Two Novel Toxins from the Venom of the Scorpion Pandinus imperator Show that the N-terminal Amino Acid Sequence is Important for their Affinities towards Shaker B K+ Channels

[1]  L. Possani,et al.  Structural and functional features of noxiustoxin: a K+ channel blocker. , 1995, Biochemistry and molecular biology international.

[2]  G. Kaczorowski,et al.  Charybdotoxin and its effects on potassium channels. , 1995, The American journal of physiology.

[3]  B. Martin,et al.  Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch. , 1994, The Biochemical journal.

[4]  C. Armstrong,et al.  The relation between ion permeation and recovery from inactivation of ShakerB K+ channels. , 1994, Biophysical journal.

[5]  L. Kolmakova-Partensky,et al.  Intimations of K+ channel structure from a complete functional map of the molecular surface of charybdotoxin. , 1994 .

[6]  B. Martin,et al.  Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels. , 1992, Biochemistry international.

[7]  C. Roumestand,et al.  Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications. , 1992, Biochemistry.

[8]  C. Park,et al.  Mapping function to structure in a channel-blocking peptide: electrostatic mutants of charybdotoxin. , 1992, Biochemistry.

[9]  H. Rochat,et al.  Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom. , 1992, The Journal of biological chemistry.

[10]  Flavio Toma,et al.  Structural basis for functional diversity of animal toxins , 1992 .

[11]  D. Papazian,et al.  Functional expression of Shaker K+ channels in a baculovirus-infected insect cell line , 1990, Neuron.

[12]  G. Giménez-Gallego,et al.  Purification and characterization of a unique, potent inhibitor of apamin binding from Leiurus quinquestriatus hebraeus venom. , 1988, The Journal of biological chemistry.

[13]  B. Martin,et al.  Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+(Ca2+) channel , 1988, FEBS letters.

[14]  B. Martin,et al.  The primary structure of noxiustoxin: A K+ channel blocking peptide, purified from the venom of the scorpion Centruroides noxius Hoffmann , 1982 .

[15]  A. Maelicke,et al.  Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin , 1982, Nature.

[16]  W. Catterall,et al.  Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes. , 1979, The Journal of biological chemistry.