[123I]-β-CIT SPECT Imaging Shows Reduced Thalamus–Hypothalamus Serotonin Transporter Availability in 24 Drug-Free Obsessive-Compulsive Checkers

[1]  Marco Leyton,et al.  Lack of Effects on Core Obsessive-Compulsive Symptoms of Tryptophan Depletion During Symptom Provocation in Remitted Obsessive-Compulsive Disorder Patients , 2006, Biological Psychiatry.

[2]  E. Storch,et al.  Clinical predictors of early fluoxetine treatment response in obsessive–compulsive disorder , 2006, Depression and anxiety.

[3]  Y. Reddy,et al.  Clinical predictors of drug nonresponse in obsessive-compulsive disorder. , 2005, The Journal of clinical psychiatry.

[4]  C. Halldin,et al.  Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2 , 2005, European Neuropsychopharmacology.

[5]  I. Podreka,et al.  β-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo , 2005, Journal of Neural Transmission / General Section JNT.

[6]  J. Kornhuber,et al.  SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain , 2005, Journal of Neural Transmission / General Section JNT.

[7]  N. V. D. Van der Wee,et al.  Enhanced dopamine transporter density in psychotropic-naive patients with obsessive-compulsive disorder shown by [123I]{beta}-CIT SPECT. , 2004, The American journal of psychiatry.

[8]  U. Müller,et al.  Reduced serotonin transporter–availability in obsessive–compulsive disorder (OCD) , 2004, European Archives of Psychiatry and Clinical Neuroscience.

[9]  Esko Vanninen,et al.  Initial experience with single-photon emission tomography using iodine-123-labelled 2 β-carbomethoxy-3β-(4-iodophenyl)tropane in human brain , 1993, European Journal of Nuclear Medicine.

[10]  E. Hollander,et al.  Serotonin-1D hypothesis of obsessive-compulsive disorder: an update. , 2004, The Journal of clinical psychiatry.

[11]  H. Möller,et al.  Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder , 2003, Biological Psychiatry.

[12]  Mark Slifstein,et al.  Serotonin transporters in obsessive-compulsive disorder: a positron emission tomography study with [11C]McN 5652 , 2003, Biological Psychiatry.

[13]  S. Kasper,et al.  [123I] β-CIT and single photon emission computed tomography reveal reduced brain serotonin transporter availability in bulimia nervosa , 2001, Biological Psychiatry.

[14]  S. Rauch,et al.  Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. , 2000, The Psychiatric clinics of North America.

[15]  J. Seibyl,et al.  Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients. , 2000, The American journal of psychiatry.

[16]  Alexander Neumeister,et al.  [123I]-β-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder , 2000, Biological Psychiatry.

[17]  J Tauscher,et al.  Imaging serotonin and dopamine transporters with 123I-beta-CIT SPECT: binding kinetics and effects of normal aging. , 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[18]  S. Rauch,et al.  Use of factor-analyzed symptom dimensions to predict outcome with serotonin reuptake inhibitors and placebo in the treatment of obsessive-compulsive disorder. , 1999, The American journal of psychiatry.

[19]  Linda Carpenter,et al.  Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography , 1998, Biological Psychiatry.

[20]  R Coppola,et al.  Reduced central serotonin transporters in alcoholism. , 1998, The American journal of psychiatry.

[21]  Andreas Heinz,et al.  Tourette's syndrome , 1998, Neurology.

[22]  A L Brody,et al.  Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder , 1998, British Journal of Psychiatry.

[23]  H. Baumgarten,et al.  Role of serotonin in obsessive-compulsive disorder , 1998, British Journal of Psychiatry.

[24]  E. Hollander,et al.  SSRIs in the Treatment of obsessive‐compulsive disorder , 1998, Depression and anxiety.

[25]  P. Hof,et al.  [3H]Nisoxetine binding sites in the cat brain: An autoradiographic study , 1995, Neuroscience.

[26]  Robert B. Innis,et al.  Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[27]  C. McDougle,et al.  Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors. , 1994, Archives of general psychiatry.

[28]  D. Mash,et al.  Visualizing Dopamine and Serotonin Transporters in the Human Brain with the Potent Cocaine Analogue [125I]RTI‐55: In Vitro Binding and Autoradiographic Characterization , 1994, Journal of neurochemistry.

[29]  C. Halldin,et al.  Pet study of [11C] β‐CIT binding to monoamine transporters in the monkey and human brain , 1994, Synapse.

[30]  Suck-Won Kim,et al.  The Yale-Brown Obsessive-Compulsive Scale: Measures of internal consistency , 1994, Psychiatry Research.

[31]  Marc Laruelle,et al.  SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates , 1993, Synapse.

[32]  E. John,et al.  Quantitative electroencephalographic subtyping of obsessive-compulsive disorder , 1993, Psychiatry Research: Neuroimaging.

[33]  T. Insel,et al.  Toward a neuroanatomy of obsessive-compulsive disorder. , 1992, Archives of general psychiatry.

[34]  F I Carroll,et al.  High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brain , 1992, Synapse.

[35]  C. McDougle,et al.  The role of serotonin and dopamine in the pathophysiology of obsessive compulsive disorder , 1992, International clinical psychopharmacology.

[36]  S. Tejani-butt.  [3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. , 1992, The Journal of pharmacology and experimental therapeutics.

[37]  E. Hollander,et al.  Serotonergic function in obsessive-compulsive disorder. Behavioral and neuroendocrine responses to oral m-chlorophenylpiperazine and fenfluramine in patients and healthy volunteers. , 1992, Archives of general psychiatry.

[38]  P B Hoffer,et al.  [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain. , 1991, Journal of medicinal chemistry.

[39]  M Laruelle,et al.  Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT. , 1991, European journal of pharmacology.

[40]  J. Krystal,et al.  Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. , 1990, Archives of general psychiatry.

[41]  M. Torrens.  Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268 , 1990 .

[42]  W. Goodman,et al.  The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. , 1989, Archives of general psychiatry.

[43]  W. Goodman,et al.  The Yale-Brown Obsessive Compulsive Scale. II. Validity. , 1989, Archives of general psychiatry.

[44]  G. Vauquelin,et al.  [3H]GBR 12935 Binding to Dopamine Uptake Sites in the Human Brain , 1989, Journal of neurochemistry.

[45]  J. Marcusson,et al.  High affinity [3H]paroxetine binding to serotonin uptake sites in human brain tissue , 1989, Brain Research.

[46]  T. Insel,et al.  Serotonergic responsivity in obsessive-compulsive disorder. Effects of chronic clomipramine treatment. , 1988, Archives of general psychiatry.

[47]  J. Rapoport,et al.  Treatment of childhood obsessive compulsive disorder with clomipramine and desmethylimipramine: a double-blind crossover comparison. , 1988, Psychopharmacology bulletin.

[48]  T. Insel,et al.  Serotonergic responsivity in obsessive-compulsive disorder. Comparison of patients and healthy controls. , 1987, Archives of general psychiatry.

[49]  M. Mintun,et al.  A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography , 1984, Annals of neurology.

[50]  M. Hamilton.  A RATING SCALE FOR DEPRESSION , 1960, Journal of neurology, neurosurgery, and psychiatry.