Single-Channel Impedance Plethysmography Neck Patch Device for Unobtrusive Wearable Cardiovascular Monitoring

Background: Wearable and unobtrusive sensing devices are rapidly evolving for long-term cardiovascular monitoring. However, most of the cardiovascular device requires multi-channel physiological signals acquisition, especially in continuous blood pressure (BP) measurement using pulse transition time (PTT) based methods. The multi-devices implementation could impede wearable applications. Objective: This study developed a wearable neck patch device using single-channel impedance plethysmography (IPG) sensing for cardiovascular monitoring, including continuous BP and heart rate (HR) measurement. Methods: IPG-based BP model was derived based on the Bramwell-Hill equation. A patch IPG device was designed and installed above the carotid artery of the subject neck. To validate the BP and HR functions of our device, the Bland-Altman plots were performed to evaluate the estimation error between the reference and the proposed devices within 20 healthy subjects. Results: The BP performance indicates that systolic BP (SBP) estimation error was −0.16 ± 2.97 mmHg and 2.43 ± 1.71 mmHg in terms of mean error (ME) and mean absolute error (MAE), and 0.09 ± 3.30 mmHg and 2.83 ± 1.68 mmHg for diastolic BP (DBP) estimation. Moreover, the HR accuracy has the ME and MAE of 0.02 ± 0.17 bpm and 0.14 ± 0.08 bpm; mean percentage error (MPE) and mean absolute percentage error (MAPE) obtained 0.04 ± 0.23 % and 0.19 ± 0.12 %. Based on statistical results, the BP and HR function of our device satisfied with AAMI/ANSI criteria below 5 ± 8 mmHg and ± 5 bpm or ± 10%. Conclusion: This study implemented a wearable neck patch device with single-channel IPG acquisition that provided two significant cardiovascular parameters of continuous BP and HR, and its performance agreed with standard criteria based on validation with reference sensors. Significance: The proposed proof-of-concept IPG neck patch device has a high potential for wearable applications and low-cost manufacturing in cardiovascular monitoring.

[1]  Luca Mainardi,et al.  Chest Wearable Apparatus for Cuffless Continuous Blood Pressure Measurements Based on PPG and PCG Signals , 2020, IEEE Access.

[2]  Roozbeh Jafari,et al.  Noninvasive Cuffless Blood Pressure Estimation Using Pulse Transit Time and Impedance Plethysmography , 2019, IEEE Transactions on Biomedical Engineering.

[3]  Ming-Zher Poh,et al.  Validation of a Standalone Smartphone Application for Measuring Heart Rate Using Imaging Photoplethysmography. , 2017, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[4]  PohMing-Zher,et al.  Validation of a Standalone Smartphone Application for Measuring Heart Rate Using Imaging Photoplethysmography , 2017 .

[5]  Behnam Askarian,et al.  Cuff-Less Blood Pressure Monitoring System Using Smartphones , 2020, IEEE Access.

[6]  Dae-Geun Jang,et al.  Pulse Transit Time-Pulse Wave Analysis Fusion Based on Wearable Wrist Ballistocardiogram for Cuff-Less Blood Pressure Trend Tracking , 2020, IEEE Access.

[7]  Tushar Kanti Bera,et al.  Bioelectrical Impedance Methods for Noninvasive Health Monitoring: A Review , 2014, Journal of medical engineering.

[8]  Roozbeh Jafari,et al.  An Accurate Bioimpedance Measurement System for Blood Pressure Monitoring , 2018, Sensors.

[9]  Qifa Zhou,et al.  Monitoring of the central blood pressure waveform via a conformal ultrasonic device , 2018, Nature Biomedical Engineering.

[10]  Guy Carrault,et al.  A New Wearable Device for Blood Pressure Estimation Using Photoplethysmogram , 2019, Sensors.

[11]  Javier Reina-Tosina,et al.  Fundamentals, Recent Advances, and Future Challenges in Bioimpedance Devices for Healthcare Applications , 2019, J. Sensors.

[12]  Basic Physiology for Anaesthetists: Arterial pressure waveforms , 2015 .

[13]  Shruti T. Pistolwala,et al.  Noninvasive Carotid Artery Pulse Monitoring System , 2019 .

[14]  Haipeng Liu,et al.  Cuffless Blood Pressure Estimation Using Single Channel Photoplethysmography: A Two-Step Method , 2020, IEEE Access.

[15]  Guang-Zhong Yang,et al.  A Smart Wireless Ear-Worn Device for Cardiovascular and Sweat Parameter Monitoring During Physical Exercise: Design and Performance Results , 2019, Sensors.

[16]  T. Togawa,et al.  Continuous estimation of systolic blood pressure using the pulse arrival time and intermittent calibration , 2000, Medical and Biological Engineering and Computing.

[17]  Roozbeh Jafari,et al.  Cuffless Blood Pressure Monitoring from an Array of Wrist Bio-Impedance Sensors Using Subject-Specific Regression Models: Proof of Concept , 2019, IEEE Transactions on Biomedical Circuits and Systems.

[18]  Shien-Fong Lin,et al.  Wearable Piezoelectric-Based System for Continuous Beat-to-Beat Blood Pressure Measurement , 2020, Sensors.

[19]  J. Nyboer,et al.  Electrical Impedance Plethysmography: A Physical and Physiologic Approach to Peripheral Vascular Study , 1950, Circulation.