectively. Therefore, the results of this paper indicate that the proposed CAD system may effectively assist the radiologists in establishing (confirming) the MR stages, namely, mild, moderate and severe.

[1]  DuWayne L. Willett,et al.  Assessment of mitral regurgitation severity by Doppler color flow mapping of the vena contracta. , 1996, Circulation.

[2]  Jun-bo Ge,et al.  [Initial experience of treating patients with severe mitral regurgitation with transcatheter mitral valve edge-to-edge repair in China]. , 2013, Zhonghua xin xue guan bing za zhi.

[3]  Chia-Hua Ho,et al.  Recent Advances of Large-Scale Linear Classification , 2012, Proceedings of the IEEE.

[4]  Robert King,et al.  Textural features corresponding to textural properties , 1989, IEEE Trans. Syst. Man Cybern..

[5]  Jitendra Virmani,et al.  SVM-Based Characterization of Liver Ultrasound Images Using Wavelet Packet Texture Descriptors , 2013, Journal of Digital Imaging.

[6]  Chuan-Yu Chang,et al.  Application of support-vector-machine-based method for feature selection and classification of thyroid nodules in ultrasound images , 2010, Pattern Recognit..

[7]  Ruey-Feng Chang,et al.  Classification of breast ultrasound images using fractal feature. , 2005, Clinical imaging.

[8]  U. Rajendra Acharya,et al.  Application of wavelet techniques for cancer diagnosis using ultrasound images: A Review , 2016, Comput. Biol. Medicine.

[9]  Bernhard Schölkopf,et al.  Comparing support vector machines with Gaussian kernels to radial basis function classifiers , 1997, IEEE Trans. Signal Process..

[10]  Xiaoying Tang,et al.  Texture analysis and classification of ultrasound liver images. , 2014, Bio-medical materials and engineering.

[11]  Chih-Jen Lin,et al.  LIBSVM: A library for support vector machines , 2011, TIST.

[12]  Robert M. Haralick,et al.  Textural Features for Image Classification , 1973, IEEE Trans. Syst. Man Cybern..

[13]  Koby Crammer,et al.  On the Learnability and Design of Output Codes for Multiclass Problems , 2002, Machine Learning.

[14]  Adam C. Winstanley,et al.  Invariant optimal feature selection: A distance discriminant and feature ranking based solution , 2008, Pattern Recognit..

[15]  Bernhard E. Boser,et al.  A training algorithm for optimal margin classifiers , 1992, COLT '92.

[16]  Kenneth I. Laws,et al.  Rapid Texture Identification , 1980, Optics & Photonics.

[17]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[18]  N. Nanda,et al.  Color Doppler assessment of mitral regurgitation with orthogonal planes. , 1987, Circulation.

[19]  J. Hair Multivariate data analysis , 1972 .

[20]  M. L. Dewal,et al.  Multiresolution local binary pattern variants based texture feature extraction techniques for efficient classification of microscopic images of hardwood species , 2015, Appl. Soft Comput..

[21]  D Patel,et al.  Doppler color flow "proximal isovelocity surface area" method for estimating volume flow rate: effects of orifice shape and machine factors. , 1991, Journal of the American College of Cardiology.

[22]  D J Sahn,et al.  Quantification of valvular regurgitation by Doppler echocardiography. , 1991, Circulation.

[23]  Trevor Hastie,et al.  The Elements of Statistical Learning , 2001 .

[24]  B Lüderitz,et al.  Color-coded Doppler imaging of the vena contracta as a basis for quantification of pure mitral regurgitation. , 1994, The American journal of cardiology.

[25]  Fuhui Long,et al.  Feature selection based on mutual information criteria of max-dependency, max-relevance, and min-redundancy , 2003, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[26]  P. Grayburn,et al.  Grading severity of mitral regurgitation by echocardiography: science or art? , 2010, JACC. Cardiovascular imaging.

[27]  B Lüderitz,et al.  Multiplane transesophageal echocardiographic assessment of mitral regurgitation by Doppler color flow mapping of the vena contracta. , 1994, The American journal of cardiology.

[28]  Elif Derya Übeyli,et al.  Multiclass Support Vector Machines for EEG-Signals Classification , 2007, IEEE Trans. Inf. Technol. Biomed..

[29]  Benoit B. Mandelbrot,et al.  Fractal Geometry of Nature , 1984 .

[30]  V. Rigolin,et al.  Two and three dimensional echocardiography for pre-operative assessment of mitral valve regurgitation , 2014, Cardiovascular Ultrasound.

[31]  S. Kaddoura Echo Made Easy , 2001 .

[32]  Yung-Chang Chen,et al.  Texture features for classification of ultrasonic liver images , 1992, IEEE Trans. Medical Imaging.

[33]  Constantinos S. Pattichis,et al.  Texture-based classification of atherosclerotic carotid plaques , 2003, IEEE Transactions on Medical Imaging.

[34]  Denis Bouchard,et al.  Predicting recurrent mitral regurgitation after mitral valve repair for severe ischemic mitral regurgitation. , 2015, The Journal of thoracic and cardiovascular surgery.

[35]  Konstantina S. Nikita,et al.  Comparison of Multiresolution Features for Texture Classification of Carotid Atherosclerosis From B-Mode Ultrasound , 2011, IEEE Transactions on Information Technology in Biomedicine.

[36]  Savita Gupta,et al.  An information fusion based method for liver classification using texture analysis of ultrasound images , 2014, Inf. Fusion.

[37]  Hidehiro Kaneko,et al.  Functional mitral regurgitation and left ventricular systolic dysfunction in the recent era of cardiovascular clinical practice, an observational cohort study , 2014, Hypertension Research.

[38]  Azriel Rosenfeld,et al.  A Comparative Study of Texture Measures for Terrain Classification , 1975, IEEE Transactions on Systems, Man, and Cybernetics.

[39]  Tzu-Tsung Wong,et al.  Performance evaluation of classification algorithms by k-fold and leave-one-out cross validation , 2015, Pattern Recognit..

[40]  Joan S. Weszka,et al.  A survey of threshold selection techniques , 1978 .

[41]  V Hombach,et al.  New method for accurate calculation of regurgitant flow rate based on analysis of Doppler color flow maps of the proximal flow field. Validation in a canine model of mitral regurgitation with initial application in patients. , 1996, Journal of the American College of Cardiology.

[42]  Lars Kai Hansen,et al.  Quantitative analysis of ultrasound B-mode images of carotid atherosclerotic plaque: correlation with visual classification and histological examination , 1998, IEEE Transactions on Medical Imaging.

[43]  Ling Zhang,et al.  Automated breast cancer detection and classification using ultrasound images: A survey , 2015, Pattern Recognit..

[44]  H Kratzer,et al.  Quantitation of aortic regurgitation by colour coded cross-sectional Doppler echocardiography. , 1988, European heart journal.

[45]  Gunnar Rätsch,et al.  An introduction to kernel-based learning algorithms , 2001, IEEE Trans. Neural Networks.

[46]  Mario J. Garcia,et al.  Left Ventricular Early Inflow–Outflow Index: A Novel Echocardiographic Indicator of Mitral Regurgitation Severity , 2015, Journal of the American Heart Association.

[47]  J L Rey,et al.  Assessment of severity of mitral regurgitation by measuring regurgitant jet width at its origin with transesophageal Doppler color flow imaging. , 1992, Circulation.

[48]  S Chandra,et al.  Volumetric measurement of the anatomic regurgitant orifice area in mitral regurgitation: Comparison with two-dimensional flow convergence analysis , 2009, 2009 36th Annual Computers in Cardiology Conference (CinC).

[49]  C.P. Loizou,et al.  Comparative evaluation of despeckle filtering in ultrasound imaging of the carotid artery , 2005, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.