Peptide-Based Materials That Exploit Metal Coordination

Metal–ion coordination has been widely exploited to control the supramolecular behavior of a variety of building blocks into functional materials. In particular, peptides offer great chemical diversity for metal-binding modes, combined with inherent biocompatibility and biodegradability that make them attractive especially for medicine, sensing, and environmental remediation. The focus of this review is the last 5 years’ progress in this exciting field to conclude with an overview of the future directions that this research area is currently undertaking.

[1]  S. Marchesan,et al.  Smart tools for antimicrobial peptides expression and application: The elastic perspective , 2022, Biotechnology and bioengineering.

[2]  C. Tedesco,et al.  Self-Assembly of Homo- and Hetero-Chiral Cyclodipeptides into Supramolecular Polymers towards Antimicrobial Gels , 2022, Polymers.

[3]  Sung Hyun Yoo,et al.  Crystalline Metal‐Peptide Networks: Structures, Applications, and Future Outlook , 2022, Chembiochem : a European journal of chemical biology.

[4]  S. Chasserot-Golaz,et al.  Development of Cu(ii)-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and importing bioavailable Cu into cells , 2022, Chemical science.

[5]  An Liu,et al.  Inhibition of Alzheimer's Aβ1‐42 Fibrillogenesis and Removal of Copper Ions by Polypeptides Modified Gold Nanoparticles , 2022, Chemistry & biodiversity.

[6]  Y. Uchida,et al.  Amino-Acid-Functionalized Metal–Organic Frameworks as Excellent Precursors toward Bifunctional Metal-Free Electrocatalysts , 2022, ACS Applied Energy Materials.

[7]  C. Palocci,et al.  Peptide-Based Hydrogels: New Materials for Biosensing and Biomedical Applications , 2022, Materials.

[8]  G. Rammes,et al.  Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly , 2022, Nature Communications.

[9]  Daniela Kalafatovic,et al.  Catalytic Peptides: the Challenge between Simplicity and Functionality , 2022, Israel Journal of Chemistry.

[10]  R. Jelinek,et al.  Catalytic amyloids , 2022, Trends in Chemistry.

[11]  Noor Aniza Harun,et al.  Overcoming Methicillin-Resistance Staphylococcus aureus (MRSA) Using Antimicrobial Peptides-Silver Nanoparticles , 2022, Antibiotics.

[12]  V. K. Rai,et al.  Metal nanoparticles against multi-drug-resistance bacteria. , 2022, Journal of inorganic biochemistry.

[13]  Asish Pal,et al.  Stimuli-Responsive Self-Assembly Disassembly in Peptide Amphiphiles to Endow Block-co-Fibers and Tunable Piezoelectric Response. , 2022, ACS applied materials & interfaces.

[14]  S. Marchesan,et al.  Self-Assembled Peptide Nanostructures for ECM Biomimicry , 2022, Nanomaterials.

[15]  S. Sadanandan,et al.  Recent Advances in Peptides-Based Stimuli-Responsive Materials for Biomedical and Therapeutic Applications: A Review. , 2022, Molecular pharmaceutics.

[16]  T. Keyes,et al.  Metal Peptide Conjugates in Cell and Tissue Imaging and Biosensing , 2022, Topics in Current Chemistry.

[17]  Antara Reja,et al.  Systems chemistry of peptide-assemblies for biochemical transformations. , 2022, Chemical Society reviews.

[18]  V. Pal,et al.  Cooperative Metal Ion Coordination to the Short Self-Assembling Peptide Promotes Hydrogelation and Cellular Proliferation. , 2022, Macromolecular bioscience.

[19]  C. Tonda-Turo,et al.  Antimicrobial peptide-based materials: opportunities and challenges. , 2022, Journal of materials chemistry. B.

[20]  U. Ruktanonchai,et al.  Antimicrobial Activity Enhancers: Towards Smart Delivery of Antimicrobial Agents , 2022, Antibiotics.

[21]  M. Schirone,et al.  Biogenic Amines in Meat and Meat Products: A Review of the Science and Future Perspectives , 2022, Foods.

[22]  A. Lavrentieva,et al.  Hybrid Nanoparticles and Composite Hydrogel Systems for Delivery of Peptide Antibiotics , 2022, International journal of molecular sciences.

[23]  Yuexing Zhang,et al.  Aspartic Acid-Assisted Size-Controllable Synthesis of Nanoscale Spherical Covalent Organic Frameworks with Chiral Interfaces for Inhibiting Amyloid-β Fibrillation. , 2022, ACS applied bio materials.

[24]  A. Merlino,et al.  Glucosyl Platinum(II) Complexes Inhibit Aggregation of the C-Terminal Region of the Aβ Peptide , 2022, Inorganic chemistry.

[25]  S. Marchesan,et al.  Polymer Conjugates of Antimicrobial Peptides (AMPs) with d-Amino Acids (d-aa): State of the Art and Future Opportunities , 2022, Pharmaceutics.

[26]  C. Toniolo,et al.  Peptide Self-Assembled Nanostructures: From Models to Therapeutic Peptides , 2022, Nanomaterials.

[27]  Wenjuan Wang,et al.  Supramolecular Self-Assembly of Atomically Precise Silver Nanoclusters with Chiral Peptide for Temperature Sensing and Detection of Arginine , 2022, Nanomaterials.

[28]  M. Tambuwala,et al.  Recent Advances in Metal-Based Antimicrobial Coatings for High-Touch Surfaces , 2022, International journal of molecular sciences.

[29]  R. Carpa,et al.  Inherent and Composite Hydrogels as Promising Materials to Limit Antimicrobial Resistance , 2022, Gels.

[30]  Ming-Rong Zhang,et al.  Peptide-based nanomaterials: Self-assembly, properties and applications , 2021, Bioactive materials.

[31]  Xuehai Yan,et al.  Supramolecular nanozymes based on peptide self-assembly for biomimetic catalysis , 2021, Nano Today.

[32]  L. Dong,et al.  Poly(l-cysteine) Peptide Amphiphile Derivatives Containing Disulfide Bonds: Synthesis, Self-Assembly-Induced β-Sheet Nanostructures, pH/Reduction Dual Response, and Drug Release. , 2021, Biomacromolecules.

[33]  D. Marasco,et al.  Self-Assembling Peptides: From Design to Biomedical Applications , 2021, International Journal of Molecular Sciences.

[34]  Andrzej S. Skwarecki,et al.  Amino Acid Based Antimicrobial Agents – Synthesis and Properties , 2021, ChemMedChem.

[35]  P. Fornasiero,et al.  Nanostructured Ceria: Biomolecular Templates and (Bio)applications , 2021, Nanomaterials.

[36]  R. Bjornsson,et al.  Synthesis, Characterization, and Reaction Studies of Pd(II) Tripeptide Complexes , 2021, Molecules.

[37]  Cai-Ping Tan,et al.  Inhibition of Aβ peptide aggregation by ruthenium(II) polypyridyl complexes through copper chelation. , 2021, Journal of inorganic biochemistry.

[38]  M. Barz,et al.  Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium(II) complexes. , 2021, Journal of materials chemistry. B.

[39]  R. Kapsa,et al.  Enhancing Peptide Biomaterials for Biofabrication , 2021, Polymers.

[40]  Patrick Severin Sfragano,et al.  The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics , 2021, Biosensors.

[41]  Simone Adorinni,et al.  Cages meet gels: Smart materials with dual porosity , 2021, Matter.

[42]  M. Mba,et al.  Metal Cation Triggered Peptide Hydrogels and Their Application in Food Freshness Monitoring and Dye Adsorption , 2021, Gels.

[43]  Noelia Maldonado,et al.  Advances and Novel Perspectives on Colloids, Hydrogels, and Aerogels Based on Coordination Bonds with Biological Interest Ligands , 2021, Nanomaterials.

[44]  J. Skopińska-Wiśniewska,et al.  From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances , 2021, International journal of molecular sciences.

[45]  C. Charitidis,et al.  Self-Assembling Peptides and Carbon Nanomaterials Join Forces for Innovative Biomedical Applications , 2021, Molecules.

[46]  Huiling Gao,et al.  A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu2+-Mediated Aβ Aggregation , 2021, International journal of molecular sciences.

[47]  James J. Choi,et al.  Modulation of amyloid-β aggregation by metal complexes with a dual binding mode and their delivery across the blood–brain barrier using focused ultrasound† , 2021, Chemical science.

[48]  Zhimou Yang,et al.  Peptide-based supramolecular hydrogels for local drug delivery. , 2021, Advanced drug delivery reviews.

[49]  A. Whitworth,et al.  Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives. , 2021, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

[50]  J. Rudra,et al.  Peptide-based supramolecular vaccine systems , 2021, Acta biomaterialia.

[51]  Hao Wang,et al.  Chemical Reactions Trigger Peptide Self‐Assembly in vivo for Tumor Therapy , 2021, ChemMedChem.

[52]  R. Maier,et al.  The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation , 2021, Scientific Reports.

[53]  Xiaoyun Dai,et al.  A Cyclic Dipeptide from Marine Fungus Penicillium chrysogenum DXY-1 Exhibits Anti-quorum Sensing Activity , 2021, ACS omega.

[54]  I. Iacobucci,et al.  A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications , 2021, International journal of molecular sciences.

[55]  A. Romanelli,et al.  Morpholino-based peptide oligomers: Synthesis and DNA binding properties. , 2021, Biochemical and biophysical research communications.

[56]  K. Várnagy,et al.  Recent Multi-Target Approaches on the Development of Anti-Alzheimer`s Agents Integrating Metal Chelation Activity. , 2021, Current medicinal chemistry.

[57]  A. Vargiu,et al.  Nanoscale Assembly of Functional Peptides with Divergent Programming Elements , 2021, ACS nano.

[58]  M. Guler,et al.  Electroactive peptide-based supramolecular polymers , 2021, Materials today. Bio.

[59]  M. Buehler,et al.  Transition-metal coordinate bonds for bioinspired macromolecules with tunable mechanical properties , 2021, Nature Reviews Materials.

[60]  S. Dey,et al.  Metal Coordinated Supramolecular Polymers from the Minimalistic Hybrid Peptide Foldamers. , 2021, Angewandte Chemie.

[61]  Ajay Kumar,et al.  Amino Acid-Functionalized Metal-Organic Frameworks for Asymmetric Base-Metal Catalysis. , 2021, Angewandte Chemie.

[62]  M. C. Cringoli,et al.  Peptide Gelators to Template Inorganic Nanoparticle Formation , 2021, Gels.

[63]  G. Morelli,et al.  Peptide‐based hydrogels as delivery systems for doxorubicin , 2021, Journal of peptide science : an official publication of the European Peptide Society.

[64]  Peng Yang,et al.  Metal-Protein Hybrid Materials with Desired Functions and Potential Applications. , 2021, ACS applied bio materials.

[65]  Miguel A. Soler,et al.  Computational Evolution of Beta-2-Microglobulin Binding Peptides for Nanopatterned Surface Sensors , 2021, International journal of molecular sciences.

[66]  Sai Bi,et al.  Recent advances in templated synthesis of metal nanoclusters and their applications in biosensing, bioimaging and theranostics. , 2020, Biosensors & bioelectronics.

[67]  R. Carlos,et al.  Comparison of Aβ (1-40, 1-28, 11-22, and 29-40) aggregation processes and inhibition of toxic species generated in early stages of aggregation by a water-soluble ruthenium complex. , 2020, Journal of inorganic biochemistry.

[68]  T. Waigh,et al.  Electronics of peptide- and protein-based biomaterials. , 2020, Advances in colloid and interface science.

[69]  I. Hamley,et al.  Peptide-Based Gel in Environmental Remediation: Removal of Toxic Organic Dyes and Hazardous Pb2+ and Cd2+ Ions from Wastewater and Oil Spill Recovery. , 2020, Langmuir : the ACS journal of surfaces and colloids.

[70]  Scott J. Miller,et al.  Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms. , 2020, Chemical reviews.

[71]  C. Hu,et al.  Mechanistic insights of evaporation-induced actuation in supramolecular crystals , 2020, Nature Materials.

[72]  Yong-Xiang Chen,et al.  Metal ion and light sequentially induced sol-gel-sol transition of a responsive peptide-hydrogel. , 2020, Soft matter.

[73]  C. Diaferia,et al.  Systematic overview of soft materials as a novel frontier for MRI contrast agents , 2020, RSC advances.

[74]  Hong‐Cai Zhou,et al.  Engineering a homochiral metal-organic framework based on an amino acid for enantioselective separation. , 2020, Chemical communications.

[75]  N. Zhang,et al.  Transition metal complexes constructed by pyridine–amino acid: fluorescence sensing and catalytic properties , 2020, Transition Metal Chemistry.

[76]  A. Cherif,et al.  Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (l-leu-l-pro) from Streptomyces misionensis V16R3Y1 Bacteria Extracts. A Novel 1H NMR Metabolomic Approach , 2020, Antibiotics.

[77]  Jian-Zhi Wang,et al.  Current understanding of metal ions in the pathogenesis of Alzheimer’s disease , 2020, Translational Neurodegeneration.

[78]  John B. Matson,et al.  H2S-releasing amphiphilic dipeptide hydrogels are potent S. aureus biofilm disruptors. , 2020, Biomaterials science.

[79]  Kelly M. Schultz,et al.  Nine-residue peptide self-assembles in the presence of silver to produce a self-healing, cytocompatible, antimicrobial hydrogel. , 2020, ACS applied materials & interfaces.

[80]  Yan Sun,et al.  Conjugation of RTHLVFFARK to human lysozyme creates a potent multifunctional modulator for Cu2+-mediated amyloid β-protein aggregation and cytotoxicity. , 2020, Journal of materials chemistry. B.

[81]  Can Wu,et al.  Double-Crosslinked Nanocomposite Hydrogels for Temporal Control of Drug Dosing in Combination Therapy. , 2020, Acta biomaterialia.

[82]  E. Gazit,et al.  Biocompatible Hybrid Organic/Inorganic Micro-Hydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo. , 2020, Nano letters.

[83]  T. Jiao,et al.  Multifunctional Antimicrobial Biometallohydrogels Based on Amino Acid Coordinated Self-Assembly. , 2020, Small.

[84]  P. Thordarson,et al.  Beyond Fmoc: a review of aromatic peptide capping groups. , 2020, Journal of materials chemistry. B.

[85]  H. Kraatz,et al.  Supramolecular Peptide Gels: Influencing Properties by Metal Ion Coordination and Their Wide-Ranging Applications , 2020, ACS omega.

[86]  H. Lee,et al.  Iron Ion-Releasing Polypeptide Thermogel for Neuronal Differentiation of Mesenchymal Stem Cells. , 2020, Biomacromolecules.

[87]  M. C. Cringoli,et al.  Self-assembly of an amino acid derivative into an antimicrobial hydrogel biomaterial. , 2019, Chemistry.

[88]  Chi Wu,et al.  Temperature-driven Metalloprotein-based Hybrid Hydrogels for Selective and Reversible Removal of Cadmium(II) from Water. , 2019, ACS applied materials & interfaces.

[89]  Y. Lim,et al.  Self-Assembling Peptides and Their Application in the Treatment of Diseases , 2019, International journal of molecular sciences.

[90]  Huiling Gao,et al.  Screening a specific Zn(ii)-binding peptide for improving the cognitive decline of Alzheimer's disease in APP/PS1 transgenic mice by inhibiting Zn2+-mediated amyloid protein aggregation and neurotoxicity. , 2019, Biomaterials science.

[91]  Fan Huang,et al.  Self-assembling peptide-based nanodrug delivery systems. , 2019, Biomaterials science.

[92]  Leixia Mei,et al.  Co-assembled supramolecular hydrogels of cell adhesive peptide and alginate for rapid hemostasis and efficacious wound healing. , 2019, Soft matter.

[93]  K. Lam,et al.  Peptide-based materials for cancer immunotherapy , 2019, Theranostics.

[94]  T. Meade,et al.  Inhibition of Amyloid-β Aggregation by Cobalt(III) Schiff Base Complexes: A Computational and Experimental Approach. , 2019, Journal of the American Chemical Society.

[95]  A. Shamloo,et al.  Identification of a novel multifunctional ligand for simultaneous inhibition of Amyloid-Beta (Aβ42) and chelation of zinc metal ion. , 2019, ACS chemical neuroscience.

[96]  Mark Platt,et al.  Peptide Nanocarriers for the Detection of Heavy Metal Ions Using Resistive Pulse Sensing. , 2019, Analytical chemistry.

[97]  H. Kaur,et al.  Inducing Differential Self-Assembling Behavior in Ultrashort Peptide Hydrogelators Using Simple Metal Salts. , 2019, Biomacromolecules.

[98]  E. Gazit,et al.  Metal-Ion Modulated Structural Transformation of Amyloid-Like Dipeptide Supramolecular Self-Assembly. , 2019, ACS nano.

[99]  Yi Cao,et al.  A Highly Stretchable, Tough, Fast Self-Healing Hydrogel Based on Peptide–Metal Ion Coordination , 2019, Biomimetics.

[100]  S. Kralj,et al.  Embedding and Positioning of Two Fe II 4 L 4 Cages in Supramolecular Tripeptide Gels for Selective Chemical Segregation , 2019, Angewandte Chemie.

[101]  S. Kralj,et al.  Embedding and Positioning of Two FeII 4L4 Cages in Supramolecular Tripeptide Gels for Selective Chemical Segregation , 2019, Angewandte Chemie.

[102]  C. Diaferia,et al.  Peptide‐based building blocks as structural elements for supramolecular Gd‐containing MRI contrast agents , 2019, Journal of peptide science : an official publication of the European Peptide Society.

[103]  Lixin Wu,et al.  Coassembly of Short Peptide and Polyoxometalate into Complex Coacervate Adapted for pH and Metal Ion-Triggered Underwater Adhesion. , 2019, Langmuir : the ACS journal of surfaces and colloids.

[104]  K. Blank,et al.  Bioinspired Histidine–Zn2+ Coordination for Tuning the Mechanical Properties of Self-Healing Coiled Coil Cross-Linked Hydrogels , 2019, Biomimetics.

[105]  G. Morelli,et al.  Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems , 2019, International journal of molecular sciences.

[106]  S. Bhattacharya,et al.  Perfluoroarene induces a pentapeptidic hydrotrope into a pH-tolerant hydrogel allowing naked eye sensing of Ca2+ ions. , 2019, Nanoscale.

[107]  Xiaoyan Dong,et al.  d-Enantiomeric RTHLVFFARK-NH2: A Potent Multifunctional Decapeptide Inhibiting Cu2+-Mediated Amyloid β-Protein Aggregation and Remodeling Cu2+-Mediated Amyloid β Aggregates. , 2019, ACS chemical neuroscience.

[108]  U. Kortz,et al.  Polyoxometalates in Biomedicine: Update and Overview. , 2019, Current medicinal chemistry.

[109]  L. D'Andrea,et al.  Pro-angiogenic peptides in biomedicine. , 2018, Archives of biochemistry and biophysics.

[110]  Lei Wang,et al.  Programmable Construction of Peptide‐Based Materials in Living Subjects: From Modular Design and Morphological Control to Theranostics , 2018, Advanced materials.

[111]  A. Amanzadi,et al.  Designing a new multifunctional peptide for metal chelation and Aβ inhibition. , 2018, Archives of biochemistry and biophysics.

[112]  Yan Sun,et al.  Carnosine-LVFFARK-NH2 Conjugate: A Moderate Chelator but Potent Inhibitor of Cu2+-Mediated Amyloid β-Protein Aggregation. , 2018, ACS chemical neuroscience.

[113]  H. Kraatz,et al.  Supramolecular Assembly of Peptide and Metallopeptide Gelators and Their Stimuli-Responsive Properties in Biomedical Applications. , 2018, Chemistry.

[114]  S. Rudaz,et al.  Facile Synthesis, Size-Separation, Characterization, and Antimicrobial Properties of Thiolated Copper Clusters , 2018, ACS Applied Nano Materials.

[115]  U. Sonavane,et al.  Acetylcholinesterase and Aβ Aggregation Inhibition by Heterometallic Ruthenium(II)-Platinum(II) Polypyridyl Complexes. , 2018, Inorganic chemistry.

[116]  Jie Zheng,et al.  Design of nonapeptide LVFFARKHH: A bifunctional agent against Cu2+‐mediated amyloid β‐protein aggregation and cytotoxicity , 2018, Journal of molecular recognition : JMR.

[117]  Yan Sun,et al.  RTHLVFFARK-NH2: A potent and selective modulator on Cu2+-mediated amyloid-β protein aggregation and cytotoxicity. , 2018, Journal of inorganic biochemistry.

[118]  K. Sharma,et al.  Short Antimicrobial Peptides. , 2018, Recent patents on anti-infective drug discovery.

[119]  Chan Beum Park,et al.  Light-triggered dissociation of self-assembled β-amyloid aggregates into small, nontoxic fragments by ruthenium (II) complex. , 2017, Acta biomaterialia.

[120]  C. Becker,et al.  Recent Advances in Peptide-Based Approaches for Cancer Treatment. , 2020, Current medicinal chemistry.

[121]  P. Thordarson,et al.  Tuning hydrogels through metal-based gelation triggers. , 2017, Journal of materials chemistry. B.

[122]  I. Hamley,et al.  Peptide-based ambidextrous bifunctional gelator: applications in oil spill recovery and removal of toxic organic dyes for waste water management , 2017, Interface Focus.

[123]  Wei Wang,et al.  Printable Fluorescent Hydrogels Based on Self-Assembling Peptides , 2017, Scientific Reports.

[124]  Peijun Zhang,et al.  Peptide-Directed Assembly of Single-Helical Gold Nanoparticle Superstructures Exhibiting Intense Chiroptical Activity. , 2016, Journal of the American Chemical Society.

[125]  L. Adler-Abramovich,et al.  Fmoc-modified amino acids and short peptides: simple bio-inspired building blocks for the fabrication of functional materials. , 2016, Chemical Society reviews.

[126]  Y. Tan,et al.  Rational Design of Biomolecular Templates for Synthesizing Multifunctional Noble Metal Nanoclusters toward Personalized Theranostic Applications , 2016, Advanced healthcare materials.

[127]  H. Tian,et al.  Peptide self-assembly triggered by metal ions. , 2015, Chemical Society reviews.

[128]  V. Perugini,et al.  Silver-doped self-assembling di-phenylalanine hydrogels as wound dressing biomaterials , 2013, Journal of Materials Science: Materials in Medicine.

[129]  I. Sóvágó,et al.  Peptides as complexing agents: Factors influencing the structure and thermodynamic stability of peptide complexes , 2012 .

[130]  Meital Reches,et al.  Casting Metal Nanowires Within Discrete Self-Assembled Peptide Nanotubes , 2003, Science.

[131]  Claudio Soto,et al.  β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy , 1998, Nature Medicine.

[132]  H. Vahrenkamp,et al.  Zinc Complexes of Histidine‐Containing Di‐ and Tripeptides , 1995 .

[133]  H. Johnson,et al.  A comparison of 'traditional' and multimedia information systems development practices , 2003, Inf. Softw. Technol..