A heuristic program for evaluating histocompatibility typing data.

Abstract A heuristic program has been developed which evaluates the results of histocompatibility typing. It is intended for use in retrospective studies involving large volumes of data. The program is inexpensive to run and is not dependent on a particular set of typing sera. This paper describes its algorithm and operation in detail. The program must first be initialized, primarily by supplying weights which characterize the typing sera being used. It then analyzes typing data in two passes; the first pass processes “obvious” cases, and the second processes the remainder in a more sophisticated manner. Output is provided in forms suitable for further computer processing as well as human examination.