Management of non‐neoplastic ovarian cysts with sclerotherapy

Objective: To evaluate sclerotherapy with alcohol and erythromycin in the management of simple ovarian cysts. Methods: Twenty‐four simple ovarian cysts were subjected to sclerotherapy with alcohol and erythromycin. All procedures were performed under local anesthesia and in an outpatient setting. Cytological examination was carried out in all cases and two patients were excluded from the study because of suspicious cytological results. The patients were followed up monthly with color Doppler sonography for more than 12 months. Results: Cyst fluid was serous in 17 cases and dark‐chocolate colored in seven cases. The volume of aspirated fluid ranged from 100 to 220 ml. The size of ovarian masses and cyst‐wall thickness ranged from 5.5 to 8.5 cm and 1.5 to 5 mm, respectively. Cytological analysis of 15 cysts revealed acellular sediment, seven cysts were compatible with endometrioma, and two were reported as suspicious. During the 12‐month follow‐up, seven cyst recurrences were detected. Conclusion: Aspiration and sclerotherapy with alcohol and erythromycin are followed by a relatively high recurrence rate when the aspirate is bloody. However, patients with a simple cyst that is painful or liable to torsion could benefit from sclerotherapy. Such patients, who are at low risk for malignancy, are relieved with sclerotherapy while avoiding surgery.

[1]  C. Zara,et al.  Aspiration of ovarian cysts: laparoscopy or echography? , 1987, Acta Europaea fertilitatis.

[2]  T. Soerensen,et al.  OVARIAN CYSTS: MANAGEMENT BY PUNCTURE? , 1987, The Lancet.

[3]  W. Walker,et al.  Ultrasound guided fine needle aspiration of ovarian cysts: diagnosis and treatment in pregnant and non-pregnant women. , 1990, Clinical radiology.

[4]  S. Schwimer,et al.  Percutaneous ovarian cyst aspiration using continuous transvaginal ultrasonographic monitoring. , 1985, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[5]  W. Frable,et al.  Cellular follicular cyst of the ovary: Fluid cytology mimicking malignancy , 1991, Diagnostic cytopathology.

[6]  V. Antony,et al.  Pleurodesis: state of the art. , 1997, The European respiratory journal.

[7]  D. Fortune,et al.  The ‘simple’ ovarian cyst: aspirate or operate? , 1989, British journal of obstetrics and gynaecology.

[8]  S. Abdrabbo,et al.  Aspiration and tetracycline sclerotherapy for management of simple ovarian cysts , 1995, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[9]  Ying-jv Lu,et al.  Aspiration cytology of neoplastic and non-neoplastic ovarian cysts : Is it accurate ? , 1996 .

[10]  M. Grönroos,et al.  Interventional ultrasound in diagnosis and treatment of ovarian cysts. , 1987, Annales chirurgiae et gynaecologiae. Supplementum.

[11]  J. Castillo,et al.  Failure of talc pleurodesis is associated with increased pleural fibrinolysis. , 1995, American journal of respiratory and critical care medicine.

[12]  P. Bret,et al.  Ovarian cysts in postmenopausal women: preliminary results with transvaginal alcohol sclerosis. Work in progress. , 1992, Radiology.

[13]  T. Harrison,et al.  Aspiration cytology of neoplastic and non-neoplastic ovarian cysts: is it accurate? , 1996, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

[14]  M. Päivänsalo,et al.  Percutaneous aspiration and alcohol sclerotherapy for symptomatic hepatic cysts. An alternative to surgical intervention. , 1989, Annals of surgery.

[15]  S. Yagel,et al.  The Management of Persistent Clear Pelvic Cysts Diagnosed by Ultrasonography , 1988, Obstetrics and gynecology.