Bax mRNA therapy using cationic liposomes for human malignant melanoma

Bax is a pro‐apoptotic molecule that functions as a tumor suppressor and Bax gene therapy has been examined for various cancers. Gene transfer by mRNA lipofection is more efficient than plasmid DNA lipofection and, in the present study, we examined the anti‐tumor effects in human malignant melanoma cells (HMGs) using Bax mRNA lipofection.

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