Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA , IDH 1 , EGFR , and NF 1 Citation Verhaak
暂无分享,去创建一个
Yuan Qi | Jill P. Mesirov | Li Ding | Terence P. Speed | Paul T. Spellman | Joe W. Gray | Matthew D. Wilkerson | Pablo Tamayo | Wendy Winckler | Gad Getz | Charles M. Perou | Katherine A. Hoadley | Elizabeth Purdom | D. Neil Hayes | Michael Lawrence | Barbara A. Weir | Jann N. Sarkaria | Matthew Meyerson | Cameron Brennan | C. David James | Stacey Gabriel | S. Gabriel | J. Mesirov | R. Wilson | P. Spellman | P. Tamayo | G. Getz | M. Meyerson | C. Perou | T. Speed | H. Feiler | J. Gray | L. Ding | W. Winckler | R. Verhaak | M. Lawrence | Michael J. T. O’Kelly | G. Alexe | B. Weir | E. Purdom | L. Jakkula | V. Wang | C. Brennan | D. Hayes | K. Hoadley | Yuan Qi | A. Kahn | Y. Qi | M. Wilkerson | C. Miller | Todd Golub | Supriya Gupta | J. Hodgson | C. James | J. Sarkaria | Richard K. Wilson | Ari Kahn | Roel G. W. Verhaak | Supriya Gupta | Victoria Wang | C. Ryan Miller | Todd Golub | Gabriele Alexe | Michael O’Kelly | Lakshmi Jakkula | Heidi S. Feiler | J. Graeme Hodgson | Mike S. Lawrence | S. Gabriel | R. Wilson | C. James | D. N. Hayes | Joe W. Gray | Richard K. Wilson | Todd R. Golub | J. G. Hodgson | Li Ding | Gabriele Alexe | Matthew Meyerson | Victoria Wang | C. R. Miller | Pablo Tamayo | Barbara A. Weir | C. D. James | Cameron Brennan | Terry Speed
[1] D. Nelson,et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. , 1993, Journal of the National Cancer Institute.
[2] P. Kleihues,et al. Epidemiology and etiology of gliomas , 2005, Acta Neuropathologica.
[3] A. Verma. MGMT Gene Silencing and Benefit From Temozolomide in Glioblastoma , 2006 .
[4] P. Rousseeuw. Silhouettes: a graphical aid to the interpretation and validation of cluster analysis , 1987 .
[5] J. Uhm. Comprehensive genomic characterization defines human glioblastoma genes and core pathways , 2009 .
[6] Gang Qu,et al. AffyProbeMiner: a web resource for computing or retrieving accurately redefined Affymetrix probe sets , 2007, Bioinform..
[7] R. Tibshirani,et al. Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[8] S. Horvath,et al. Gene Expression Profiling of Gliomas Strongly Predicts Survival , 2004, Cancer Research.
[9] E. Domany,et al. Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] Tracy T Batchelor,et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. , 2006, Cancer research.
[11] T. Golub,et al. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. , 2003, Cancer research.
[12] Jayant P. Menon,et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. , 2006, Cancer cell.
[13] C. Ball,et al. Identification of genes periodically expressed in the human cell cycle and their expression in tumors. , 2002, Molecular biology of the cell.
[14] Alan R. Dabney. ClaNC: point-and-click software for classifying microarrays to nearest centroids , 2006, Bioinform..
[15] Hongye Liu,et al. Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma , 2007, Neuron.
[16] R. McLendon,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[17] Brad T. Sherman,et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.
[18] T. Yoshimoto,et al. Amplification of alpha-platelet-derived growth factor receptor gene lacking an exon coding for a portion of the extracellular region in a primary brain tumor of glial origin. , 1992, Oncogene.
[19] Ben S. Wittner,et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 , 2009, Nature.
[20] M. Wigler,et al. Circular binary segmentation for the analysis of array-based DNA copy number data. , 2004, Biostatistics.
[21] Nicholas J. Wang,et al. Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. , 2009, Neuro-oncology.
[22] M. Noble,et al. Getting a GR(i)P on oligodendrocyte development. , 2004, Developmental biology.
[23] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[24] M. Faist,et al. The role of tumor resection in the treatment of glioblastoma multiforme in adults , 1999, Cancer.
[25] S. Levy,et al. Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[26] S. Vandenberg,et al. PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling , 2006, Neuron.
[27] Robert Gentleman,et al. matchprobes: a Bioconductor package for the sequence-matching of microarray probe elements , 2004, Bioinform..
[28] Ugo Orfanelli,et al. Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma , 2004, Cancer Research.
[29] D. Botstein,et al. Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[30] Paul S Mischel,et al. Identification of molecular subtypes of glioblastoma by gene expression profiling , 2003, Oncogene.
[31] Koji Yoshimoto,et al. Distinct transcription profiles of primary and secondary glioblastoma subgroups. , 2006, Cancer research.
[32] C. Brennan,et al. Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations , 2009, PloS one.
[33] D. Burns,et al. Neurofibromas in NF1: Schwann Cell Origin and Role of Tumor Environment , 2002, Science.
[34] Y. Yonekawa,et al. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. , 1996, Brain pathology.
[35] P. Kleihues,et al. Primary and secondary glioblastomas: from concept to clinical diagnosis. , 1999, Neuro-oncology.
[36] T. Speed,et al. Summaries of Affymetrix GeneChip probe level data. , 2003, Nucleic acids research.
[37] A. Nobel,et al. Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data , 2008 .
[38] Mitchel S Berger,et al. Neural stem cells and the origin of gliomas. , 2005, The New England journal of medicine.
[39] E. Lander,et al. Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma , 2007, Proceedings of the National Academy of Sciences.
[40] Pedro Martínez,et al. Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling , 2006, Molecular Cancer.
[41] L. Chin,et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. , 2007, Genes & development.
[42] Y. Xing,et al. A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function , 2008, The Journal of Neuroscience.
[43] W. Curran,et al. Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: a report using RTOG 90-06. , 1998, International journal of radiation oncology, biology, physics.
[44] Paul S Mischel,et al. Gene expression profiling identifies molecular subtypes of gliomas , 2003, Oncogene.
[45] Thomas D. Wu,et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. , 2006, Cancer cell.
[46] Jill P. Mesirov,et al. Consensus Clustering: A Resampling-Based Method for Class Discovery and Visualization of Gene Expression Microarray Data , 2003, Machine Learning.
[47] J. Rey,et al. Early genetic changes involved in low-grade astrocytic tumor development. , 2006, Current molecular medicine.