CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis

[1]  Angelique W Whitehurst,et al.  Cause and consequence of cancer/testis antigen activation in cancer. , 2014, Annual review of pharmacology and toxicology.

[2]  F. Bertucci,et al.  ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program. , 2013, Cancer research.

[3]  M. Todaro,et al.  Tumor and its microenvironment: a synergistic interplay. , 2013, Seminars in cancer biology.

[4]  H. Jernström,et al.  Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules , 2013, BMC Clinical Pathology.

[5]  Y. Shu,et al.  The impact of chemokine receptor CXCR4 on breast cancer prognosis: a meta-analysis. , 2013, Cancer epidemiology.

[6]  R. Hales,et al.  The Twist Box Domain Is Required for Twist1-induced Prostate Cancer Metastasis , 2013, Molecular Cancer Research.

[7]  Thomas John,et al.  The Role of Cancer-Testis Antigens as Predictive and Prognostic Markers in Non-Small Cell Lung Cancer , 2013, PloS one.

[8]  O. Janssen,et al.  Down-regulation of the cancer/testis antigen 45 (CT45) is associated with altered tumor cell morphology, adhesion and migration , 2013, Cell Communication and Signaling.

[9]  T. Kondo,et al.  Preferential expression of cancer/testis genes in cancer stem-like cells: proposal of a novel sub-category, cancer/testis/stem gene. , 2013, Tissue antigens.

[10]  A. Kozlov,et al.  The Novelty of Human Cancer/Testis Antigen Encoding Genes in Evolution , 2013, International journal of genomics.

[11]  Yuanjie Sun,et al.  Heterogeneous expression of CT10, CT45 and GAGE7 antigens and their prognostic significance in human breast carcinoma. , 2013, Japanese journal of clinical oncology.

[12]  A. Harel-Bellan,et al.  Translational control of TWIST1 expression in MCF-10A cell lines recapitulating breast cancer progression , 2012, Oncogene.

[13]  Arpan Shrivastava,et al.  Cancer Testes Antigens in Breast Cancer: Biological Role, Regulation, and Therapeutic Applicability , 2012, International reviews of immunology.

[14]  S. Gnjatic,et al.  Cancer/testis antigens expression and autologous serological response in a set of Brazilian non-Hodgkin’s lymphoma patients , 2012, Cancer Immunology, Immunotherapy.

[15]  L. O’Driscoll,et al.  MAGE‐D4B is a novel marker of poor prognosis and potential therapeutic target involved in breast cancer tumorigenesis , 2012, International journal of cancer.

[16]  N. Normanno,et al.  The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches , 2012, Expert opinion on therapeutic targets.

[17]  A. Asch,et al.  Post‐transcriptional regulation of the Ras‐ERK/MAPK signaling pathway , 2012, Journal of cellular physiology.

[18]  B. Groner,et al.  c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer , 2012, Oncogene.

[19]  G. Zaman,et al.  Sulf2 gene is alternatively spliced in mammalian developing and tumour tissues with functional implications. , 2011, Biochemical and biophysical research communications.

[20]  A. Jungbluth,et al.  An overview of cancer/testis antigens expression in classical Hodgkin's lymphoma (cHL) identifies MAGE-A family and MAGE-C1 as the most frequently expressed antigens in a set of Brazilian cHL patients , 2011, BMC Cancer.

[21]  Jun Luo,et al.  Cancer/Testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy , 2011, Journal of Translational Medicine.

[22]  G. Kristiansen,et al.  MAGE-C2/CT10 Protein Expression Is an Independent Predictor of Recurrence in Prostate Cancer , 2011, PloS one.

[23]  B. Klein,et al.  SULFs in human neoplasia: implication as progression and prognosis factors , 2011, Journal of Translational Medicine.

[24]  M. Maio,et al.  The biology of cancer testis antigens: Putative function, regulation and therapeutic potential , 2011, Molecular oncology.

[25]  H. Kuwano,et al.  Clinical Significance of Melanoma Antigen-Encoding Gene-1 (MAGE-1) Expression and its Correlation with Poor Prognosis in Differentiated Advanced Gastric Cancer , 2011, Annals of Surgical Oncology.

[26]  A. Simpson,et al.  Multiple Cancer/Testis Antigens Are Preferentially Expressed in Hormone-Receptor Negative and High-Grade Breast Cancers , 2011, PloS one.

[27]  R. Marschalek,et al.  A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia , 2010, BMC Cancer.

[28]  M. Uhlén,et al.  CXCR4 and cancer , 2010, Pathology international.

[29]  Saraswati Sukumar,et al.  The Hox genes and their roles in oncogenesis , 2010, Nature Reviews Cancer.

[30]  Yao-Tseng Chen,et al.  Expression of cancer testis antigen CT45 in classical Hodgkin lymphoma and other B-cell lymphomas , 2010, Proceedings of the National Academy of Sciences.

[31]  J. Gu,et al.  Cancer/Testis Antigens and Clinical Risk Factors for Liver Metastasis of Colorectal Cancer: A Predictive Panel , 2010, Diseases of the colon and rectum.

[32]  G. Botti,et al.  HOX D13 expression across 79 tumor tissue types , 2009, International journal of cancer.

[33]  A. Simpson,et al.  Cancer/testis antigen CT45: Analysis of mRNA and protein expression in human cancer , 2009, International journal of cancer.

[34]  A. Simpson,et al.  Frequency and prognostic relevance of cancer testis antigen 45 expression in multiple myeloma. , 2008, Experimental hematology.

[35]  D. Jin,et al.  CREB − a real culprit in oncogenesis , 2007, The FEBS journal.

[36]  M. Tiemann,et al.  Characterization and Expression of CT45 in Hodgkin's Lymphoma , 2006, Clinical Cancer Research.

[37]  T. Kipps,et al.  CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. , 2006, Blood.

[38]  Z. Werb,et al.  Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. , 2005, Neoplasia.

[39]  Markku Miettinen,et al.  KIT (CD117): A Review on Expression in Normal and Neoplastic Tissues, and Mutations and Their Clinicopathologic Correlation , 2005, Applied immunohistochemistry & molecular morphology : AIMM.

[40]  M. L. Le Beau,et al.  HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. , 2005, Blood.

[41]  Philip M. Murphy,et al.  Chemokines and the molecular basis of cancer metastasis. , 2001, The New England journal of medicine.

[42]  T. Mcclanahan,et al.  Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.

[43]  N. Takahashi.  Aging , 1992, Cell.

[44]  Catia,et al.  A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E , 1992, The Journal of experimental medicine.

[45]  P. Chomez,et al.  A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. , 1991, Science.

[46]  Jihe Zhao,et al.  The Role of chemokine receptor CXCR4 in breast cancer metastasis. , 2013, American journal of cancer research.

[47]  M. Mansukhani,et al.  The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma. , 2004, Cancer immunity.

[48]  Yao-Tseng Chen,et al.  Genomic cloning and localization of CTAG, a gene encoding an autoimmunogenic cancer-testis antigen NY-ESO-1, to human chromosome Xq28. , 1997, Cytogenetics and cell genetics.