cells Nuclear and cytoplasmic AID in extrafollicular and germinal center B

[1]  Lin Yang,et al.  Novel relational database for tissue microarray analysis. , 2009, Archives of pathology & laboratory medicine.

[2]  B. Jungnickel,et al.  Human splenic marginal zone B cells lack expression of activation‐induced cytidine deaminase , 2005, European journal of immunology.

[3]  D. Schatz,et al.  Histone modifications associated with somatic hypermutation. , 2005, Immunity.

[4]  R. Carter,et al.  CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers. , 2005, Immunity.

[5]  Chad W. Euler,et al.  Short-Lived Plasmablasts Dominate the Early Spontaneous Rheumatoid Factor Response: Differentiation Pathways, Hypermutating Cell Types, and Affinity Maturation Outside the Germinal Center1 , 2005, The Journal of Immunology.

[6]  I. Maclennan Germinal centers still hold secrets. , 2005, Immunity.

[7]  Giorgio Cattoretti,et al.  PRDM1/Blimp‐1 is expressed in human B‐lymphocytes committed to the plasma cell lineage , 2005, The Journal of pathology.

[8]  B. Jungnickel,et al.  Differential expression of activation‐induced cytidine deaminase (AID) in nodular lymphocyte‐predominant and classical Hodgkin lymphoma , 2005, The Journal of pathology.

[9]  Vasco M. Barreto,et al.  Activation-induced deaminase: controversies and open questions. , 2005, Trends in immunology.

[10]  Y. Tu,et al.  Cattoretti and Riccardo Dalla-favera Tracking Cd40 Signaling during Germinal Center Development , 2022 .

[11]  Wendy Dean,et al.  Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues , 2004, Journal of Biological Chemistry.

[12]  Ryan T. Phan,et al.  The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells , 2004, Nature.

[13]  L. Staudt,et al.  Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. , 2004, Blood.

[14]  R. Küppers Dissociation of AID expression and activity , 2004 .

[15]  L. Pasqualucci,et al.  Expression of the AID protein in normal and neoplastic B cells. , 2004, Blood.

[16]  James R. Johnson,et al.  Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression , 2004, Science.

[17]  K. Toellner,et al.  Loss of CD154 impairs the Th2 extrafollicular plasma cell response but not early T cell proliferation and interleukin‐4 induction , 2004, Immunology.

[18]  F. Alt,et al.  Replication protein A interacts with AID to promote deamination of somatic hypermutation targets , 2004, Nature.

[19]  M. Watson,et al.  Activation-induced Cytosine Deaminase (AID) Is Actively Exported out of the Nucleus but Retained by the Induction of DNA Breaks* , 2004, Journal of Biological Chemistry.

[20]  T. Honjo,et al.  AID: how does it aid antibody diversity? , 2004, Immunity.

[21]  Vasco M. Barreto,et al.  Somatic Hypermutation Is Limited by CRM1-dependent Nuclear Export of Activation-induced Deaminase , 2004, The Journal of experimental medicine.

[22]  F. Alt,et al.  Induction of Activation-induced Cytidine Deaminase Gene Expression by Il-4 and Cd40 Ligation Is Dependent on Stat6 and Nfkb , 2022 .

[23]  Reiko Shinkura,et al.  Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1 , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Y. Yokota,et al.  Transcription-Coupled Events Associating with Immunoglobulin Switch Region Chromatin , 2003, Science.

[25]  Y. Yokota,et al.  The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression , 2003, The Journal of experimental medicine.

[26]  S. Pileri,et al.  Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology. , 2003, Blood.

[27]  K. Toellner,et al.  Extrafollicular antibody responses , 2003, Immunological reviews.

[28]  Ying-li Yu,et al.  Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells , 2003, Radiation research.

[29]  W. Klapper,et al.  Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas. , 2003, Blood.

[30]  J. Wedekind,et al.  Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. , 2003, Trends in genetics : TIG.

[31]  Andrea Califano,et al.  Transcriptional analysis of the B cell germinal center reaction , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[32]  A. Saxon,et al.  Human Activation-Induced Cytidine Deaminase Is Induced by IL-4 and Negatively Regulated by CD45: Implication of CD45 as a Janus Kinase Phosphatase in Antibody Diversification 1 , 2003, The Journal of Immunology.

[33]  M. Cooke,et al.  Analysis of B Cell Memory Formation Using DNA Microarrays , 2002, Annals of the New York Academy of Sciences.

[34]  P. Casali,et al.  Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells1 , 2002, The Journal of Immunology.

[35]  Chad W. Euler,et al.  Evolution of Autoantibody Responses via Somatic Hypermutation Outside of Germinal Centers , 2002, Science.

[36]  Kuo-I Lin,et al.  Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells , 2002, Molecular and Cellular Biology.

[37]  Ramit Mehr,et al.  Age‐ and tissue‐specific differences in human germinal center B cell selection revealed by analysis of IgVH gene hypermutation and lineage trees , 2002, European journal of immunology.

[38]  C. Milstein,et al.  AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Alberto Martin,et al.  Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas , 2002, Nature.

[40]  K. Toellner,et al.  Low-level Hypermutation in T Cell–independent Germinal Centers Compared with High Mutation Rates Associated with T Cell–dependent Germinal Centers , 2002, The Journal of experimental medicine.

[41]  Thomas Ried,et al.  AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching , 2001, Nature.

[42]  I. Berberich,et al.  Blimp‐1 over‐expression abrogates IL‐4‐ and CD40‐mediated suppression of terminal B cell differentiation but arrests isotype switching , 2001, European journal of immunology.

[43]  F. Deist,et al.  CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[44]  T. Honjo,et al.  Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme , 2000, Cell.

[45]  G. Ghandour,et al.  B‐lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays , 2000, Immunological reviews.

[46]  N. Chiorazzi,et al.  Heterogeneity of Tonsillar Subepithelial B Lymphocytes, the Splenic Marginal Zone Equivalents1 , 2000, The Journal of Immunology.

[47]  H Stein,et al.  A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. , 2000, Blood.

[48]  K. Rajewsky,et al.  Single-cell PCR analysis of T helper cells in human lymph node germinal centers. , 2000, The American journal of pathology.

[49]  C. Murre,et al.  E2A activity is induced during B‐cell activation to promote immunoglobulin class switch recombination , 1999, The EMBO journal.

[50]  T. Honjo,et al.  Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells* , 1999, The Journal of Biological Chemistry.

[51]  Rodney T. Miller,et al.  Blocking of Endogenous Avidin-Binding Activity in Immunohistochemistry: The Use of Skim Milk as an Economical and Effective Substitute for Commercial Biotin Solutions , 1999 .

[52]  Kou-Juey Wu,et al.  Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. , 1999, Science.

[53]  S. Rutz,et al.  Mainly unmutated VH genes rearranged in B cells forming germinal centers in a cutaneous pleomorphic T‐cell lymphoma , 1999 .

[54]  E. Ingulli,et al.  Visualization of specific B and T lymphocyte interactions in the lymph node. , 1998, Science.

[55]  D. LeBrun,et al.  Restricted expression of E2A protein in primary human tissues correlates with proliferation and differentiation. , 1998, The American journal of pathology.

[56]  Yong‐jun Liu Sites of B Lymphocyte Selection, Activation, and Tolerance in Spleen , 1997, The Journal of experimental medicine.

[57]  E. Shacter,et al.  Bcl-2 does not protect Burkitt's lymphoma cells from oxidant-induced cell death. , 1997, Blood.

[58]  J. Banchereau,et al.  Germinal Center Founder Cells Display Propensity for Apoptosis before Onset of Somatic Mutation , 1997, The Journal of experimental medicine.

[59]  É. Mezey,et al.  Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. , 1996, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[60]  J. Danska,et al.  V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. , 1996, Genes & development.

[61]  J. Banchereau,et al.  Normal human IgD+IgM- germinal center B cells can express up to 80 mutations in the variable region of their IgD transcripts. , 1996, Immunity.

[62]  J. Banchereau,et al.  Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. , 1996, Immunity.

[63]  E. Kremmer,et al.  B‐cell proliferation and induction of early G1‐regulating proteins by Epstein‐Barr virus mutants conditional for EBNA2. , 1995, The EMBO journal.

[64]  J. D. Capra,et al.  Analysis of somatic mutation in five B cell subsets of human tonsil , 1994, The Journal of experimental medicine.

[65]  K. Rajewsky,et al.  Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. , 1993, The EMBO journal.

[66]  G. Nossal,et al.  Antigen-driven B cell differentiation in vivo , 1993, The Journal of experimental medicine.

[67]  I. Maclennan,et al.  Quantitative analysis of molecules which distinguish functional compartments within germinal centers , 1993, European journal of immunology.

[68]  C. Berek,et al.  Maturation of the immune response in germinal centers , 1991, Cell.

[69]  Klaus Rajewsky,et al.  Intraclonal generation of antibody mutants in germinal centres , 1991, Nature.

[70]  G. Kelsoe,et al.  In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations , 1991, The Journal of experimental medicine.

[71]  J. Moore,et al.  c-myc protein expression in untransformed fibroblasts. , 1991, Oncogene.

[72]  H. Zola,et al.  Expression of the p70 chain of the IL‐2 receptor on human lymphoid cells: Analysis using a monoclonal antibody and high‐sensitivity immunofluorescence , 1990, Immunology and cell biology.

[73]  F. Rilke,et al.  Terminal deoxynucleotidyl transferase‐positive B cell precursors in fetal lymph nodes and extrahemopoietic tissues , 1989, European journal of immunology.

[74]  N. Maizels,et al.  The T-cell independent antigen, NP-ficoll, primes for a high affinity IgM anti-NP response. , 1988, Molecular immunology.

[75]  L. Sternberger,et al.  The unlabeled antibody method: comparison of peroxidase-antiperoxidase with avidin-biotin complex by a new method of quantification. , 1986, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[76]  K. Lennert,et al.  The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. , 1985, Blood.

[77]  L. Staudt,et al.  Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[78]  Rodney T. Miller,et al.  Blocking of Endogenous Avidin-Binding Activity in Immunohistochemistry: The Use of Egg Whites , 1997 .