DNA–magnetite nanocomposite materials

It is shown here that magnetite nanoparticles can be associated with double-stranded DNA. In a first step, a complex of DNA with Fe 2q and Fe 3q ions is formed. qThen, in a second step, magnetite nanoparticles are formed by increasing the pH. As shown by electrophoresis, the nanoparticles are strongly attached to the nucleic acid. From TEM imaging and Mossbauer measurement, a tentative model for the textural organization of DNA and magnetite is proposed. q 2000 Elsevier ¨