The multidrug resistance protein family.
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M. Kool | R. Evers | J. Wijnholds | P. Borst | P Borst | R Evers | M Kool | J Wijnholds | Marcel Kool
[1] J. Wijnholds,et al. Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage , 1998, The Journal of experimental medicine.
[2] Hiroshi Suzuki,et al. Characterization of the Transport Properties of Cloned Rat Multidrug Resistance-associated Protein 3 (MRP3)* , 1999, The Journal of Biological Chemistry.
[3] G. Szakács,et al. Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain* , 1998, The Journal of Biological Chemistry.
[4] Y. Sugiyama,et al. cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3) 1 , 1998 .
[5] K. Kohno,et al. A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. , 1996, Cancer research.
[6] A. Duncan,et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. , 1992, Science.
[7] M. Kool,et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. , 1997, Cancer research.
[8] D. Keppler,et al. Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane , 1999, Hepatology.
[9] D. Keppler,et al. Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. , 1997, Journal of the American Society of Nephrology : JASN.
[10] M. Kool,et al. A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome , 1997, Hepatology.
[11] P. Novikoff,et al. MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[12] Y. Sugiyama,et al. Functional Analysis of a Canalicular Multispecific Organic Anion Transporter Cloned from Rat Liver* , 1998, The Journal of Biological Chemistry.
[13] G. Peters,et al. Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. , 1999, Cancer research.
[14] M. Ouellette,et al. Microbial multidrug-resistance ABC transporters. , 1994, Trends in microbiology.
[15] G. Tusnády,et al. Membrane topology distinguishes a subfamily of the ATP‐binding cassette (ABC) transporters , 1997, FEBS letters.
[16] Y. Sugiyama,et al. Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats. , 1998, Molecular pharmacology.
[17] N. Dean,et al. Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides. , 1996, Biochemical pharmacology.
[18] M. Kool,et al. Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. , 1998, The Journal of clinical investigation.
[19] A. Hutchinson,et al. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. , 1996, Human molecular genetics.
[20] J. Testa,et al. Characterization of MOAT-C and MOAT-D, New Members of the MRP/cMOAT Subfamily of Transporter Proteins , 1999 .
[21] M. Flens,et al. Tissue distribution of the multidrug resistance protein. , 1996, The American journal of pathology.
[22] A. Sartorelli,et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[23] N. Ballatori,et al. Roles of MRP2 and oatp1 in Hepatocellular Export of Reduced Glutathione , 1998, Seminars in liver disease.
[24] R. Davey,et al. The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line. , 1996, British Journal of Cancer.
[25] Y. Sugiyama,et al. Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats. , 1997, Cancer research.
[26] N. Doggett,et al. ARA, a novel ABC transporter, is located at 16p13.1, is deleted in inv(16) leukemias, and is shown to be expressed in primitive hematopoietic precursors. , 1998, Genomics.
[27] W. Lamers,et al. Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport , 1985, Hepatology.
[28] D. Keppler,et al. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. , 1996, Cancer research.
[29] M. Kool,et al. Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. , 1999, Cancer research.
[30] D. Keppler,et al. cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats* , 1996, The Journal of Biological Chemistry.
[31] G. Tusnády,et al. Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein (*) , 1996, The Journal of Biological Chemistry.
[32] R. Flavell,et al. Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins. , 1997, Cancer research.
[33] N. Saijo,et al. cDNA cloning of a short type of multidrug resistance protein homologue, SMRP, from a human lung cancer cell line. , 1997, Biochemical and biophysical research communications.
[34] P. Bosma,et al. Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene , 1996, Science.
[35] T. Uchiumi,et al. A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells. , 1997, Cancer research.
[36] R. Evers,et al. The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[37] S. Cole,et al. Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. , 1998, Cancer research.
[38] K. Ueda,et al. Anti‐cancer drugs and glutathione stimulate vanadate‐induced trapping of nucleotide in multidrug resistance‐associated protein (MRP) , 1997, FEBS letters.
[39] Jos H. Beijnen,et al. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein , 1997, Nature Medicine.
[40] T. Voskoglou-Nomikos,et al. Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[41] T. Ishikawa,et al. Coordinated Induction of MRP/GS-X Pump and γ-Glutamylcysteine Synthetase by Heavy Metals in Human Leukemia Cells* , 1996, The Journal of Biological Chemistry.
[42] T. Ishikawa,et al. Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance. , 1993, The Journal of biological chemistry.
[43] R. Evers,et al. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione , 1999 .
[44] F. Baas,et al. Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines. , 1993, Cancer research.
[45] P. Borst,et al. Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease , 1993, Cell.
[46] D. Bell,et al. Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter. , 1998, Cancer research.
[47] N. Ballatori,et al. ATP-dependent Transport of Reduced Glutathione on YCF1, the Yeast Orthologue of Mammalian Multidrug Resistance Associated Proteins* , 1998, The Journal of Biological Chemistry.
[48] G. Peters,et al. MRP3, an organic anion transporter able to transport anti-cancer drugs. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[49] A. Broeks,et al. Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans. , 1996, The EMBO journal.
[50] D. Keppler,et al. ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. , 1997, The Biochemical journal.
[51] D. Keppler,et al. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. , 1999, Molecular pharmacology.