Elimination of Central Artefacts of L-SPECT with Modular Partial Ring Detectors by Shifting Center of Scanning

The Lightfield Single Photon Emission Computed Tomography (L-SPECT) system is developed to overcome some of the drawbacks in conventional SPECT by applying the idea of plenoptic imaging. This system displayed improved performance in terms of reduced information loss and scanning time when compared to the SPECT system which has a conventional collimator. The SPECT system is transformed into L-SPECT system by replacing the conventional collimators with micro-range multi-pinhole arrays. The field of view (FOV) of the L-SPECT system is enhanced by reshaping the detector head into ring-type by tiling small detector modules. The L-SPECT system with modular partial ring detectors (MPRD L-SPECT) exhibits cylindrical artefacts during volumetric reconstruction. Hence, here the work is focused to remove the cylindrical artefacts in the reconstruction of the examined objects by changing the scanning orbit. The enhancement is done such that the center of scanning of the L-SPECT system with MPRD L-SPECT is shifted at different values. The reconstruction quality of MPRD L-SPECT with and without center shifting is evaluated in terms of the Full Width at Half Maximum (FWHM) and Modulation Transfer Function (MTF). Moreover, the visual comparison is also examined. The results indicate that center shifting of MPRD L-SPECT overcomes the problem of the central artefact with improved FWHM. By increasing MPRD's scanning center shift gap, the spatial resolution can be further improved.

[1]  Kisung Lee,et al.  A miniature SPECT using multi-pinhole collimator with vertical septa , 2009, 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC).

[2]  R. Siddon Fast calculation of the exact radiological path for a three-dimensional CT array. , 1985, Medical physics.

[3]  Gengsheng Lawrence Zeng,et al.  Medical Image Reconstruction: A Conceptual Tutorial , 2010 .

[4]  Michael A. King,et al.  Design of a Multi-Pinhole Collimator for I-123 DaTscan Imaging on Dual-Headed SPECT Systems in Combination with a Fan-Beam Collimator , 2016, IEEE Transactions on Nuclear Science.

[5]  A V Bronnikov A filtering approach to image reconstruction in 3D SPECT. , 2000, Physics in medicine and biology.

[6]  P. Bruyant Analytic and iterative reconstruction algorithms in SPECT. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  Mark R. Pickering,et al.  Performance Analysis of an L-SPECT System with Modular Partial Ring Detectors and Multi-Pinhole Arrays , 2018, 2018 Digital Image Computing: Techniques and Applications (DICTA).

[8]  Mark R. Pickering,et al.  Parameters optimization of volumetric reconstruction technique for L-SPECT imaging , 2018, Optical Engineering + Applications.

[9]  C. Vanhove,et al.  Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging. , 2015, Medical physics.

[10]  M. Khalil,et al.  Molecular SPECT Imaging: An Overview , 2011, International journal of molecular imaging.

[11]  Timo Väyrynen,et al.  Methods for measuring the modulation transfer function of gamma camera systems , 2004, European Journal of Nuclear Medicine.

[12]  R. Jaszczak,et al.  Pinhole collimation for ultra-high-resolution, small-field-of-view SPECT. , 1994, Physics in medicine and biology.

[13]  Frans van der Have,et al.  The pinhole: gateway to ultra-high-resolution three-dimensional radionuclide imaging , 2007, European Journal of Nuclear Medicine and Molecular Imaging.

[14]  J. Islamian,et al.  Advances in Pinhole and Multi-Pinhole Collimators for Single Photon Emission Computed Tomography Imaging , 2015, World journal of nuclear medicine.

[15]  Koon-Pong Wong,et al.  An investigation of coded aperture imaging for small animal SPECT , 2000 .

[16]  Simon R. Cherry,et al.  Physics in Nuclear Medicine , 1987 .

[17]  Mark R. Pickering,et al.  Quantitative analysis of L-SPECT system for small animal brain imaging , 2016, SPIE Medical Imaging.

[18]  N. Schramm,et al.  High-resolution SPECT using multi-pinhole collimation , 2002, IEEE Nuclear Science Symposium Conference Record.