Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets

[1]  A. Nishizono,et al.  Suppression of the Bacterial Antigen‐Specific T Cell Response and the Dendritic Cell Migration to the Lymph Nodes by Osteopontin , 2007, Microbiology and immunology.

[2]  M. Idzko,et al.  Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. , 2006, The Journal of clinical investigation.

[3]  R. Schreiber,et al.  Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation1 , 2006, The Journal of Immunology.

[4]  N. Lukacs,et al.  Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus , 2006, The Journal of experimental medicine.

[5]  F. Tacke,et al.  Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts , 2006, Nature Immunology.

[6]  John D Lambris,et al.  A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. , 2006, The Journal of clinical investigation.

[7]  R. Coffman,et al.  Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction , 2005, The Journal of experimental medicine.

[8]  L. Glimcher,et al.  T-bet-dependent expression of osteopontin contributes to T cell polarization. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[9]  P. Allavena,et al.  Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different. , 2005, Blood.

[10]  T. Ahrens,et al.  Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype. , 2005, Blood.

[11]  S. Haeryfar.  The importance of being a pDC in antiviral immunity: the IFN mission versus Ag presentation? , 2005, Trends in immunology.

[12]  J. Schroeder,et al.  Level of osteopontin is increased after bee venom immunotherapy. , 2005, The Journal of allergy and clinical immunology.

[13]  Sarah J. McMillan,et al.  Manipulation of Allergen-Induced Airway Remodeling by Treatment with Anti-TGF-β Antibody: Effect on the Smad Signaling Pathway1 , 2005, The Journal of Immunology.

[14]  H. Nie,et al.  Role of osteopontin in amplification and perpetuation of rheumatoid synovitis. , 2005, The Journal of clinical investigation.

[15]  M. Willart,et al.  In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma , 2005, The Journal of experimental medicine.

[16]  R. Ravazzolo,et al.  Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus. , 2005, Arthritis and rheumatism.

[17]  Simon C Watkins,et al.  Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance1 , 2005, The Journal of Immunology.

[18]  M. Suga,et al.  Differentiation, Maturation, and Survival of Dendritic Cells by Osteopontin Regulation , 2005, Clinical Diagnostic Laboratory Immunology.

[19]  H. Hammad,et al.  Dendritic cells in the pathogenesis of asthma , 2004 .

[20]  G. Berry,et al.  Induction of T helper type 1–like regulatory cells that express Foxp3 and protect against airway hyper-reactivity , 2004, Nature Immunology.

[21]  S. Orkin,et al.  A Critical Role for Eosinophils in Allergic Airways Remodeling , 2004, Science.

[22]  F. Lund-Johansen,et al.  Plasmacytoid dendritic cells activate allergen-specific TH2 memory cells: modulation by CpG oligodeoxynucleotides. , 2004, The Journal of allergy and clinical immunology.

[23]  H. Hammad,et al.  Essential Role of Lung Plasmacytoid Dendritic Cells in Preventing Asthmatic Reactions to Harmless Inhaled Antigen , 2004, The Journal of experimental medicine.

[24]  D. Liggitt,et al.  Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells , 2004, Nature Immunology.

[25]  G. Trinchieri,et al.  Mouse Strain Differences in Plasmacytoid Dendritic Cell Frequency and Function Revealed by a Novel Monoclonal Antibody , 2003, The Journal of Immunology.

[26]  H. Hammad,et al.  Taking our breath away: dendritic cells in the pathogenesis of asthma , 2003, Nature Reviews Immunology.

[27]  H. Groux,et al.  Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. , 2003, Immunity.

[28]  R. Pedotti,et al.  Response to Comment on "The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease" , 2003, Science.

[29]  S. Kikuchi,et al.  Genetic polymorphisms of osteopontin in association with multiple sclerosis in Japanese patients , 2003, Journal of Neuroimmunology.

[30]  A. Liu.  Early intervention for asthma prevention in children. , 2002, Allergy and asthma proceedings.

[31]  L. Klein,et al.  Cutting Edge: Attenuated Experimental Autoimmune Encephalomyelitis in Eta-1/Osteopontin-Deficient Mice1 , 2002, The Journal of Immunology.

[32]  A. McKenzie,et al.  The Absence of Interleukin 9 Does Not Affect the Development of Allergen-induced Pulmonary Inflammation nor Airway Hyperreactivity , 2002, The Journal of experimental medicine.

[33]  F. Autschbach,et al.  Expression of Osteopontin (Eta-1) in Crohn Disease of the Terminal Ileum , 2002, Scandinavian journal of gastroenterology.

[34]  T. Ahrens,et al.  Osteopontin Is Involved in the Initiation of Cutaneous Contact Hypersensitivity by Inducing Langerhans and Dendritic Cell Migration to Lymph Nodes , 2001, The Journal of experimental medicine.

[35]  M. Gunn,et al.  Cd11c+B220+Gr-1+ Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells , 2001, The Journal of experimental medicine.

[36]  F. Granucci,et al.  Analysis of the relationship between viral infection and autoimmune disease. , 2001, Immunity.

[37]  N. Kajiwara,et al.  Interleukin 12 P40 Production by Barrier Epithelial Cells during Airway Inflammation , 2001, The Journal of experimental medicine.

[38]  R. Pauwels,et al.  Specific Migratory Dendritic Cells Rapidly Transport Antigen from the Airways to the Thoracic Lymph Nodes , 2001, The Journal of experimental medicine.

[39]  P. Bongrand,et al.  Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma. Increased IFN-gamma-producing CD8(+) T cells in asthma. , 2000, American journal of respiratory and critical care medicine.

[40]  Gaga,et al.  Eosinophils are a feature of upper and lower airway pathology in non‐atopic asthma, irrespective of the presence of rhinitis , 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[41]  M. Glimcher,et al.  Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. , 2000, Science.

[42]  G. Berry,et al.  Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. , 1999, The Journal of clinical investigation.

[43]  H. Cantor,et al.  The immunology of Eta-1/osteopontin. , 1996, Cytokine & growth factor reviews.

[44]  M. Clerici,et al.  Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases , 1996, Clinical microbiology reviews.

[45]  P. Howarth,et al.  T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. , 1996, American journal of respiratory cell and molecular biology.

[46]  F. Finkelman,et al.  Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice , 1995, The Journal of experimental medicine.

[47]  F. Blattner,et al.  Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection , 1989, The Journal of experimental medicine.

[48]  R. Coffman,et al.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.

[49]  S. Youssef,et al.  Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells , 2007, Nature Immunology.

[50]  L. Glimcher,et al.  Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. , 2006, Nature immunology.

[51]  Sarah J. McMillan,et al.  PathwayAntibody: Effect on the Smad Signaling b Remodeling by Treatment with Anti-TGF-Manipulation of Allergen-Induced Airway , 2005 .

[52]  H. Cantor,et al.  Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene. , 1993, Critical reviews in immunology.