Cunlanceloic acids A–D: unprecedented labdane diterpenoid dimers with AChE inhibitory and cytotoxic activities from Cunninghamia lanceolata

Four unprecedented labdane diterpenoid dimers with new carbon skeletons, cunlanceloic acids A–D (1–4), were isolated from the cones of Cunninghamia lanceolata.

[1]  S. Fu,et al.  Naturally occurring [4 + 2] type terpenoid dimers: sources, bioactivities and total syntheses. , 2020, Natural product reports.

[2]  Xiao-nian Li,et al.  Huperserratines A and B, Two Macrocyclic Lycopodium Alkaloids with an Unusual Skeleton from Huperzia serrata. , 2020, The Journal of organic chemistry.

[3]  Junjun Liu,et al.  Alterbrassinoids A-D: Fusicoccane-Derived Diterpenoid Dimers Featuring Different Carbon Skeletons from Alternaria brassicicola. , 2019, Organic letters.

[4]  Lixia Chen,et al.  Unusual ent-Labdane Diterpenoid Dimers and their Selective Activation of TRPV Channels. , 2019, The Journal of organic chemistry.

[5]  Hua Zhang,et al.  Cuceolatins A–D: New Bioactive Diterpenoids from the Leaves of Cunninghamia lanceolata , 2019, Chemistry & biodiversity.

[6]  Hui Yang,et al.  Diterpenoids and sesquiterpenoids from the stem bark of Metasequoia glyptostroboides. , 2019, Phytochemistry.

[7]  Tian Zhu,et al.  Taiwanoids A-D, four dimeric diterpenoids featuring tetracyclic [7. 75, 9. 4. 05, 10. 08, 9] octodecane from Taiwania cryptomerioidesim. , 2018, Organic & biomolecular chemistry.

[8]  Xiao-nian Li,et al.  Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora. , 2018, Phytochemistry.

[9]  Ying Sun,et al.  Asymmetric Synthesis of Hispidanin A and Related Diterpenoids. , 2018, Chemistry.

[10]  Haiyang Liu,et al.  Hedychins A and B, 6,7-Dinorlabdane Diterpenoids with a Peroxide Bridge from Hedychium forrestii. , 2018, Organic letters.

[11]  A. Singh,et al.  Recent Advances in Radical C-H Activation/Radical Cross-Coupling. , 2017, Chemical reviews.

[12]  W. Cao,et al.  Asymmetric Total Synthesis of Hispidanin A. , 2017, Angewandte Chemie.

[13]  Lei Zhu,et al.  Bioinspired Asymmetric Synthesis of Hispidanin A. , 2017, Angewandte Chemie.

[14]  Christopher T. Walsh,et al.  Oxidative Cyclization in Natural Product Biosynthesis. , 2017, Chemical reviews.

[15]  Hung‐wen Liu,et al.  Natural [4 + 2]-Cyclases. , 2017, Chemical reviews.

[16]  Sheng Yao,et al.  Taxodikaloids A and B, Two Dimeric Abietane-Type Diterpenoids from Taxodium ascendens Possessing an Oxazoline Ring Linkage. , 2017, Organic letters.

[17]  Hao Hu,et al.  Naturally Occurring Diterpenoid Dimers: Source, Biosynthesis, Chemistry and Bioactivities , 2016, Planta Medica.

[18]  S. Dalal,et al.  Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia. , 2016, Organic & biomolecular chemistry.

[19]  Silong Wang,et al.  Nine new diterpenes from the leaves of plantation-grown Cunninghamia lanceolata. , 2015, Bioorganic & medicinal chemistry letters.

[20]  M. Gu,et al.  Total synthesis of aphadilactones A-D. , 2014, The Journal of organic chemistry.

[21]  Zhen-Yuan Huang,et al.  Hispidanins A-D: four new asymmetric dimeric diterpenoids from the rhizomes of Isodon hispida. , 2014, Organic letters.

[22]  Ang Li,et al.  Total synthesis of taiwaniadducts B, C, and D. , 2014, Journal of the American Chemical Society.

[23]  M. Cassera,et al.  Aphadilactones A-D, four diterpenoid dimers with DGAT inhibitory and antimalarial activities from a Meliaceae plant. , 2014, The Journal of organic chemistry.

[24]  Y. Kuo,et al.  Diterpenoids from the Wood of Cunninghamia konishii , 2013 .

[25]  Guan-Jhong Huang,et al.  Diterpenoids with Anti-Inflammatory Activity from the Wood of Cunninghamia konishii , 2013, Molecules.

[26]  Sheng Yao,et al.  Bicunningines A and B, two new dimeric diterpenes from Cunninghamia lanceolata. , 2012, Organic letters.

[27]  G. Bernardinelli,et al.  The use of X-ray crystallography to determine absolute configuration. , 2008, Chirality.

[28]  G. H. Reed,et al.  Free radical mechanisms in enzymology. , 2006, Chemical reviews.

[29]  Wei‐Lie Xiao,et al.  Bisrubescensins A-C: three new dimeric ent-kauranoids isolated from isodon rubescens. , 2006, Organic letters.

[30]  Y. Kuo,et al.  Labdane-type diterpenoids from the wood of Cunninghamia konishii. , 2002, Chemical & pharmaceutical bulletin.

[31]  D. Yu,et al.  Two new bislabdane-type diterpenoids and three new diterpenoids from the roots of Cunninghamia lanceolata. , 2001, Planta medica.

[32]  Chen,et al.  A new bislabdane-type diterpenoid from the roots of cunninghamia lanceolata , 1999, Journal of natural products.

[33]  E. Ghisalberti.  Bioactive acylphloroglucinol derivatives from Eucalyptus species. , 1996, Phytochemistry.

[34]  D. A. Casteel.  Peroxy natural products. , 2010, Natural product reports.

[35]  M. Miyashita,et al.  Cunninghamic acids A and B, novel bis(labdane)-type diterpenoids from Cunninghamia lanceolata , 1992 .

[36]  T. Mosmann.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.

[37]  K. Courtney,et al.  A new and rapid colorimetric determination of acetylcholinesterase activity. , 1961, Biochemical pharmacology.