The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing
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R. Eils | R. Siebert | R. Russell | J. Richter | M. Schlesner | O. Wiestler | M. Montesinos-Rongen | M. Deckert | F. Purschke | I. Buchhalter | I. Nagel | A. Haake | Otmar D. Wiestler | I. Vater | J. Gutwein | Frauke G. Purschke | R. Sprute | Robert B. Russell | N. Mettenmeyer | I. Nazzal | Jana Gutwein
[1] K. Hoang-Xuan,et al. Mutational analysis of primary central nervous system lymphoma , 2014, Oncotarget.
[2] D. Gilbert,et al. Complex correlations: replication timing and mutational landscapes during cancer and genome evolution. , 2014, Current opinion in genetics & development.
[3] R. Siebert,et al. Systems biology of primary CNS lymphoma: from genetic aberrations to modeling in mice , 2014, Acta Neuropathologica.
[4] M. Montesinos-Rongen,et al. Differential effects of CXCR4‐CXCL12‐ and CXCR7‐CXCL12‐mediated immune reactions on murine P0106–125‐induced experimental autoimmune neuritis , 2013, Neuropathology and applied neurobiology.
[5] W. Klapper,et al. Frequent triple-hit expression of MYC, BCL2, and BCL6 in primary lymphoma of the central nervous system and absence of a favorable MYClowBCL2low subgroup may underlie the inferior prognosis as compared to systemic diffuse large B cell lymphomas , 2013, Acta Neuropathologica.
[6] Emmanuel Barillot,et al. Breakpoint Features of Genomic Rearrangements in Neuroblastoma with Unbalanced Translocations and Chromothripsis , 2013, PloS one.
[7] Steven J. M. Jones,et al. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. , 2013, Blood.
[8] David T. W. Jones,et al. Signatures of mutational processes in human cancer , 2013, Nature.
[9] Roland Eils,et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma , 2013, Nature Genetics.
[10] M. Gelabert-González,et al. Primary central nervous system lymphoma. , 2013, Neurologia.
[11] A. Rosenwald,et al. MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma. , 2013, Blood.
[12] David T. W. Jones,et al. Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas , 2013, Acta Neuropathologica.
[13] R. Siebert,et al. Genes regulating the B cell receptor pathway are recurrently mutated in primary central nervous system lymphoma , 2012, Acta Neuropathologica.
[14] L. Staudt,et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[15] M. Fukushi,et al. Teneurin-4 Is a Novel Regulator of Oligodendrocyte Differentiation and Myelination of Small-Diameter Axons in the CNS , 2012, The Journal of Neuroscience.
[16] K. Hoang-Xuan,et al. Recurrent Mutations of MYD88 and TBL1XR1 in Primary Central Nervous System Lymphomas , 2012, Clinical Cancer Research.
[17] D. Zwijnenburg,et al. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes , 2012, Nature.
[18] Eric S. Lander,et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing , 2012, Proceedings of the National Academy of Sciences.
[19] W. Klapper,et al. Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma , 2011, Leukemia.
[20] R. Siebert,et al. Activating L265P mutations of the MYD88 gene are common in primary central nervous system lymphoma , 2011, Acta Neuropathologica.
[21] Manuel A. R. Ferreira,et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 , 2011, Nature Genetics.
[22] Steven J. M. Jones,et al. Frequent mutation of histone modifying genes in non-Hodgkin lymphoma , 2011, Nature.
[23] Raul Rabadan,et al. Analysis of the Coding Genome of Diffuse Large B-Cell Lymphoma , 2011, Nature Genetics.
[24] B. O'neill,et al. Primary Central Nervous System Lymphomas: A Validation Study of Array-Based Comparative Genomic Hybridization in Formalin-Fixed Paraffin-Embedded Tumor Specimens , 2011, Clinical Cancer Research.
[25] K. Karube,et al. Genomic profiling combined with gene expression profiling in primary central nervous system lymphoma. , 2011, Blood.
[26] Dereje D. Jima,et al. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. , 2010, Blood.
[27] Daniela Kenzelmann-Broz,et al. The expression of teneurin-4 in the avian embryo: potential roles in patterning of the limb and nervous system. , 2010, The International journal of developmental biology.
[28] Aris Floratos,et al. geWorkbench: an open source platform for integrative genomics , 2010, Bioinform..
[29] H. Hakonarson,et al. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.
[30] R. Siebert,et al. Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma , 2010, Acta Neuropathologica.
[31] Jan Delabie,et al. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma , 2010, Nature.
[32] Michael O Dorschner,et al. Sequencing newly replicated DNA reveals widespread plasticity in human replication timing , 2009, Proceedings of the National Academy of Sciences.
[33] A. Mottok,et al. Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities. , 2009, Blood.
[34] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[35] R. Siebert,et al. Chromosomal imbalances and partial uniparental disomies in primary central nervous system lymphoma , 2009, Leukemia.
[36] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[37] A. Chott,et al. Mucosa-Associated Lymphoid Tissue Lymphoma: Novel Translocations Including Rearrangements of ODZ2, JMJD2C, and CNN3 , 2008, Clinical Cancer Research.
[38] B. O'neill,et al. Del(6)(q22) and BCL6 rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] A. Rosenwald,et al. Genomic alterations and gene expression in primary diffuse large B‐cell lymphomas of immune‐privileged sites: the importance of apoptosis and immunomodulatory pathways , 2008, The Journal of pathology.
[40] W. Klapper,et al. Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma , 2008, Journal of neuropathology and experimental neurology.
[41] P. Park,et al. Pathway analysis of primary central nervous system lymphoma. , 2008, Blood.
[42] R. Spang,et al. Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell , 2008, Leukemia.
[43] G. Reifenberger,et al. Transcriptional Profiling of the Nuclear Factor-&kgr;B Pathway Identifies a Subgroup of Primary Lymphoma of the Central Nervous System With Low BCL10 Expression , 2007, Journal of neuropathology and experimental neurology.
[44] A. Rosenwald,et al. Mechanisms and Effects of Loss of Human Leukocyte Antigen Class II Expression in Immune-Privileged Site-Associated B-Cell Lymphoma , 2006, Clinical Cancer Research.
[45] J. Fridlyand,et al. Gene expression and angiotropism in primary CNS lymphoma. , 2006, Blood.
[46] G. Reifenberger,et al. Absence of immunoglobulin class switch in primary lymphomas of the central nervous system. , 2005, The American journal of pathology.
[47] C. Schaller,et al. Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation. , 2004, Blood.
[48] R. Siebert,et al. Molecular Characterization of BCL6 Breakpoints in Primary Diffuse Large B‐cell Lymphomas of the Central Nervous System Identifies GAPD as Novel Translocation Partner , 2003, Brain pathology.
[49] S. Minoshima,et al. A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1. , 2003, Biochemical and biophysical research communications.
[50] Ed Schuuring,et al. Mutations in the HLA class II genes leading to loss of expression of HLA-DR and HLA-DQ in diffuse large B-cell lymphoma , 2003, Immunogenetics.
[51] R. Siebert,et al. Interphase Cytogenetic Analysis of Lymphoma‐Associated Chromosomal Breakpoints in Primary Diffuse Large B‐Cell Lymphomas of the Central Nervous System , 2002, Journal of neuropathology and experimental neurology.
[52] Gouri Nanjangud,et al. Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas , 2001, Nature.
[53] E. Jordanova,et al. Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites. , 2000, Blood.
[54] J. Bixby,et al. Growth Cone Steering by Receptor Tyrosine Phosphatase δ Defines a Distinct Class of Guidance Cue , 2000, Molecular and Cellular Neuroscience.
[55] Ash A. Alizadeh,et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling , 2000, Nature.
[56] D. Ellison,et al. V(H) gene sequences from primary central nervous system lymphomas indicate derivation from highly mutated germinal center B cells with ongoing mutational activity. , 1999, Blood.
[57] R. Siebert,et al. Primary lymphoma of the central nervous system: just DLBCL or not? , 2009, Blood.
[58] J. Lilien,et al. Regulation of Signaling by Protein-Tyrosine Phosphatases: Potential Roles in the Nervous System , 2004, Neurochemical Research.
[59] J. Bixby,et al. Growth cone steering by receptor tyrosine phosphatase delta defines a distinct class of guidance cue. , 2000, Molecular and cellular neurosciences.
[60] E. Rodríguez. [Malignant lymphomas]. , 1985, Revista de enfermeria.