PITYRIASIS VEESICOLOR: A CLINICAL AND MYCOLOGICAL INVESTIGATION

SUMMARY. Twenty‐five patients with pityriasis versicolor have been studied clinically and mycologically and the hospital records of a further 62 patients have been analysed. The sex ratio for the whole series was 3 males to 2 females, the age of onset was usually in the early twenties. Nearly all cases in the Cambridge area start in the warmer months of the year. Conjugal cases are reported but a genetic factor in susceptibility is also accepted. Attention is drawn to the extent of the lesions on the limbs and flexural involvement in association with excessive sweating is shown to be common. Pityrosporum orbiculare was cultured from the lesions of 25 of 27 patients and its presence was also detected on uninvolved skin. The evidence for the identity of P. orbiculare and Malassezia furfur is reviewed briefly and the analogy is drawn with yeast/mycelium transition in candidiasis. The ecology of P. orbiculare/M. furfur in pityriasis versicolor is discussed in the light of the results presented.

[1]  S. Roberts PITYROSPORUM ORBICULARE: INCIDENCE AND DISTRIBUTION ON CLINICALLY NORMAL SKIN , 1969, The British journal of dermatology.

[2]  F. Keddie Electron microscopy of Malassezia furfur in tinea versicolor. , 1967, Sabouraudia.

[3]  R. Michałowski,et al.  PITYRIASIS VERSICOLOR IN CHILDREN. , 1963, The British journal of dermatology.

[4]  J. Rice Tinea versicolor confined to the hairy scalp. , 1963, Archives of dermatology.

[5]  F. Malkinson,et al.  Tinea versicolor in steroid-treated patients. Incidence in patients with chronic ulcerative colitis and regional enteritis treated with corticotropin and corticosteroids. , 1962, Archives of dermatology.

[6]  T. Sternberg,et al.  Immunofluorescence studies in tinea versicolor. A preliminary report. , 1961, Archives of dermatology.

[7]  R. C. Burke,et al.  Tinea versicolor: susceptibility factors and experimental infection in human beings. , 1961, The Journal of investigative dermatology.

[8]  O. Cañizares,et al.  Cushing's syndrome and dermatomycosis. , 1959, Archives of dermatology.

[9]  R. Vanbreuseghem Pityriasis versicolor et cuir chevelu. , 1957 .

[10]  H. M. Robinson,et al.  Selenium sulfide in treatment of pityriasis versicolor. , 1956, Journal of the American Medical Association.

[11]  di Menna,et al.  Non‐pathogenic yeasts of the human skin and alimentary tract: A comparative survey , 1954 .

[12]  M. Bell,et al.  Pityrosporum ovale types cultured from normal and seborrheic subjects. , 1954, A M A Archives of Dermatology and Syphilology.

[13]  M. Cohen A simple procedure for staining tinea versicolor (M. furfur) with fountain pen ink. , 1954, The Journal of investigative dermatology.

[14]  I. Martin-Scott THE PITYROSPORUM OVALE , 1952, The British journal of dermatology.

[15]  M. Gordon Lipophilic yeastlike organisms associated with tinea versicolor. , 1951, The Journal of investigative dermatology.

[16]  M. Gordon The Lipophilic Mycoflora of the Skin. I. In Vitro Culture of Pityrosporum Orbiculare N. Sp. , 1951 .

[17]  Sams Wm Humidity: its relation to problems in dermatology. , 1951 .

[18]  W. M. Sams HUMIDITY: ITS RELATION TO PROBLEMS IN DERMATOLOGY , 1951, Southern medical journal.

[19]  M. Marples The incidence of certain skin diseases in western Samoa: a preliminary survey. , 1950, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[20]  R. Burke,et al.  Pityriasis versicolor; atypical clinical and mycologic variations. , 1949, Archives of dermatology and syphilology.

[21]  M. Moore LXXXIII.—MALASSEZIA FURFUR, THE CAUSE OF TINEA VERSICOLOR: CULTIVATION OF THE ORGANISM AND EXPERIMENTAL PRODUCTION OF THE DISEASE , 1940 .