[Juvenile idiopathic arthritis and uveitis: epidemiology including data from a national database].

Uveitis is a potentially vision-threatening extra-articular manifestation of juvenile idiopathic arthritis (JIA) that manifests in approximately 13 % of all patients. According to the national ophthalmological and paediatric rheumatological database, one out of four children with JIA and uveitis develops ocular complications such as synechiae, band keratopathy, cataract, glaucoma and macula oedema. Independent risk factors of uveitis include the presence of a certain JIA subgroup, of antinuclear antibodies and age at onset. A late diagnosis, however, seems to be the relevant risk factor for uveitis complications in the course of the disease. The diagnosis of uveitis as early as possible is therefore the most important factor for a reduction of the morbidity of uveitis. Due to the usual lack of symptoms the diagnosis of uveitis requires, however, an examination by an ophthalmologist. This should be done immediately after the diagnosis of JIA and repeated in a risk-adapted manner during the follow-up.

[1]  E. Zeggini,et al.  Association of HLA-DRB1*13 with susceptibility to uveitis in juvenile idiopathic arthritis in two independent data sets. , 2006, Rheumatology.

[2]  J. Kivlin,et al.  Ophthalmologic Examinations in Children With Juvenile Rheumatoid Arthritis , 2006, Pediatrics.

[3]  S. Cha,et al.  Incidence and outcomes of uveitis in juvenile rheumatoid arthritis, a synthesis of the literature , 2006, Graefe's Archive for Clinical and Experimental Ophthalmology.

[4]  U. Pleyer,et al.  Epidemiologische Daten zur Uveitis bei juveniler idiopathischer Arthritis aus einer bundesweiten pädiatrischen und ophthalmologischen Datenerhebung (Uveitis-Modul der Kerndokumentation) , 2005 .

[5]  Douglas A Jabs,et al.  Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. , 2005, American journal of ophthalmology.

[6]  M. Leirisalo-Repo,et al.  Uveitis in young adults with juvenile idiopathic arthritis: a clinical evaluation of 123 patients , 2005, Annals of the rheumatic diseases.

[7]  M. Suarez‐Almazor,et al.  International League of Associations for Rheumatology: International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001 , 2004 .

[8]  J. Vela,et al.  [Anterior uveitis and juvenile idiopathic arthritis]. , 2003, Archivos de la Sociedad Espanola de Oftalmologia.

[9]  K. Aho,et al.  Recent advances in uveitis of juvenile idiopathic arthritis. , 2003, Survey of ophthalmology.

[10]  M. Marinò,et al.  Prognosis of Juvenile Rheumatoid Arthritis-Associated Uveitis , 2003, European journal of ophthalmology.

[11]  C. Edelsten,et al.  Factors related to severe uveitis at diagnosis in children with juvenile idiopathic arthritis in a screening program. , 2003, American journal of ophthalmology.

[12]  N. Ilowite,et al.  Time of onset of uveitis in children with juvenile rheumatoid arthritis. , 2002, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus.

[13]  V. Gerloni,et al.  Early predictors of severe course of uveitis in oligoarticular juvenile idiopathic arthritis. , 2002, The Journal of rheumatology.

[14]  K. Minden,et al.  Long-term outcome in patients with juvenile idiopathic arthritis. , 2002, Arthritis and rheumatism.

[15]  P. Manners,et al.  Worldwide prevalence of juvenile arthritis why does it vary so much? , 2002, The Journal of rheumatology.

[16]  J. Kanski,et al.  An evaluation of baseline risk factors predicting severity in juvenile idiopathic arthritis associated uveitis and other chronic anterior uveitis in early childhood , 2002, The British journal of ophthalmology.

[17]  H. Kautiainen,et al.  Occurrence of uveitis in recently diagnosed juvenile chronic arthritis: a prospective study. , 2001, Ophthalmology.

[18]  T. Southwood,et al.  Juvenile idiopathic arthritis and uveitis: the classification conundrum , 2000, Eye.

[19]  C. Rosé,et al.  Prevalence and outcome of uveitis in a regional cohort of patients with juvenile rheumatoid arthritis. , 1997, The Journal of rheumatology.

[20]  O. Blegvad IRIDOCYCLITIS AND DISEASE OF THE JOINTS IN CHILDREN , 1941 .

[21]  Andrew D. Dick,et al.  The standardization of uveitis nomenclature (SUN) working group; standardization of uveitis nomenclature for reporting clinical data: Results of the first international workshop , 2005 .

[22]  B. Andersson Gäre,et al.  Incidence of juvenile idiopathic arthritis in the Nordic countries. A population based study with special reference to the validity of the ILAR and EULAR criteria. , 2003, The Journal of rheumatology.

[23]  A. Fasth,et al.  A prospective population based study on outcome of juvenile chronic arthritis in Costa Rica. , 2002, The Journal of rheumatology.