Postnatal developmental expression of calbindin, calretinin and parvalbumin in mouse main olfactory bulb.

The distribution of calbindin, calretinin and parvalbumin during the development of the mouse main olfactory bulb (MOB) was studied using immunohistochemistry techniques. The results are as follows: (1) calbindin-immunoreactive profiles were mainly located in the glomerular layer, and few large calbindin-immunoreactive cells were found in the subependymal layer of postnatal day 10 (P10) to postnatal day 40 (P40) mice; (2) no calbindin was detected in the mitral cell layer at any stage; (3) calretinin-immunoreactive profiles were present in all layers of the main olfactory bulb at all stages, especially in the olfactory nerve layer, glomerular layer and granule cell layer; (4) parvalbumin-immunoreactive profiles were mainly located in the external plexiform layer (except for P10 mice); (5) weakly stained parvalbumin-immunoreactive profiles were present in the glomerular layer at all stages; and (6) no parvalbumin was detected in the mitral cell layer at any stage.

[1]  J. G. Briñón,et al.  Calbindin D-28k-positive neurons in the rat olfactory bulb , 1992, Cell and Tissue Research.

[2]  T. Kosaka,et al.  Calcium-binding protein parvalbumin-immunoreactive neurons in the rat olfactory bulb , 2004, Experimental Brain Research.

[3]  I. Hwang,et al.  Age-related changes of parvalbumin immunoreactive neurons in the rat main olfactory bulb. , 2003, Molecules and cells.

[4]  M. Halpern,et al.  Calbindin D28K immunoreactive neurons in vomeronasal organ and their projections to the accessory olfactory bulb in the rat , 2003, Brain Research.

[5]  D. Berlau,et al.  Comparative study of aging in the mouse olfactory bulb , 2002, The Journal of comparative neurology.

[6]  I. Hwang,et al.  Age-related change of calbindin D-28k immunoreactive neurons in the rat main olfactory bulb , 2002, Neuroscience Letters.

[7]  C. Crespo,et al.  Parvalbumin-containing interneurons do not innervate granule cells in the olfactory bulb , 2001, Neuroreport.

[8]  K. Kishi,et al.  Calbindin-D28k and calretinin immunoreactive neurons in the olfactory bulb of the musk shrew, Suncus murinus. , 2001, Brain research. Developmental brain research.

[9]  P. Brunjes,et al.  Focal denervation alters cellular phenotypes and survival in the rat olfactory bulb: A developmental analysis , 2000, The Journal of comparative neurology.

[10]  H. Hidaka,et al.  Coexpression of neurocalcin with other calcium‐binding proteins in the rat main olfactory bulb , 1999, The Journal of comparative neurology.

[11]  T. Kosaka,et al.  How simple is the organization of the olfactory glomerulus?: the heterogeneity of so-called periglomerular cells , 1998, Neuroscience Research.

[12]  Y. Kimura,et al.  [Calretinin immunoreactivity in olfactory bulb and mucosa in mice]. , 1998, Nihon Jibiinkoka Gakkai kaiho.

[13]  B. Philpot,et al.  Activity‐dependent regulation of calcium‐binding proteins in the developing rat olfactory bulb , 1997, The Journal of comparative neurology.

[14]  J. G. Briñón,et al.  Calretinin- and parvalbumin-immunoreactive neurons in the rat main olfactory bulb do not express NADPH-diaphorase activity , 1997, Journal of Chemical Neuroanatomy.

[15]  J. G. Briñón,et al.  Calcium-binding proteins in the periglomerular region of typical and atypical olfactory glomeruli , 1997, Brain Research.

[16]  J. G. Briñón,et al.  Calcium-binding proteins in the periglomerular region of typical and typical olfactory glomeruli. , 1997, Brain research.

[17]  T. Kosaka,et al.  Electron microscopic serial-sectioning/reconstruction study of parvalbumin-containing neurons in the external plexiform layer of the rat olfactory bulb , 1996, Neuroscience.

[18]  R. Pochet,et al.  Calmodulin, calbindin-D28k, calretinin and neurocalcin in rat olfactory bulb during postnatal development. , 1995, Brain research. Developmental brain research.

[19]  F. Wouterlood,et al.  Calretinin-immunoreactivity in mitral cells of the rat olfactory bulb , 1995, Brain Research.

[20]  T. Kosaka,et al.  Synaptic contacts between mitral/tufted cells and GABAergic neurons containing calcium-binding protein parvalbumin in the rat olfactory bulb, with special reference to reciprocal synapses between them , 1994, Brain Research.

[21]  D. Jacobowitz,et al.  Immunocytochemical localization of calretinin in the forebrain of the rat , 1991, The Journal of comparative neurology.

[22]  F. Valverde,et al.  Structure of the olfactory bulb of the hedgehog (Erinaceus europaeus): A Golgi study of the intrinsic organization of the superficial layers , 1990, The Journal of comparative neurology.

[23]  J. A. Carlos,et al.  Vasoactive intestinal polypeptide-immunoreactive neurons in the main olfactory bulb of the hedgehog (Erinaceus europaeus) , 1989, Neuroscience Letters.

[24]  T. Kosaka,et al.  An aspect of the organization of the GABAergic system in the rat main olfactory bulb: laminar distribution of immunohistochemically defined subpopulations of GABAergic neurons , 1987, Brain Research.

[25]  F. Valverde,et al.  Structure of the olfactory bulb of the hedgeho (erinaceus europaeus): Description of cell types in the granular layer , 1986, The Journal of comparative neurology.

[26]  L. Orci,et al.  Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system , 1984, Brain Research.