Intraclonal competition limits the fate determination of regulatory T cells in the thymus
暂无分享,去创建一个
A. Rudensky | C. Hsieh | Yuqiong Liang | K. Forbush | C. Lio | S. Lathrop | J. Bautista | Jingqin R Luo
[1] C. Hsieh,et al. Antigen-specific peripheral shaping of the natural regulatory T cell population , 2008, The Journal of experimental medicine.
[2] H. Yee,et al. Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. , 2008, Immunity.
[3] T. Nomura,et al. Regulatory T Cells and Immune Tolerance , 2008, Cell.
[4] C. Hsieh,et al. A two-step process for thymic regulatory T cell development. , 2008, Immunity.
[5] Christophe Benoist,et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. , 2007, Immunity.
[6] Ansuman T. Satpathy,et al. Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes , 2007, Proceedings of the National Academy of Sciences.
[7] Nagendra Singh,et al. Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells. , 2007, Immunity.
[8] C. Benoist,et al. Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4+ T Cells1 , 2007, The Journal of Immunology.
[9] T. Chatila,et al. Regulatory T cell development in the absence of functional Foxp3 , 2007, Nature Immunology.
[10] P. Bousso,et al. Competition for antigen determines the stability of T cell–dendritic cell interactions during clonal expansion , 2007, Proceedings of the National Academy of Sciences.
[11] Ximing J. Yang,et al. Tumor Evasion of the Immune System by Converting CD4+CD25− T Cells into CD4+CD25+ T Regulatory Cells: Role of Tumor-Derived TGF-β , 2007, The Journal of Immunology.
[12] Vincent C. Manganiello,et al. Foxp3-dependent programme of regulatory T-cell differentiation , 2007, Nature.
[13] A. Rudensky,et al. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice , 2007, Nature Immunology.
[14] C. Loddenkemper,et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease , 2007, The Journal of experimental medicine.
[15] M. Farrar,et al. IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells1 , 2007, The Journal of Immunology.
[16] A. Hayday,et al. Early events in the thymus affect the balance of effector and regulatory T cells , 2006, Nature.
[17] L. Ignatowicz,et al. Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. , 2006, Immunity.
[18] B. Kyewski,et al. Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[19] A. Khoruts,et al. Naïve and Memory CD4+ T Cell Survival Controlled by Clonal Abundance , 2006, Science.
[20] A. Rudensky,et al. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires , 2006, Nature Immunology.
[21] Pau Serra,et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice , 2006, Nature Immunology.
[22] J. Lohr,et al. Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen , 2005, The Journal of experimental medicine.
[23] D. Hudrisier,et al. Molecular Signature of Recent Thymic Selection Events on Effector and Regulatory CD4+ T Lymphocytes1 , 2005, The Journal of Immunology.
[24] A. Rudensky,et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. , 2005, Immunity.
[25] A. Singer,et al. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 , 2005, Nature Immunology.
[26] C. Benoist,et al. Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells , 2004, The Journal of experimental medicine.
[27] L. Chatenoud,et al. Unique role of CD4+CD62L+ regulatory T cells in the control of autoimmune diabetes in T cell receptor transgenic mice , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[28] A. Rudensky,et al. Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. , 2004, Immunity.
[29] H. von Boehmer,et al. In Vivo Instruction of Suppressor Commitment in Naive T Cells , 2004, The Journal of experimental medicine.
[30] B. Fowlkes,et al. The influence of the thymic environment on the CD4-versus-CD8 T lineage decision , 2003, Nature Immunology.
[31] K. Murali‐Krishna. Faculty Opinions recommendation of Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition. , 2003 .
[32] A. Troy,et al. Cutting Edge: Homeostatic Proliferation of Peripheral T Lymphocytes Is Regulated by Clonal Competition1 , 2003, The Journal of Immunology.
[33] E. Raines,et al. Gene therapy of apolipoprotein E-deficient mice using a novel macrophage-specific retroviral vector. , 2003, Blood.
[34] A. Khoruts,et al. Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[35] T. Malek,et al. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. , 2002, Immunity.
[36] L. Klein,et al. Origin of regulatory T cells with known specificity for antigen , 2002, Nature Immunology.
[37] M. Jordan. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide , 2001, Nature Immunology.
[38] A. Rudensky,et al. Competition for Specific Intrathymic Ligands Limits Positive Selection in a TCR Transgenic Model of CD4+ T Cell Development1 , 2000, The Journal of Immunology.
[39] F. Otsuka,et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. , 1999, Journal of immunology.
[40] J. Lafaille,et al. Regulatory Cd4 Ϩ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis , 1998 .
[41] W. Heath,et al. Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements , 1998, Immunology and cell biology.
[42] J. Miller,et al. Constitutive class I-restricted exogenous presentation of self antigens in vivo , 1996, The Journal of experimental medicine.
[43] D. Kioussis,et al. Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. , 1995, Journal of immunological methods.
[44] R. Coffman,et al. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. , 1993, International immunology.
[45] H. Boehmer,et al. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice , 1991, Cell.
[46] S. Sakaguchi,et al. Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease , 1990, The Journal of experimental medicine.