Dermoscopy of childhood flexural comedones: description of 4 cases

There are no financial or personal conflicts of interest relevant to the submitted manuscript. References 1 Zhou LL, Baiberger A. Melasma: systematic review of the systemic treatments. Int J Dermatol 2017; 56: 902–908. 2 Shin JU, Park J, Oh SH, et al. Oral tranexamic acid enhances the efficacy of low-fluence 1064-nm quality-switched neodymium-doped vitrium aluminum garnet laser treatment for melasma in Koreans: a randomized, prospective trial. Dermatol Surg 2013; 39: 435–442. 3 Padhi T, Pradhan S. Oral tranexamic acid with flucinolonebased triple combination cream versus fluocinolone-based triple combination cream alone in melasma: an open labeled randomized comparative trial. Indian J Dermatol 2015; 60: 520. 4 Karn D, Amatya A, Razouria EA, et al. Oral tranexamic acid for the treatment of melasma. Kathmandu Univ Med J. 2012; 10: 40–43. 5 Martin LK, Caperton C, Woolery-Lloyd H, et al. A randomized double-blind placebo controlled study evaluating the effectiveness and tolerability of oral Polypodium leucotomos in patients with melasma [poster reference number 4630]. Presented at American Academy of Dermatology 70th Annual Meeting, San Diego, California: March 16-20, 2012. J Am Acad Dermatol 2012; 66(Suppl 1): AB21. 6 Ahmed AM, Lopez I, Perese F, et al. A randomized, doubleblinded, placebo-controlled trial of oral Polypodium leucotomos extract as an adjunct to sunscreen in the treatment of melasma. JAMA Dermatol 2013; 149: 981–983. 7 Teo WL, Gan E, Jinghan A, et al. Double blind placebo controlled trial to evaluate the effectiveness of a dietary supplement rich in carotenoids as adjunct to topical lightening cream for the treatment of melasma: a pilot study. J Pigment Disorder 2015; 2: 164. 8 Hamadi SA, Mohammed MM, Aljaf AN, et al. The role of topical and oral melatonin in management of melasma patients. J Arab Univ Basic Appl Sci 2009; 8: 30–42. 9 Handog EB, Galang DAVF, Leon-Godinez MA, et al. A randomized, double-blind, placebo-controlled trial of oral procyanidin with vitamins A, C, E for melasma among Filipino women. Int J Dermatol 2009; 48: 896–901. 10 Cohen PR. Melasma treatment: a novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor. Med Hypotheses 2017; 101: 1–5.