Evaluation of associations of the polymorphism in the placentaspecific promoter 1.1 of the CYP19 gene in Black-and-White and Jersey cattle with milk production traits (short communication)

relationship between the SNP of the cytochrome P450 gene (CYP19-PvuII) and milk production traits of Black-and-White and Jersey cattle were analysed. A total of 437 cows were included in the study. A PCR-RFLP was used to genotype. The frequencies of genotypes and alleles for the Black-and-White cows were as follows: 0.8985 - AA, 0.0977 - AB, 0.0038 - BB, and 0.9474 - CYP19 A , 0.0526 - CYP19 B. In the Jersey, all cows were genotyped as CYP19 AA (no polymorphism). There weren't any associations between CYP19-PvuII polymorphism and milk production traits of the investigated cows.

[1]  I. Szatkowska,et al.  PIT1-HinfI gene polymorphism and its associations with milk production traits in polish Black-and-White cattle , 2004 .

[2]  C. Kühn,et al.  Comparison of different statistical-genetic approaches of QTL detection by Evaluating results from a real dairy cattle data set , 2003 .

[3]  A. Dybus.  Associations between Leu/Val polymorphism of growth hormone gene and milk production traits in Black-and-White cattle , 2002 .

[4]  M. Schwerin,et al.  Chromatin structure of the bovine Cyp19 promoter 1.1. DNaseI hypersensitive sites and DNA hypomethylation correlate with placental expression. , 2001, European journal of biochemistry.

[5]  A. Conley,et al.  Mammalian aromatases. , 2001, Reproduction.

[6]  M. Schwerin,et al.  Cis-acting elements regulating the placenta-specific promoter of the bovine Cyp19 gene. , 2000, Journal of molecular endocrinology.

[7]  M. Schwerin,et al.  Isolation of the bovine CYP19 promoter 1.2 and identification of genetic variants. , 2000, Animal genetics.

[8]  M. Georges,et al.  From phenotype to genotype : towards positional cloning of QTL in livestock? , 1999 .

[9]  L. Fésüs,et al.  Placenta-specific transcripts of the aromatase encoding gene include different untranslated first exons in sheep and cattle. , 1999, European journal of biochemistry.

[10]  M. Schwerin,et al.  Three PCR/RFLPs identified in the promoter region 1.1 of the bovine aromatase gene (CYP19). , 1999, Animal Genetics.

[11]  M. Schwerin,et al.  MAPPING OF QUANTITATIVE TRAIT LOCI ON CHROMOSOME 23 IN GERMAN HOLSTEIN CATTLE FAMILIES , 1998 .

[12]  J. Vanselow,et al.  Tissue-Specific Expression of the Bovine Aromatase-Encoding Gene Uses Multiple Transcriptional Start Sites and Alternative First Exons. , 1997, Endocrinology.

[13]  J. Vanselow,et al.  Tissue-specific expression of the bovine aromatase-encoding gene uses multiple transcriptional start sites and alternative first exons. , 1997, Endocrinology.

[14]  Y. J. Topper,et al.  Multiple hormone interactions in the developmental biology of the mammary gland. , 1980, Physiological reviews.