Some desmoid tumors are characterized by trisomy 8

Ten desmoid tumors were examined by chromosome banding analysis and by in situ hybridization on short‐term cultures and frozen sections. Trisomy 8 was detected in four out of ten tumors, of which only one had shown trisomy 8 by karyotype analysis. Since trisomy 8 has been reported in superficial fibromatoses, which are clinically distinct but histologically similar to desmoid tumors, the occurrence of trisomy 8 in both may be a further indication of a close relationship. Genes Chromosom Cancer 10:131–135 (1994). © 1994 Wiley‐Liss, Inc.

[1]  D. Sheer,et al.  Diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumour based on the detection of t(11;22) using fluorescence in situ hybridisation. , 1993, British Journal of Cancer.

[2]  J. Delabie,et al.  Trisomy 7 and trisomy 10 characterize subpopulations of tumor-infiltrating lymphocytes in kidney tumors and in the surrounding kidney tissue. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[3]  A. Bonnici,et al.  Chromosomal Abnormalities in Dupuytren’s Contracture and Carpal Tunnel Syndrome , 1992, Journal of hand surgery.

[4]  J. Rowley,et al.  Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method. , 1992, Blood.

[5]  A. Sandberg,et al.  Clonal chromosomal abnormalities in desmoid tumors. Implications for histopathogenesis , 1992, Cancer.

[6]  F. Speleman,et al.  Analysis of whole-arm translocations in malignant blood cells by nonisotopic in situ hybridization. , 1991, Cytogenetics and cell genetics.

[7]  A. Raap,et al.  Interphase cytogenetics reveals somatic pairing of chromosome 17 centromeres in normal human brain tissue, but no trisomy 7 or sex-chromosome loss. , 1991, Cytogenetics and cell genetics.

[8]  D Pinkel,et al.  Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization , 1990, Science.

[9]  N. Archidiacono,et al.  A human alpha satellite DNA subset specific for chromosome 12. , 1990, American journal of human genetics.

[10]  S. H. Gibson,et al.  Cytogenetic studies in Dupuytren contracture. , 1988, American journal of human genetics.

[11]  F. Mitelman,et al.  Complex chromosome rearrangements in an extraabdominal desmoid tumor. , 1988, Cancer genetics and cytogenetics.

[12]  G. Wright,et al.  Chromosome abnormalities in Peyronie's disease. , 1987, The Journal of urology.

[13]  A. Sandberg,et al.  Application of long-term collagenase disaggregation for the cytogenetic analysis of human solid tumors. , 1986, Cancer genetics and cytogenetics.

[14]  Sergovich Fr,et al.  Nonrandom cytogenetic abnormalities in Dupuytren's disease. , 1983 .

[15]  D. Peakman,et al.  Prenatal diagnosis: techniques used to help in ruling out maternal cell contamination. , 1977, Journal of medical genetics.