Non-contact optical sensing of vocal fold vibrations by secondary speckle patterns.

Vocal folds lesions are commonly diagnosed using an endoscopic-stroboscope. However, the stroboscopic picture of the vocal folds vibrations is subjectively and qualitatively evaluated by the clinician and, due to technical limitations, is unable to accurately distinguish between healthy and pathologic regions. In this paper, we propose two optical approaches for objectively sensing the vocal folds vibrations, using either external or internal laser illumination, based on temporal tracking of the reflected spatial distribution of secondary speckle patterns. The external configuration (the neck) is noninvasive and the internal configuration (the larynx) allows simultaneous extraction of data from multiple sites on the vocal folds. In this paper, we present measurements of healthy human subjects. Quantitative and precise measurements of vibration parameters of the vocal folds will enable a better understanding of hidden pathologies and optimize the diagnosis and treatment.

[1]  Z. Zalevsky,et al.  Large-scale clinical validation of noncontact and continuous extraction of blood pressure via multipoint defocused photonic imaging. , 2018, Applied optics.

[2]  K Nakamura,et al.  Laser Doppler vibrometer (LDV)--a new clinical tool for the otologist. , 1996, The American journal of otology.

[3]  P. Dejonckere,et al.  A basic protocol for functional assessment of voice pathology, especially for investigating the efficacy of (phonosurgical) treatments and evaluating new assessment techniques , 2001, European Archives of Oto-Rhino-Laryngology.

[4]  B. Kremer,et al.  Observer Agreement for Measurements in Videolaryngostroboscopy. , 2017, Journal of voice : official journal of the Voice Foundation.

[5]  H. K. Schutte,et al.  Videokymography: high-speed line scanning of vocal fold vibration. , 1996, Journal of voice : official journal of the Voice Foundation.

[6]  H. K. Schutte,et al.  Videokymography in Voice Disorders: What to Look For? , 2007, The Annals of otology, rhinology, and laryngology.

[7]  S. Rubesin,et al.  Contrast pharyngography: the importance of phonation. , 1987, AJR. American journal of roentgenology.

[8]  Andrea Ricci-Maccarini,et al.  Proposal of a form for the collection of videolaryngostroboscopy basic findings , 2018, European Archives of Oto-Rhino-Laryngology.

[9]  Zeev Zalevsky,et al.  Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern. , 2009, Optics express.

[10]  J. Leendertz,et al.  Interferometric displacement measurement on scattering surfaces utilizing speckle effect , 1970 .

[11]  David J. Ewins,et al.  MODAL TESTING USING A SCANNING LASER DOPPLER VIBROMETER , 1999 .

[12]  Qilian Yu,et al.  An Automatic Method to Quantify the Vibration Properties of Human Vocal Folds via Videokymography , 2003, Folia Phoniatrica et Logopaedica.

[13]  S. Hecht,et al.  INTERMITTENT STIMULATION BY LIGHT : IV. A THEORETICAL INTERPRETATION OF THE QUANTITATIVE DATA OF FLICKER , 1933 .

[14]  Zeev Zalevsky,et al.  Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns. , 2016, Biomedical optics express.

[15]  Zeev Zalevsky,et al.  Demonstration of a Remote Optical Measurement Configuration That Correlates With Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation , 2015, Proceedings of the IEEE.

[16]  Zeev Zalevsky,et al.  Noncontact optical sensor for bone fracture diagnostics. , 2015, Biomedical optics express.

[17]  P. Dejonckere,et al.  Das Stimmdiagnostik-Protokoll der European Laryngological Society (ELS) - erste Erfahrungen im Rahmen einer Multizenterstudie , 2005 .

[18]  J. Goodman.  Some fundamental properties of speckle , 1976 .

[19]  Reliability of laryngostroboscopic evaluation on lesion size and glottal configuration: A revisit , 2014, The Laryngoscope.

[20]  Zeev Zalevsky,et al.  Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern. , 2010, Journal of biomedical optics.