The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial.
暂无分享,去创建一个
Lisa I. Wang | A. Hansen | A. Kapoor | S. Hotte | J. Knox | G. Bjarnason | C. Kollmannsberger | B. Eigl | E. Winquist | C. Canil | D. Heng | D. Soulières | N. Basappa | S. North | P. Zalewski | R. Macfarlane | P. Czaykowski | D. Ernst | P. Venner | B. Boyd | Lisa Wang
[1] T. Olencki,et al. Prospective phase II multi-center study of individualized axitinib (Axi) titration for metastatic renal cell carcinoma (mRCC) after treatment with PD-1 / PD-L1 inhibitors. , 2018 .
[2] W. Rathmell,et al. Phase II Study of Two Weeks on, One Week off Sunitinib Scheduling in Patients With Metastatic Renal Cell Carcinoma. , 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] Bohuslav Melichar,et al. Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal‐Cell Carcinoma , 2018, The New England journal of medicine.
[4] T. Choueiri,et al. Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update , 2018, European journal of cancer.
[5] T. Choueiri,et al. Axitinib in combination with pembrolizumab in patients with advanced renal cell cancer: a non-randomised, open-label, dose-finding, and dose-expansion phase 1b trial. , 2018, The Lancet. Oncology.
[6] R. Motzer,et al. Pazopanib Exposure Relationship with Clinical Efficacy and Safety in the Adjuvant Treatment of Advanced Renal Cell Carcinoma , 2018, Clinical Cancer Research.
[7] C. Porta,et al. Sorafenib dose escalation in treatment‐naïve patients with metastatic renal cell carcinoma: a non‐randomised, open‐label, Phase 2b study , 2017, BJU international.
[8] P. Nathan,et al. Effects of pazopanib (PAZ) and sunitinib (SUN) dose modification on safety and efficacy in patients with metastatic renal cell carcinoma (mRCC) from COMPARZ. , 2017 .
[9] B. Rini,et al. Clinical Effect of Dose Escalation After Disease Progression in Patients With Metastatic Renal Cell Carcinoma , 2017, Clinical genitourinary cancer.
[10] B. Rini,et al. A Phase II Study of Intermittent Sunitinib in Previously Untreated Patients With Metastatic Renal Cell Carcinoma. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] C. Porta,et al. How clinical practice is changing the rules: the sunitinib 2/1 schedule in metastatic renal cell carcinoma , 2017, Expert review of anticancer therapy.
[12] S. Swann,et al. Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma , 2014, British Journal of Cancer.
[13] C. Porta,et al. Impact of adverse events, treatment modifications, and dose intensity on survival among patients with advanced renal cell carcinoma treated with first-line sunitinib: a medical chart review across ten centers in five European countries , 2014, Cancer medicine.
[14] A. Kiss,et al. Reprint of: Outcomes in patients with metastatic renal cell cancer treated with individualized sunitinib therapy: Correlation with dynamic microbubble ultrasound data and review of the literature. , 2014, Urologic oncology.
[15] T. Bathala,et al. Adult UrologyOncology: Adrenal/Renal/Upper Tract/BladderClinical Outcomes for Patients with Metastatic Renal Cell Carcinoma Treated with Alternative Sunitinib Schedules , 2014 .
[16] T. Choueiri,et al. Anti-VEGF therapy in mRCC: differences between Asian and non-Asian patients , 2014, British Journal of Cancer.
[17] N. Vogelzang,et al. Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial. , 2013, The Lancet. Oncology.
[18] J. Reeves,et al. Pazopanib versus sunitinib in metastatic renal-cell carcinoma. , 2013, The New England journal of medicine.
[19] R. Motzer,et al. Axitinib in Metastatic Renal Cell Carcinoma: Results of a Pharmacokinetic and Pharmacodynamic Analysis , 2013, Journal of clinical pharmacology.
[20] E. Jonasch,et al. Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients , 2012, Clinical Cancer Research.
[21] J. Burke,et al. Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] R. Motzer,et al. A retrospective analysis of data from two trials of sunitinib in patients with advanced renal cell carcinoma (RCC): Pitfalls of efficacy subgroup analyses based on dose-reduction status. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[23] G. Demetri,et al. Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis , 2010, Cancer Chemotherapy and Pharmacology.
[24] Xin Huang,et al. Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] B. Rini. Sunitinib , 2007, Reactions Weekly.
[26] D. McDonald,et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. , 2006, The Journal of clinical investigation.
[27] W. Bro,et al. Development and validation of the Functional Assessment of Cancer Therapy-Kidney Symptom Index (FKSI). , 2006, The journal of supportive oncology.
[28] D. Tulsky,et al. The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. , 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[29] G. Bjarnason,et al. Sunitinib dose-escalation after disease progression in metastatic renal cell carcinoma. , 2018, Urologic oncology.
[30] A. Kiss,et al. Outcomes in patients with metastatic renal cell cancer treated with individualized sunitinib therapy: correlation with dynamic microbubble ultrasound data and review of the literature. , 2014, Urologic oncology.
[31] R. Motzer,et al. A retrospective analysis of data from two trials of sunitinib in patients with advanced renal cell carcinoma (RCC): Pitfalls of efficacy subgroup analyses based on dose-reduction status. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.